Accurate dosimetry with GafChromic EBT film of a 6 MV photon beam in water: what level is achievable?

This paper focuses on the accuracy, in absolute dose measurements, with GafChromicTM EBT film achievable in water for a 6 MV photon beam up to a dose of 2.3 Gy. Motivation is to get an absolute dose detection system to measure up dose distributions in a (water) phantom, to check dose calculations. An Epson 1680 color (red green blue) transmission flatbed scanner has been used as film scanning system, where the response in the red color channel has been extracted and used for the analyses. The influence of the flatbed film scanner on the film based dose detection process was investigated. The scan procedure has been optimized; i.e. for instance a lateral correction curve was derived to correct the scan value, up to 10%, as a function of optical density and lateral position. Sensitometric curves of different film batches were evaluated in portrait and landscape scan mode. Between various batches important variations in sensitometric curve were observed. Energy dependence of the film is negligible, while a slight variation in dose response is observed for very large angles between film surface and incident photon beam. Improved accuracy in absolute dose detection can be obtained by repetition of a film measurement to tackle at least the inherent presence of film inhomogeneous construction. We state that the overall uncertainty is random in absolute EBT film dose detection and of the order of 1.3% (1 SD) under the condition that the film is scanned in a limited centered area on the scanner and at least two films have been applied. At last we advise to check a new film batch on its characteristics compared to available information, before using that batch for absolute dose measurements.

[1]  C. De Wagter,et al.  Precautions and strategies in using a commercial flatbed scanner for radiochromic film dosimetry , 2007, Physics in medicine and biology.

[2]  Thomas LoSasso,et al.  Predicting energy response of radiographic film in a 6 MV x-ray beam using Monte Carlo calculated fluence spectra and absorbed dose. , 2004, Medical physics.

[3]  Nesrin Dogan,et al.  Comparative evaluation of Kodak EDR2 and XV2 films for verification of intensity modulated radiation therapy. , 2002, Physics in medicine and biology.

[4]  M. Butson,et al.  Absorption spectra variations of EBT radiochromic film from radiation exposure , 2005, Physics in medicine and biology.

[5]  M. McEwen,et al.  Characterization of the phantom material virtual water in high-energy photon and electron beams. , 2006, Medical physics.

[6]  Elisa Calamia,et al.  Clinical use of EBT model Gafchromic™ film in radiotherapy. , 2006, Medical physics.

[7]  N. Suchowerska,et al.  Directional dependence in film dosimetry: radiographic and radiochromic film. , 2001, Physics in medicine and biology.

[8]  Jan Seuntjens,et al.  Dosimetric properties of improved GafChromic films for seven different digitizers. , 2004, Medical physics.

[9]  Film dosimetry in water in a 23 MV therapeutic photon beam. , 1995 .

[10]  L. V. van Battum,et al.  The curvature of sensitometric curves for Kodak XV-2 film irradiated with photon and electron beams. , 2006, Medical physics.

[11]  J. Seuntjens,et al.  Accurate skin dose measurements using radiochromic film in clinical applications. , 2006, Medical physics.

[12]  Patrick A Kupelian,et al.  Characterization and use of EBT radiochromic film for IMRT dose verification. , 2006, Medical physics.

[13]  Effects of read-out light sources and ambient light on radiochromic film. , 1998, Physics in medicine and biology.

[14]  J. Rownd,et al.  Characteristics of sensitometric curves of radiographic films. , 2003, Medical physics.

[15]  J Cygler,et al.  GafChromic MD-55: investigated as a precision dosimeter. , 1997, Medical physics.

[16]  Martin J Butson,et al.  Weak energy dependence of EBT gafchromic film dose response in the 50 kVp-10 MVp X-ray range. , 2006, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[17]  D. Huyskens,et al.  A quantitative evaluation of IMRT dose distributions: refinement and clinical assessment of the gamma evaluation. , 2002, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[18]  Antonio González-López Useful optical density range in film dosimetry: limitations due to noise and saturation. , 2007, Physics in medicine and biology.

[19]  G. Cuttone,et al.  Optical characterization of a radiochromic film by total reflectance and transmittance measurements. , 2004, Medical physics.

[20]  M. Butson,et al.  Radiochromic film dosimetry in water phantoms , 2001, Physics in medicine and biology.

[21]  P. Winkler,et al.  Performance analysis of a film dosimetric quality assurance procedure for IMRT with regard to the employment of quantitative evaluation methods , 2005, Physics in medicine and biology.

[22]  Stefan Both,et al.  A study to establish reasonable action limits for patient‐specific quality assurance in intensity‐modulated radiation therapy , 2007, Journal of applied clinical medical physics.

[23]  S. Chiu‐Tsao,et al.  Dose response characteristics of new models of GAFCHROMIC films: dependence on densitometer light source and radiation energy. , 2004, Medical physics.

[24]  Dietmar Georg,et al.  Dosimetric characterization of GafChromic EBT film and its implication on film dosimetry quality assurance , 2007, Physics in medicine and biology.

[26]  Peter E Metcalfe,et al.  Radiochromic film for medical radiation dosimetry , 2003 .

[27]  M. Butson,et al.  Post-irradiation colouration of Gafchromic EBT radiochromic film , 2005, Physics in medicine and biology.

[28]  J. Seuntjens,et al.  Absorption spectroscopy of EBT model GAFCHROMIC film. , 2006, Medical physics.

[29]  J. Dempsey,et al.  TG-69: radiographic film for megavoltage beam dosimetry. , 2007, Medical physics.

[30]  David A Jaffray,et al.  Energy dependence (75 kVp to 18 MV) of radiochromic films assessed using a real-time optical dosimeter. , 2007, Medical physics.

[31]  J. Dempsey,et al.  Important considerations for radiochromic film dosimetry with flatbed CCD scanners and EBT GAFCHROMIC® film. , 2006, Medical physics.

[32]  Benjamin E. Nelms,et al.  A survey on planar IMRT QA analysis , 2007, Journal of applied clinical medical physics.

[33]  A Wambersie,et al.  What degree of accuracy is required and can be achieved in photon and neutron therapy? , 1987, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[34]  B J Mijnheer,et al.  Experimental verification of the air kerma to absorbed dose conversion factor Cw,u. , 1987, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[35]  R. Pötter,et al.  Normalized sensitometric curves for the verification of hybrid IMRT treatment plans with multiple energies. , 2003, Medical physics.

[36]  C. D. Wagter,et al.  Radiochromic EBT film dosimetry: Effect of film orientation and batch on the lateral correction of the scanner , 2007 .

[37]  Investigation of Kodak extended dose range (EDR) film for megavoltage photon beam dosimetry. , 2002, Physics in medicine and biology.

[38]  I. Chetty,et al.  Dosimetric comparison of extended dose range film with ionization measurements in water and lung equivalent heterogeneous media exposed to megavoltage photons , 2003, Journal of applied clinical medical physics.

[39]  B. Mijnheer,et al.  Consistency and simplicity in the determination of absorbed dose to water in high-energy photon beams: a new code of practice. , 1986, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[40]  F. Cremers,et al.  Evaluation of GafChromic EBT prototype B for external beam dose verification. , 2006, Medical physics.

[41]  E. Podgoršak,et al.  Sensitivity of linear CCD array based film scanners used for film dosimetry. , 2006, Medical physics.

[42]  S. Chiu‐Tsao,et al.  Energy dependence of response of new high sensitivity radiochromic films for megavoltage and kilovoltage radiation energies. , 2005, Medical physics.

[43]  C Ross Schmidtlein,et al.  Precise radiochromic film dosimetry using a flat-bed document scanner. , 2005, Medical physics.