KAMEL EARAR1*, SEBASTIAN GRADINARU2, GEORGE PARIZA2, FLORIN MICULESCU3, AURORA ANTONIAC3, VASILE DANUT COJOCARU3, AUREL MOHAN4, GINA PINTILIE5, DAN OVIDIU GRIGORESCU6 1 Dunarea de Jos University of Galati, Medicine and Pharmacy Faculty, 47 Domneasca Str., 800008, Galati, Romania. 2 Carol Davila University of Medicine and Pharmacy, 37 Dionisie Lupu Str., 030167, Bucharest, Romania. 3 University Politehnica of Bucharest, 313 Splaiul Independentei Str., 060042, Bucharest, Romania 4 University of Oradea, 1 Universitatii Str., 410087, Oradea, Romania 5 Dunarea de Jos University, Medico Pharmaceutical Research Center of Galati, 47 Domneasca Str., 800008, Galati, Romania 6 Transilvania University, Faculty of Medicine, 29 Eroilor Blvd., 500036, Brasov, Romania