Olfactory reference syndrome.

Received November 13, 2006; revised February 13, 2007; accepted February 21, 2007. From the Dept. of Psychiatry and Behavioral Sciences, Temple University Hospital–Episcopal Campus, Philadelphia, PA. Send correspondence and reprint requests to Aurelia N. Bizamcer, M.D., Dept. of Psychiatry and Behavioral Sciences, Temple University Hospital–Episcopal Campus, 100 E. Lehigh Ave., Suite 105, Philadelphia, PA 19125. e-mail: bizamcer@temple.edu 2008 The Academy of Psychosomatic Medicine Olfactory reference syndrome (ORS) is a variant of delusional disorder of somatic type in which one believes that his or her body emits a foul odor that makes people react in a negative way to their body. Which category ORS fits into diagnostically is still being disputed. One of the most important corollaries of the diagnostic debate is the choice of a therapeutic agent; some psychiatrists treat the disorder with antipsychotic medication, others with antidepressants, primarily serotonin reuptake inhibitors (SSRIs), and some clinicians use both. The authors present a case of ORS and then discuss the literature with regard to diagnosis and treatment and then talk about how the they approached the treatment of this patient with ORS.