Molecular basis for selective eosinophil trafficking in asthma: A multistep paradigm.

[1]  L. Koenderman,et al.  Characterization of eosinophil adhesion to TNF-alpha-activated endothelium under flow conditions: alpha 4 integrins mediate initial attachment, and E-selectin mediates rolling. , 1999, Journal of immunology.

[2]  C. Foster,et al.  Soluble P-selectin glycoprotein ligand 1 inhibits ocular inflammation in a murine model of allergy. , 1999, Investigative ophthalmology & visual science.

[3]  J. Gamble,et al.  Stat6 activation is essential for interleukin-4 induction of P-selectin transcription in human umbilical vein endothelial cells. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[4]  K. Patel,et al.  Mechanisms of selective leukocyte recruitment from whole blood on cytokine-activated endothelial cells under flow conditions. , 1999, Journal of immunology.

[5]  J. Schröder,et al.  Th1- and Th2-type cytokines regulate the expression and production of eotaxin and RANTES by human lung fibroblasts. , 1999, American journal of respiratory cell and molecular biology.

[6]  T. Mosmann,et al.  Effects of Th2 cytokines on chemokine expression in the lung: IL-13 potently induces eotaxin expression by airway epithelial cells. , 1999, Journal of immunology.

[7]  E. Minshall,et al.  Eotaxin and monocyte chemotactic protein-4 mRNA expression in small airways of asthmatic and nonasthmatic individuals. , 1999, The Journal of allergy and clinical immunology.

[8]  D. MacGlashan,et al.  Macrophage-derived chemokine induces human eosinophil chemotaxis in a CC chemokine receptor 3- and CC chemokine receptor 4-independent manner. , 1999, The Journal of allergy and clinical immunology.

[9]  S. Bel,et al.  Differential regulation of eosinophil chemokine signaling via CCR3 and non-CCR3 pathways. , 1999, Journal of immunology.

[10]  M. Billah,et al.  Effects of chronic anti-interleukin-5 monoclonal antibody treatment in a murine model of pulmonary inflammation. , 1999, American journal of respiratory cell and molecular biology.

[11]  O. Götze,et al.  The Biologic Role of Interleukin-8: Functional Analysis and Expression of CXCR1 and CXCR2 on Human Eosinophils , 1999 .

[12]  D. Broide,et al.  A comparison of C3a and C5a-mediated stable adhesion of rolling eosinophils in postcapillary venules and transendothelial migration in vitro and in vivo. , 1999, Journal of immunology.

[13]  H. Simon,et al.  Regulation of Eosinophil Apoptosis: Transduction of Survival and Death Signals , 1999, International Archives of Allergy and Immunology.

[14]  A. Kay,et al.  CD34(+)/interleukin-5Ralpha messenger RNA+ cells in the bronchial mucosa in asthma: potential airway eosinophil progenitors. , 1999, American journal of respiratory cell and molecular biology.

[15]  M. Wills-Karp Immunologic basis of antigen-induced airway hyperresponsiveness. , 1999, Annual review of immunology.

[16]  M. Kramper,et al.  Effect of intranasal fluticasone on cellular infiltration, endothelial adhesion molecule expression, and proinflammatory cytokine mRNA in nasal polyp disease. , 1999, The Journal of allergy and clinical immunology.

[17]  B. Furie,et al.  The Biology of P-Selectin Glycoprotein Ligand-1: Its Role as a Selectin Counterreceptor in Leukocyte-Endothelial and Leukocyte-Platelet Interaction , 1999, Thrombosis and Haemostasis.

[18]  W. Powell,et al.  5-oxo-6,8,11,14-eicosatetraenoic acid is a potent stimulator of L-selectin shedding, surface expression of CD11b, actin polymerization, and calcium mobilization in human eosinophils. , 1999, American journal of respiratory cell and molecular biology.

[19]  B. Engelhardt,et al.  Prolonged eosinophil accumulation in allergic lung interstitium of ICAM-2 deficient mice results in extended hyperresponsiveness. , 1999, Immunity.

[20]  D. Staunton,et al.  αdβ2 Integrin Is Expressed on Human Eosinophils and Functions as an Alternative Ligand for Vascular Cell Adhesion Molecule 1 (VCAM-1) , 1998, The Journal of experimental medicine.

[21]  D. Carrasco,et al.  Antigen-induced eosinophilic lung inflammation develops in mice deficient in chemokine eotaxin. , 1998, Blood.

[22]  K. Patel Eosinophil tethering to interleukin-4-activated endothelial cells requires both P-selectin and vascular cell adhesion molecule-1. , 1998, Blood.

[23]  S. Rankin,et al.  Mechanisms of Acute Eosinophil Mobilization from the Bone Marrow Stimulated by Interleukin 5: The Role of Specific Adhesion Molecules and Phosphatidylinositol 3-Kinase , 1998, The Journal of experimental medicine.

[24]  I. Tillie‐Leblond,et al.  Apoptosis, proliferation, and expression of Bcl-2, Fas, and Fas ligand in bronchial biopsies from asthmatics. , 1998, American journal of respiratory cell and molecular biology.

[25]  J. Denburg The origins of basophils and eosinophils in allergic inflammation. , 1998, The Journal of allergy and clinical immunology.

[26]  L. Li,et al.  Th2-induced eotaxin expression and eosinophilia coexist with Th1 responses at the effector stage of lung inflammation. , 1998, Journal of immunology.

[27]  M. Jordana,et al.  Circulating, but not local lung, IL-5 is required for the development of antigen-induced airways eosinophilia. , 1998, The Journal of clinical investigation.

[28]  R. Egan,et al.  Interleukin-5 expression in the bone marrow of sensitized Balb/c mice after allergen challenge. , 1998, American journal of respiratory and critical care medicine.

[29]  M. Teixeira,et al.  Contribution of endothelial selectins and alpha 4 integrins to eosinophil trafficking in allergic and nonallergic inflammatory reactions in skin. , 1998, Journal of immunology.

[30]  W. Busse,et al.  Differential regulation of eosinophil adhesion and transmigration by pulmonary microvascular endothelial cells. , 1998, Journal of immunology.

[31]  C. Martínez-A,et al.  The Coordinated Action of CC Chemokines in the Lung Orchestrates Allergic Inflammation and Airway Hyperresponsiveness , 1998, The Journal of experimental medicine.

[32]  G. Canonica,et al.  Interleukin (IL) 4 and IL-13 act on human lung fibroblasts. Implication in asthma. , 1998, The Journal of clinical investigation.

[33]  S. Akira,et al.  Abrogation of Bronchial Eosinophilic Inflammation and Airway Hyperreactivity in Signal Transducers and Activators of Transcription (STAT)6-deficient Mice , 1998, The Journal of experimental medicine.

[34]  C. Mackay,et al.  The C-C chemokine receptor CCR3 participates in stimulation of eosinophil arrest on inflammatory endothelium in shear flow. , 1998, The Journal of clinical investigation.

[35]  I. Adcock,et al.  Interleukin-4 and lipopolysaccharide synergize to induce vascular cell adhesion molecule-1 expression in human lung microvascular endothelial cells. , 1998, American journal of respiratory cell and molecular biology.

[36]  D. Broide,et al.  Inhibition of eosinophil rolling and recruitment in P-selectin- and intracellular adhesion molecule-1-deficient mice. , 1998, Blood.

[37]  S. Rankin,et al.  Eotaxin induces a rapid release of eosinophils and their progenitors from the bone marrow. , 1998, Blood.

[38]  A. Luster,et al.  Chemokines--chemotactic cytokines that mediate inflammation. , 1998, The New England journal of medicine.

[39]  J. Chin,et al.  Involvement of intercellular adhesion molecule-1 in the antigen-induced infiltration of eosinophils and lymphocytes into the airways in a murine model of pulmonary inflammation. , 1998, American journal of respiratory cell and molecular biology.

[40]  D. Broide,et al.  Inhibition of pulmonary eosinophilia in P-selectin- and ICAM-1-deficient mice. , 1998, American journal of respiratory cell and molecular biology.

[41]  E. Chi,et al.  Blockade of CD49d (alpha4 integrin) on intrapulmonary but not circulating leukocytes inhibits airway inflammation and hyperresponsiveness in a mouse model of asthma. , 1997, The Journal of clinical investigation.

[42]  S. Holgate,et al.  Release of RANTES, MIP-1 alpha, and MCP-1 into asthmatic airways following endobronchial allergen challenge. , 1997, American journal of respiratory and critical care medicine.

[43]  Q. Hamid,et al.  Increased expression of eotaxin in bronchoalveolar lavage and airways of asthmatics contributes to the chemotaxis of eosinophils to the site of inflammation. , 1997, Journal of immunology.

[44]  T. Springer,et al.  P-selectin, L-selectin, and alpha 4 integrin have distinct roles in eosinophil tethering and arrest on vascular endothelial cells under physiological flow conditions. , 1997, Journal of immunology.

[45]  J. Drazen,et al.  Reduction of allergic airway responses in P-selectin-deficient mice. , 1997, Journal of applied physiology.

[46]  M. Peitsch,et al.  Characterisation of macrophage inflammatory protein-5/human CC cytokine-2, a member of the macrophage-inflammatory-protein family of chemokines. , 1997, European journal of biochemistry.

[47]  C. Mackay,et al.  High expression of the chemokine receptor CCR3 in human blood basophils. Role in activation by eotaxin, MCP-4, and other chemokines. , 1997, The Journal of clinical investigation.

[48]  E. Gelfand,et al.  Interleukin-5 Expression in the Lung Epithelium of Transgenic Mice Leads to Pulmonary Changes Pathognomonic of Asthma , 1997, The Journal of experimental medicine.

[49]  R. Djukanović,et al.  Free and complexed interleukin-8 in blood and bronchial mucosa in asthma. , 1997, American journal of respiratory and critical care medicine.

[50]  R. Bravo,et al.  Monocyte chemotactic protein-3 (MCP-3)/fibroblast-induced cytokine (FIC) in eosinophilic inflammation of the airways and the inhibitory effects of an anti-MCP-3/FIC antibody. , 1997, Journal of immunology.

[51]  Kenji Matsumoto,et al.  Regulation of α4 integrin–mediated adhesion of human eosinophils to fibronectin and vascular cell adhesion molecule-1 , 1997 .

[52]  C. Bachert,et al.  Direct demonstration of delayed eosinophil apoptosis as a mechanism causing tissue eosinophilia. , 1997, Journal of immunology.

[53]  R. Gentz,et al.  Molecular and Functional Characterization of  Two Novel Human C-C Chemokines as Inhibitors of  Two Distinct Classes of Myeloid Progenitors , 1997, The Journal of experimental medicine.

[54]  P. Foster,et al.  Relationship between interleukin-5 and eotaxin in regulating blood and tissue eosinophilia in mice. , 1997, The Journal of clinical investigation.

[55]  P. Leder,et al.  Targeted Disruption of the Chemokine Eotaxin Partially Reduces Antigen-induced Tissue Eosinophilia , 1997, The Journal of experimental medicine.

[56]  C. Mackay,et al.  Chemokine receptor usage by human eosinophils. The importance of CCR3 demonstrated using an antagonistic monoclonal antibody. , 1997, The Journal of clinical investigation.

[57]  S. Durham,et al.  Bronchial mucosal expression of the genes encoding chemokines RANTES and MCP-3 in symptomatic atopic and nonatopic asthmatics: relationship to the eosinophil-active cytokines interleukin (IL)-5, granulocyte macrophage-colony-stimulating factor, and IL-3. , 1997, American journal of respiratory cell and molecular biology.

[58]  D. Broide,et al.  E-selectin preferentially supports neutrophil but not eosinophil rolling under conditions of flow in vitro and in vivo. , 1996, Journal of immunology.

[59]  M. Cybulsky,et al.  Eosinophil recruitment to the lung in a murine model of allergic inflammation. The role of T cells, chemokines, and adhesion receptors. , 1996, The Journal of clinical investigation.

[60]  P. Hellewell,et al.  Eotaxin stimulates eosinophil adhesion to human lung microvascular endothelial cells. , 1996, Biochemical and biophysical research communications.

[61]  T. Schall,et al.  Detection of the chemokine RANTES and endothelial adhesion molecules in nasal polyps. , 1996, The Journal of allergy and clinical immunology.

[62]  T. Springer,et al.  Differential regulation of beta 1 and beta 2 integrin avidity by chemoattractants in eosinophils. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[63]  A. Luster,et al.  T cell-dependent regulation of eotaxin in antigen-induced pulmonary eosinophila , 1996, The Journal of experimental medicine.

[64]  F. Symon,et al.  Functional and structural characterization of the eosinophil P-selectin ligand. , 1996, Journal of immunology.

[65]  A. B. Kay,et al.  Pathology of mild, severe, and fatal asthma. , 1996, American journal of respiratory and critical care medicine.

[66]  J. Chin,et al.  Role of very late activation antigen-4 in the antigen-induced accumulation of eosinophils and lymphocytes in the lungs and airway lumen of sensitized brown Norway rats. , 1996, American journal of respiratory cell and molecular biology.

[67]  J. Pan,et al.  Interleukin 4 or oncostatin M induces a prolonged increase in P- selectin mRNA and protein in human endothelial cells , 1996, The Journal of experimental medicine.

[68]  P. Hellewell,et al.  Selectins mediate eosinophil recruitment in vivo: a comparison with their role in neutrophil influx. , 1996, Blood.

[69]  J. M. Cousin,et al.  Opposing effects of glucocorticoids on the rate of apoptosis in neutrophilic and eosinophilic granulocytes. , 1996, Journal of immunology.

[70]  C. Mackay,et al.  Molecular cloning and characterization of a human eotaxin receptor expressed selectively on eosinophils , 1996, The Journal of experimental medicine.

[71]  B. Dewald,et al.  Monocyte chemotactic protein 4 (MCP-4), a novel structural and functional analogue of MCP-3 and eotaxin , 1996, The Journal of experimental medicine.

[72]  L. Picker,et al.  Lymphocyte Homing and Homeostasis , 1996, Science.

[73]  W Newman,et al.  Cloning of the human eosinophil chemoattractant, eotaxin. Expression, receptor binding, and functional properties suggest a mechanism for the selective recruitment of eosinophils. , 1996, The Journal of clinical investigation.

[74]  P. Bradding Human mast cell cytokines , 1996, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[75]  P. Foster,et al.  Interleukin 5 deficiency abolishes eosinophilia, airways hyperreactivity, and lung damage in a mouse asthma model , 1996, The Journal of experimental medicine.

[76]  N. Copeland,et al.  Mouse Eotaxin expression parallels eosinophil accumulation during lung allergic inflammation but it is not restricted to a Th2-type response. , 1996, Immunity.

[77]  M. Arima,et al.  Role of interleukin-4 and vascular cell adhesion molecule-1 in selective eosinophil migration into the airways in allergic asthma. , 1996, American journal of respiratory cell and molecular biology.

[78]  C. Bertrand,et al.  Activation of the Fas receptor on lung eosinophils leads to apoptosis and the resolution of eosinophilic inflammation of the airways. , 1995, The Journal of clinical investigation.

[79]  T. Williams,et al.  Cooperation between interleukin-5 and the chemokine eotaxin to induce eosinophil accumulation in vivo , 1995, The Journal of experimental medicine.

[80]  M. Baggiolini,et al.  Monocyte chemotactic protein MCP-2 activates human basophil and eosinophil leukocytes similar to MCP-3. , 1995, Journal of immunology.

[81]  T. Casale,et al.  Interleukin-8 is a potent mediator of eosinophil chemotaxis through endothelium and epithelium. , 1995, The American journal of physiology.

[82]  A. Wardlaw,et al.  Eosinophils: biology and role in disease. , 1995, Advances in immunology.

[83]  E. Butcher,et al.  L-selectin and very late antigen-4 integrin promote eosinophil rolling at physiological shear rates in vivo. , 1994, Journal of immunology.

[84]  R. Schleimer,et al.  The role of adhesion molecules in human eosinophil and basophil recruitment. , 1994, The Journal of allergy and clinical immunology.

[85]  F. Symon,et al.  Eosinophil adhesion to nasal polyp endothelium is P-selectin-dependent , 1994, The Journal of experimental medicine.

[86]  J. Hsuan,et al.  Eotaxin: a potent eosinophil chemoattractant cytokine detected in a guinea pig model of allergic airways inflammation , 1994, The Journal of experimental medicine.

[87]  A. Minty,et al.  Monocyte chemotactic protein 3 is a most effective basophil- and eosinophil-activating chemokine , 1994, The Journal of experimental medicine.

[88]  A. Wardlaw,et al.  Interleukin‐8 is a chemo‐attractant for eosinophils purified from subjects with a blood eosinophilia but not from normal healthy subjects , 1993, Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology.

[89]  A. Mallet,et al.  Cytokine RANTES released by thrombin-stimulated platelets is a potent attractant for human eosinophils , 1992, The Journal of experimental medicine.

[90]  C. Sanderson Interleukin-5, Eosinophils, and Disease , 1992 .

[91]  A. Wardlaw,et al.  Interleukin-5 selectively enhances the chemotactic response of eosinophils obtained from normal but not eosinophilic subjects. , 1992, Blood.

[92]  G. Taylor,et al.  Identification of guinea pig eosinophil chemotactic factor of anaphylaxis as leukotriene B4 and 8(S),15(S)-dihydroxy-5,9,11,13(Z,E,Z,E)-eicosatetraenoic acid. , 1991, Journal of immunology.

[93]  A J Wardlaw,et al.  Expression of mRNA for interleukin-5 in mucosal bronchial biopsies from asthma. , 1991, The Journal of clinical investigation.

[94]  P. Weller,et al.  The immunobiology of eosinophils. , 1991, The New England journal of medicine.

[95]  N. Thomson,et al.  Asthma : basic mechanisms and clinical management , 1988 .

[96]  A. Wardlaw,et al.  Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils. , 1986, The Journal of clinical investigation.

[97]  E. Goetzl,et al.  Purification and synthesis of eosinophilotactic tetrapeptides of human lung tissue: identification as eosinophil chemotactic factor of anaphylaxis. , 1975, Proceedings of the National Academy of Sciences of the United States of America.

[98]  E D Robin,et al.  Total eosinophil counts in the management of bronchial asthma. , 1975, The New England journal of medicine.

[99]  K. Austen,et al.  AN EOSINOPHIL LEUKOCYTE CHEMOTACTIC FACTOR OF ANAPHYLAXIS , 1971, The Journal of experimental medicine.