Age-related decline of contrast sensitivity for second-order stimuli: earlier onset, but slower progression, than for first-order stimuli.

Many visual functions are known to decline during aging (P. D. Spear, 1993). However there has been no clear description as to how contrast sensitivity for second-order stimuli changes across the adult life span. Based on different mechanisms underlying perception of first-/second-order stimuli (Z. L. Lu & G. Sperling, 2001), and J. Faubert's (2002) theory of visual perception and aging, it is expected that perception of these two types of stimuli will change in different ways during aging. In this study we have measured contrast sensitivity for both first- and second-order stimuli in 141 subjects aged from 19 to 79 years old. The results have shown no gender effect but an evident aging effect, i.e., a progressive decline during aging, for perception of both types of stimuli. We have also proposed a piecewise linear model to interpret our data. Based on this model, contrast sensitivity for second-order stimuli begins to decline significantly earlier than for first-order stimuli, but with a slower rate of progression. We suggest the earlier decline for perception of second-order stimuli may be interpreted as reflecting a greater complexity of second-order processing.

[1]  H. J. Tochon-Danguy,et al.  Second Order Components of Moving Plaids Activate Extrastriate Cortex: A Positron Emission Tomography Study , 1999, NeuroImage.

[2]  Shin'ya Nishida,et al.  Dual multiple-scale processing for motion in the human visual System , 1997, Vision Research.

[3]  H. Levitt.  Transformed up-down methods in psychoacoustics. , 1971, The Journal of the Acoustical Society of America.

[4]  M. Frisén,et al.  How good is normal visual acuity? , 2004, Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie.

[5]  M. Landy,et al.  Orientation-selective adaptation to first- and second-order patterns in human visual cortex. , 2006, Journal of neurophysiology.

[6]  Anna M. Clayton,et al.  Aging and the perception of depth and 3-D shape from motion parallax. , 2004, Psychology and aging.

[7]  Z L Lu,et al.  Three-systems theory of human visual motion perception: review and update. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[8]  T. Stuve,et al.  Motion perception and aging. , 1992, Psychology and aging.

[9]  H. Ashida,et al.  FMRI adaptation reveals separate mechanisms for first-order and second-order motion. , 2007, Journal of neurophysiology.

[10]  Functional MRI studies of human vision on a clinical imager , 1992, 1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[11]  A. Peters,et al.  The effects of aging on layer 1 of primary visual cortex in the rhesus monkey. , 2001, Cerebral cortex.

[12]  Jocelyn Faubert,et al.  Visual perception and aging. , 2002, Canadian journal of experimental psychology = Revue canadienne de psychologie experimentale.

[13]  P. D. Spear,et al.  Neural bases of visual deficits during aging , 1993, Vision Research.

[14]  D. H. Kelly.  Adaptation effects on spatio-temporal sine-wave thresholds. , 1972, Vision research.

[15]  R. Snowden,et al.  Motion Perception in the Ageing Visual System: Minimum Motion, Motion Coherence, and Speed Discrimination Thresholds , 2006, Perception.

[16]  Michael Schrauf,et al.  Dynamic vision based on motion-contrast: changes with age in adults , 2000, Experimental Brain Research.

[17]  C. Baker,et al.  Processing of second-order stimuli in the visual cortex. , 2001, Progress in brain research.

[18]  C. Baker.  Central neural mechanisms for detecting second-order motion , 1999, Current Opinion in Neurobiology.

[19]  A. T. Smith,et al.  Detection and Discrimination of First- and Second-Order Motion in Patients with Unilateral Brain Damage , 1997, The Journal of Neuroscience.

[20]  Walter H. Ehrenstein,et al.  Development of dynamic vision based on motion contrast , 1999, Experimental Brain Research.

[21]  Takeo Watanabe,et al.  Neuroimaging of direction-selective mechanisms for second-order motion. , 2003, Journal of neurophysiology.

[22]  G. Newman,et al.  CONFIDENCE INTERVALS , 1987, The Lancet.

[23]  J. Faubert,et al.  Larger effect of aging on the perception of higher-order stimuli , 2000, Vision Research.

[24]  Claes von Hofsten,et al.  Sensitivity to second-order motion in 10-month-olds , 2008, Vision Research.

[25]  C. Baker,et al.  First- and second-order information in natural images: a filter-based approach to image statistics. , 2004, Journal of the Optical Society of America. A, Optics, image science, and vision.

[26]  K. Gegenfurtner,et al.  Differential aging of motion processing mechanisms: Evidence against general perceptual decline , 2008, Vision Research.

[27]  Yuanye Ma,et al.  Degradation of signal timing in cortical areas V1 and V2 of senescent monkeys. , 2005, Cerebral cortex.

[28]  M S Banks,et al.  The development of spatial and temporal contrast sensitivity. , 1982, Current eye research.

[29]  D H Brainard,et al.  The Psychophysics Toolbox. , 1997, Spatial vision.

[30]  Jocelyn Faubert,et al.  Development of static and dynamic perception for luminance-defined and texture-defined information , 2008, Neuroreport.

[31]  B. Brown,et al.  Age-Related Changes in Contrast Sensitivity in Central and Peripheral Retina , 1988, Perception.

[32]  A. Cowey,et al.  The selective impairment of the perception of first-order motion by unilateral cortical brain damage , 1998, Visual Neuroscience.

[33]  Lucia M Vaina,et al.  First-order and second-order motion: neurological evidence for neuroanatomically distinct systems. , 2004, Progress in brain research.

[34]  A. Peters.  The effects of normal aging on myelin and nerve fibers: A review , 2002, Journal of neurocytology.

[35]  R. Haber,et al.  Visual Perception , 2018, Encyclopedia of Database Systems.

[36]  Alan Peters,et al.  The Effects of Normal Aging on Myelinated Nerve Fibers in Monkey Central Nervous System , 2009, Front. Neuroanat..

[37]  A J Schofield,et al.  What Does Second-Order Vision See in an Image? , 2000, Perception.

[38]  Adriane E Seiffert,et al.  Functional MRI studies of human visual motion perception: texture, luminance, attention and after-effects. , 2003, Cerebral cortex.

[39]  Michael S. Landy,et al.  Visual perception of texture , 2002 .

[40]  Zhong-Lin Lu,et al.  Generating high gray-level resolution monochrome displays with conventional computer graphics cards and color monitors , 2003, Journal of Neuroscience Methods.

[41]  J. van Santen,et al.  Temporal covariance model of human motion perception. , 1984, Journal of the Optical Society of America. A, Optics and image science.

[42]  Lihua He,et al.  Functional degradation of visual cortical cells in old cats , 2006, Neurobiology of Aging.

[43]  J. Culham,et al.  Aging Effects on Vernier Hyperacuity: a Function of Oscillation Rate but not Target Contrast , 2001, Optometry and vision science : official publication of the American Academy of Optometry.

[44]  R. Weale,et al.  The aging eye , 1963 .

[45]  J V Odom,et al.  Adult vernier thresholds do not increase with age; vernier bias does. , 1989, Investigative ophthalmology & visual science.

[46]  A. Leventhal,et al.  GABA and Its Agonists Improved Visual Cortical Function in Senescent Monkeys , 2003, Science.

[47]  R. Sekuler,et al.  The effects of aging on motion detection and direction identification , 2007, Vision Research.

[48]  A. Cowey,et al.  Impairment of the perception of second order motion but not first order motion in a patient with unilateral focal brain damage , 1996, Proceedings of the Royal Society of London. Series B: Biological Sciences.

[49]  H. Wilson,et al.  A psychophysically motivated model for two-dimensional motion perception , 1992, Visual Neuroscience.

[50]  A. Leventhal,et al.  Degradation of stimulus selectivity of visual cortical cells in senescent rhesus monkeys , 2000, Nature Neuroscience.

[51]  G. Sáry,et al.  Cerebral regions processing first‐ and higher‐order motion in an opposed‐direction discrimination task , 2003, The European journal of neuroscience.

[52]  U. Tulunay-Keesey,et al.  Threshold and suprathreshold spatiotemporal response throughout adulthood. , 1988, Journal of the Optical Society of America. A, Optics and image science.

[53]  Russell J. Adams,et al.  Using a single test to measure human contrast sensitivity from early childhood to maturity , 2002, Vision Research.

[54]  R. Sekuler,et al.  Contrast sensitivity throughout adulthood , 1982, Vision Research.

[55]  G Sperling,et al.  Two motion perception mechanisms revealed through distance-driven reversal of apparent motion. , 1989, Proceedings of the National Academy of Sciences of the United States of America.

[56]  N E Scott-Samuel,et al.  First-order and second-order signals combine to improve perceptual accuracy. , 2001, Journal of the Optical Society of America. A, Optics, image science, and vision.

[57]  M E Sloane,et al.  Aging and luminance-adaptation effects on spatial contrast sensitivity. , 1988, Journal of the Optical Society of America. A, Optics and image science.

[58]  D G Pelli,et al.  The VideoToolbox software for visual psychophysics: transforming numbers into movies. , 1997, Spatial vision.

[59]  L. Maloney.  Confidence intervals for the parameters of psychometric functions , 1990, Perception & psychophysics.

[60]  Alan C. Evans,et al.  Cortical specialization for processing first- and second-order motion. , 2003, Cerebral cortex.

[61]  A. Leventhal,et al.  Functional degradation of extrastriate visual cortex in senescent rhesus monkeys , 2006, Neuroscience.

[62]  A. Leventhal,et al.  Aging affects contrast response functions and adaptation of middle temporal visual area neurons in rhesus monkeys , 2008, Neuroscience.

[63]  Frederik Michel Dekking,et al.  Confidence intervals for the mean , 2005 .

[64]  P. D. Spear,et al.  Effects of aging on the primate visual system: spatial and temporal processing by lateral geniculate neurons in young adult and old rhesus monkeys. , 1994, Journal of neurophysiology.

[65]  J. Hennig,et al.  The Processing of First- and Second-Order Motion in Human Visual Cortex Assessed by Functional Magnetic Resonance Imaging (fMRI) , 1998, The Journal of Neuroscience.

[66]  David Whitaker,et al.  Neural contribution to spatiotemporal contrast sensitivity decline in healthy ageing eyes , 1990, Vision Research.