The C. elegans homolog of the p53 tumor suppressor is required for DNA damage-induced apoptosis

[1]  M. Vidal,et al.  High-throughput yeast two-hybrid assays for large-scale protein interaction mapping. , 2001, Methods.

[2]  F. Ausubel,et al.  Programmed cell death mediated by ced-3 and ced-4 protects Caenorhabditis elegans from Salmonella typhimurium-mediated killing , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Zheng Zhou,et al.  CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans , 2001, Cell.

[4]  A. Fire,et al.  Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans. , 2001, Gene.

[5]  P. Boffetta.  Molecular epidemiology , 2001, Journal of internal medicine.

[6]  Sebastian A. Leidel,et al.  Functional genomic analysis of cell division in C. elegans using RNAi of genes on chromosome III , 2000, Nature.

[7]  P. Zipperlen,et al.  Functional genomic analysis of C. elegans chromosome I by systematic RNA interference , 2000, Nature.

[8]  A. Villeneuve,et al.  Transgene-mediated cosuppression in the C. elegans germ line. , 2000, Genes & development.

[9]  K. Hofmann.  Sensitive Protein Comparisons with Profiles and Hidden Markov Models , 2000, Briefings Bioinform..

[10]  C. Harris,et al.  Molecular epidemiology and carcinogenesis: endogenous and exogenous carcinogens. , 2000, Mutation research.

[11]  M. Belvin,et al.  Drosophila p53 Is a Structural and Functional Homolog of the Tumor Suppressor p53 , 2000, Cell.

[12]  G. Rubin,et al.  Drosophila p53 Binds a Damage Response Element at the reaper Locus , 2000, Cell.

[13]  Ronald H. A. Plasterk,et al.  A genetic link between co-suppression and RNA interference in C. elegans , 2000, Nature.

[14]  S. Milstein,et al.  A conserved checkpoint pathway mediates DNA damage--induced apoptosis and cell cycle arrest in C. elegans. , 2000, Molecular cell.

[15]  K. Roemer.  Mutant p53: Gain-of-Function Oncoproteins and Wild-Type p53 Inactivators , 1999, Biological chemistry.

[16]  H. Horvitz,et al.  Genetic control of programmed cell death in the nematode Caenorhabditis elegans. , 1999, Cancer research.

[17]  H. Horvitz,et al.  Genetic control of programmed cell death in the Caenorhabditis elegans hermaphrodite germline. , 1999, Development.

[18]  Y Taya,et al.  A role for ATR in the DNA damage-induced phosphorylation of p53. , 1999, Genes & development.

[19]  T. Dobner,et al.  Quantitation of beta-galactosidase from yeast cells using a chemiluminescent substrate. , 1999, BioTechniques.

[20]  Andrew Smith.  Genome sequence of the nematode C-elegans: A platform for investigating biology , 1998 .

[21]  Y. Yin,et al.  p53-mediated germ cell quality control in spermatogenesis. , 1998, Developmental biology.

[22]  S F Altschul,et al.  Iterated profile searches with PSI-BLAST--a tool for discovery in protein databases. , 1998, Trends in biochemical sciences.

[23]  G. Gil-Gómez,et al.  The role of the tumor suppressor p53 in spermatogenesis , 1998, Cell Death and Differentiation.

[24]  J. Berg.  Genome sequence of the nematode C. elegans: a platform for investigating biology. , 1998, Science.

[25]  Yoichi Taya,et al.  DNA Damage-Induced Phosphorylation of p53 Alleviates Inhibition by MDM2 , 1997, Cell.

[26]  D. Lane,et al.  Tumour suppressors: A developing role for p53? , 1997, Current Biology.

[27]  T. Soussi,et al.  Structural aspects of the p53 protein in relation to gene evolution: a second look. , 1996, Journal of molecular biology.

[28]  Kevin Karplus,et al.  A Flexible Motif Search Technique Based on Generalized Profiles , 1996, Comput. Chem..

[29]  L. Wang,et al.  [Genetic control of programmed cell death]. , 1996, Sheng li ke xue jin zhan [Progress in physiology].

[30]  P. Jeffrey,et al.  Crystal structure of a p53 tumor suppressor-DNA complex: understanding tumorigenic mutations. , 1994, Science.

[31]  S. Friend,et al.  Screening patients for heterozygous p53 mutations using a functional assay in yeast , 1993, Nature genetics.

[32]  M. Hengartner,et al.  Caenorhabditis elegans gene ced-9 protects cells from programmed cell death , 1992, Nature.

[33]  T. Soussi,et al.  Structural aspects of the p53 protein in relation to gene evolution. , 1990, Oncogene.

[34]  N. Saitou,et al.  The neighbor-joining method: a new method for reconstructing phylogenetic trees. , 1987, Molecular biology and evolution.