The uptake of enflurane during anaesthesia

The uptake of enflurane at a constant end‐expired concentration of 2% in oxygen was studied in 38 patients, ASA 1 or 2, undergoing elective orthopaedic procedures. The anaesthetic was administered using a computer‐controlled closed circle system. Following an initial 4 min period during which the expired concentration of enflurane was established, the rate of uptake of enflurane showed a triexponential decline. The mean cumulative use of enflurane after 60min was 10.7ml, and after 120min was 18.4ml.

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