Gafchromic EBT film dosimetry in proton beams

The depth dose verification of active scanning proton beams is extremely time consuming with ion chamber measurements for beam data commissioning and patient specific measurements. With widespread use of Gafchromic EBT films, two-dimensional high-resolution dosimetry is explored in a uniform scanning proton beam. The EBT films were exposed parallel to the beam axis in a solid water phantom in order to obtain the depth-dose curve in a single measurement and compared with the gold standard measurement with a parallel plate ion chamber in water. Our results demonstrate that EBT films perform well in determining the proton beam range, with uncertainty of 0.5 mm. It is also found that EBT film response is a function of energy over the effective energy of 50-160 MeV proton beams with the variations less than 10%. However, an under-dosage of up to 20% was observed at the peak of the Bragg curve. An empirically derived correction factor is proposed to account for the EBT energy dependence. With corrections, EBT films can be a useful tool for the depth dose verification of active scanning proton beams, thus saving valuable proton beam time.

[1]  Michael Gillin,et al.  Use of a two-dimensional ionization chamber array for proton therapy beam quality assurance. , 2008, Medical physics.

[2]  B. Coursey,et al.  Investigation of applicability of alanine and radiochromic detectors to dosimetry of proton clinical beams. , 1995, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[3]  P. Andreo,et al.  Absorbed Dose Determination in External Beam Radiotherapy: An International Code of Practice for Dosimetry based on Standards of Absorbed Dose to Water , 2001 .

[4]  C. Allgower,et al.  Clinical characterization of a proton beam continuous uniform scanning system with dose layer stacking. , 2008, Medical physics.

[5]  A. Buenfil,et al.  Experimental study of the response of radiochromic films to proton radiation of low energy , 2009 .

[6]  L. Reinstein,et al.  Comparison of dose response of radiochromic film measured with He-Ne laser, broadband, and filtered light densitometers. , 1997, Medical physics.

[7]  M. G. Sabini,et al.  Radiochromic film dosimetry of a low energy proton beam. , 2000, Medical physics.

[8]  Icru Prescribing, recording, and reporting photon beam therapy , 1993 .

[9]  S. Vatnitsky,et al.  Radiochromic film dosimetry for verification of dose distributions delivered with proton-beam radiosurgery. , 1997, Physics in medicine and biology.

[10]  D. Bonnett,et al.  Supplement to the code of practice for clinical proton dosimetry. ECHED (European Clinical Heavy Particle Dosimetry Group). , 1994, Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology.

[11]  J. Dempsey,et al.  TG-69: radiographic film for megavoltage beam dosimetry. , 2007, Medical physics.

[12]  An application of GafChromic MD-55 film for 67.5 MeV clinical proton beam dosimetry. , 1999, Physics in medicine and biology.

[13]  N. Suchowerska,et al.  Directional dependence in film dosimetry: radiographic and radiochromic film. , 2001, Physics in medicine and biology.

[14]  S. Vatnitsky,et al.  Radiochromic film dosimetry for clinical proton beams. , 1997, Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine.

[15]  H. Tsujii,et al.  ICRU Report No. 78, Prescribing, recording, and reporting proton-beam therapy. , 2007 .