Subject-Specific Model of Knee Natural Motion: A Non-invasive Approach

The capability to model human joint motion is a fundamental step towards the definition of effective treatments and medical devices, with an increasing request to adapt the devised models to the specificity of each subject. We present a new approach for the definition of subject-specific models of the knee natural motion. The approach is the result of a combination of two different techniques and exploits the advantages of both. It relays upon non invasive measurements based on which a kinematic model of the natural motion is built, suitable to be extended to the definition of static and dynamic models. Comparison of the model outcomes with in vitro measurements performed on one specimen shows promising results supporting the proposed approach.

[1]  Andrew Lambert,et al.  Accuracy assessment of Tri-plane B-mode ultrasound for non-invasive 3D kinematic analysis of knee joints , 2014, Biomedical engineering online.

[2]  Nicola Sancisi,et al.  On the Role of Passive Structures in the Knee Loaded Motion , 2012, ARK.

[3]  K. Markolf,et al.  Stiffness and laxity of the knee--the contributions of the supporting structures. A quantitative in vitro study. , 1976, The Journal of bone and joint surgery. American volume.

[4]  Nicola Sancisi,et al.  A novel 3D parallel mechanism for the passive motion simulation of the patella-femur-tibia complex , 2011 .

[5]  S. Woo,et al.  Quantitative analysis of human cruciate ligament insertions. , 1999, Arthroscopy : the journal of arthroscopic & related surgery : official publication of the Arthroscopy Association of North America and the International Arthroscopy Association.

[6]  R. Putz,et al.  The effects of exercise on human articular cartilage , 2006, Journal of anatomy.

[7]  E S Grood,et al.  A joint coordinate system for the clinical description of three-dimensional motions: application to the knee. , 1983, Journal of biomechanical engineering.

[8]  K. Johnson Contact Mechanics: Frontmatter , 1985 .

[9]  Nicola Sancisi,et al.  A new test rig for static and dynamic evaluation of knee motion based on a cable-driven parallel manipulator loading system , 2014 .

[10]  Vincenzo Parenti Castelli,et al.  A sound and efficient measure of joint congruence , 2014, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[11]  A Leardini,et al.  Articular surface approximation in equivalent spatial parallel mechanism models of the human knee joint: An experiment-based assessment , 2010, Proceedings of the Institution of Mechanical Engineers. Part H, Journal of engineering in medicine.

[12]  Nicola Sancisi,et al.  A 1-Dof parallel spherical wrist for the modelling of the knee passive motion , 2010 .

[13]  Alexander G Robling,et al.  Biomechanical and molecular regulation of bone remodeling. , 2006, Annual review of biomedical engineering.

[14]  K Hayashi,et al.  Biomechanical studies of the remodeling of knee joint tendons and ligaments. , 1996, Journal of biomechanics.

[15]  F. Noyes,et al.  Limits of movement in the human knee. Effect of sectioning the posterior cruciate ligament and posterolateral structures. , 1988, The Journal of bone and joint surgery. American volume.

[16]  J. Ralphs,et al.  Fibrocartilage in tendons and ligaments — an adaptation to compressive load , 1998, Journal of anatomy.

[17]  Vincenzo Parenti-Castelli,et al.  Joint kinematics from functional adaptation: A validation on the tibio-talar articulation. , 2015, Journal of biomechanics.

[18]  J H Heegaard,et al.  Mechanically modulated cartilage growth may regulate joint surface morphogenesis , 1999, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[19]  L. Blankevoort,et al.  The envelope of passive knee joint motion. , 1988, Journal of biomechanics.

[20]  H. Frost An approach to estimating bone and joint loads and muscle strength in living subjects and skeletal remains , 1999, American journal of human biology : the official journal of the Human Biology Council.

[21]  Vincenzo Parenti-Castelli,et al.  PARALLEL MECHANISMS APPLIED TO THE HUMAN KNEE PASSIVE MOTION SIMULATION , 2000 .

[22]  J. O'Connor,et al.  The components of passive knee movement are coupled to flexion angle. , 2000, Journal of biomechanics.

[23]  A Leardini,et al.  Geometrical changes of knee ligaments and patellar tendon during passive flexion. , 2012, Journal of biomechanics.