Single-cell lipidomics enabled by dual-polarity ionization and ion mobility-mass spectrometry imaging
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Nathan V. Welham | L. Puglielli | Xudong Shi | Hua Zhang | Yuan Liu | Lauren Fields | Penghsuan Huang | Haiyan Lu | Lingjun Li | Andrew J Schneider | Xindi Tang
[1] K. Dreisewerd,et al. Mass spectrometry imaging to explore molecular heterogeneity in cell culture , 2022, Proceedings of the National Academy of Sciences of the United States of America.
[2] Sen-Lin Tang,et al. High-resolution spatial and genomic characterization of coral-associated microbial aggregates in the coral Stylophora pistillata , 2022, Science advances.
[3] A. Brunner,et al. Unbiased spatial proteomics with single-cell resolution in tissues. , 2022, Molecular cell.
[4] A. Brunner,et al. Deep Visual Proteomics defines single-cell identity and heterogeneity , 2022, Nature Biotechnology.
[5] Andrew P. Bowman,et al. Sphingolipids control dermal fibroblast heterogeneity , 2022, Science.
[6] R. Heeren,et al. ‘On the Spot’ Digital Pathology of Breast Cancer Based on Single-Cell Mass Spectrometry Imaging , 2022, Analytical chemistry.
[7] Felix Schreibing,et al. Mapping the human kidney using single-cell genomics , 2022, Nature Reviews Nephrology.
[8] Z. Bar-Joseph,et al. Temporal modelling using single-cell transcriptomics , 2022, Nature Reviews Genetics.
[9] R. Gross,et al. The foundations and development of lipidomics , 2021, Journal of lipid research.
[10] Elizabeth K. Neumann,et al. Identification of Lipid Heterogeneity and Diversity in the Developing Human Brain , 2021, JACS Au.
[11] K. Raddassi,et al. Single-Cell Multiomics Analysis for Drug Discovery , 2021, Metabolites.
[12] P. Nemes. Mass spectrometry comes of age for subcellular organelles , 2021, Nature Methods.
[13] J. Sweedler,et al. Image-guided MALDI mass spectrometry for high-throughput single-organelle characterization , 2021, Nature Methods.
[14] Z. Ouyang,et al. Enabling High Structural Specificity to Lipidomics by Coupling Photochemical Derivatization with Tandem Mass Spectrometry. , 2021, Accounts of chemical research.
[15] Gustavo S. França,et al. Exploring tissue architecture using spatial transcriptomics , 2021, Nature.
[16] G. Stacey,et al. High-Throughput Analysis of Tissue-Embedded Single Cells by Mass Spectrometry with Bimodal Imaging and Object Recognition. , 2021, Analytical chemistry.
[17] Z. Ju,et al. Metabolomic profiling of single enlarged lysosomes , 2021, Nature Methods.
[18] M. Heikenwalder,et al. SpaceM reveals metabolic states of single cells , 2021, Nature Methods.
[19] K. Dreisewerd,et al. Transmission-Mode MALDI Mass Spectrometry Imaging of Single Cells: Optimizing Sample Preparation Protocols. , 2021, Analytical chemistry.
[20] Fabian J Theis,et al. Ultra‐high sensitivity mass spectrometry quantifies single‐cell proteome changes upon perturbation , 2020, bioRxiv.
[21] R. Sánchez-Martín,et al. Mass Cytometry Tags: Where Chemistry Meets Single-Cell Analysis. , 2020, Analytical chemistry.
[22] R. Drmanac,et al. CoolMPS: evaluation of antibody labeling based massively parallel non-coding RNA sequencing , 2020, Nucleic acids research.
[23] M. Montes-Bayón,et al. Single cell ICP-MS using on line sample introduction systems: Current developments and remaining challenges , 2020 .
[24] Yu Bai,et al. Multi-Dimensional Organic Mass Cytometry: Simultaneous Analysis of Proteins and Metabolites on Single Cells. , 2020, Angewandte Chemie.
[25] Michael Q. Zhang,et al. SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment , 2021, Nature Methods.
[26] L. Pachter,et al. Museum of spatial transcriptomics , 2020, Nature Methods.
[27] J. Soltwisch,et al. Validation of MALDI-MS imaging data of selected membrane lipids in murine brain with and without laser postionization by quantitative nano-HPLC-MS using laser microdissection , 2020, Analytical and Bioanalytical Chemistry.
[28] Xiaomei Yan,et al. Micro-Lensed Fiber Laser Desorption Mass Spectrometry Imaging Reveals Subcellular Distribution of Drugs within Single Cells. , 2020, Angewandte Chemie.
[29] Shana O. Kelley,et al. Single-cell analysis targeting the proteome , 2020, Nature Reviews Chemistry.
[30] Xin Yan,et al. On-Demand Electrochemical Epoxidation in Nano-Electrospray Ionization Mass Spectrometry to Locate Carbon-Carbon Double Bonds. , 2020, Angewandte Chemie.
[31] M. Belov,et al. Transmission-mode MALDI-2 mass spectrometry imaging of cells and tissues at subcellular resolution , 2019, Nature Methods.
[32] P. Dobrzyn,et al. Stearoyl-CoA Desaturase 1 as a Therapeutic Target for the Treatment of Cancer , 2019, Cancers.
[33] Xu Zhao,et al. Label-free mass cytometry for unveiling cellular metabolic heterogeneity. , 2019, Analytical chemistry.
[34] Elizabeth K. Neumann,et al. Lipid Heterogeneity between Astrocytes and Neurons Revealed by Single-Cell MALDI-MS Combined with Immunocytochemical Classification. , 2019, Angewandte Chemie.
[35] J. Xu,et al. Chemical and Topographical Single-Cell Imaging by Near-Field Desorption Mass Spectrometry. , 2019, Angewandte Chemie.
[36] Jody C. May,et al. Ion mobility conformational lipid atlas for high confidence lipidomics , 2019, Nature Communications.
[37] R. Satija,et al. Integrative single-cell analysis , 2019, Nature Reviews Genetics.
[38] E. Lundberg,et al. Spatial proteomics: a powerful discovery tool for cell biology , 2019, Nature Reviews Molecular Cell Biology.
[39] Z. Ouyang,et al. Online photochemical derivatization enables comprehensive mass spectrometric analysis of unsaturated phospholipid isomers , 2019, Nature Communications.
[40] Lai Guan Ng,et al. Dimensionality reduction for visualizing single-cell data using UMAP , 2018, Nature Biotechnology.
[41] Akos Vertes,et al. Single-Cell Mass Spectrometry Approaches to Explore Cellular Heterogeneity. , 2018, Angewandte Chemie.
[42] K. Blennow,et al. Shedding Light on the Molecular Pathology of Amyloid Plaques in Transgenic Alzheimer's Disease Mice Using Multimodal MALDI Imaging Mass Spectrometry. , 2018, ACS chemical neuroscience.
[43] Richard D. Smith,et al. Online Ozonolysis Combined with Ion Mobility-Mass Spectrometry Provides a New Platform for Lipid Isomer Analyses. , 2018, Analytical chemistry.
[44] Seok Chung,et al. Microfluidic co-culture of pancreatic tumor spheroids with stellate cells as a novel 3D model for investigation of stroma-mediated cell motility and drug resistance , 2018, Journal of experimental & clinical cancer research : CR.
[45] Morgan R Alexander,et al. The 3D OrbiSIMS—label-free metabolic imaging with subcellular lateral resolution and high mass-resolving power , 2017, Nature Methods.
[46] Bernhard Spengler,et al. Atmospheric pressure MALDI mass spectrometry imaging of tissues and cells at 1.4-μm lateral resolution , 2016, Nature Methods.
[47] Antoni Ribas,et al. Single-cell analysis tools for drug discovery and development , 2015, Nature Reviews Drug Discovery.
[48] Sean C. Bendall,et al. Multiplexed ion beam imaging of human breast tumors , 2014, Nature Medicine.
[49] Kevin W Eliceiri,et al. A bioengineered heterotypic stroma-cancer microenvironment model to study pancreatic ductal adenocarcinoma. , 2013, Lab on a chip.
[50] A. Vertes,et al. Toward single-cell analysis by plume collimation in laser ablation electrospray ionization mass spectrometry. , 2013, Analytical chemistry.
[51] P. Chaurand,et al. Sublimation of new matrix candidates for high spatial resolution imaging mass spectrometry of lipids: enhanced information in both positive and negative polarities after 1,5-diaminonapthalene deposition. , 2012, Analytical chemistry.
[52] Jeffrey M Spraggins,et al. Enhanced sensitivity for high spatial resolution lipid analysis by negative ion mode matrix assisted laser desorption ionization imaging mass spectrometry. , 2012, Analytical chemistry.
[53] J. Ntambi,et al. Inhibition of stearoyl-CoA desaturase1 activates AMPK and exhibits beneficial lipid metabolic effects in vitro. , 2011, European journal of pharmacology.
[54] J. Falgueyret,et al. Synthesis and biological activity of a potent and orally bioavailable SCD inhibitor (MF-438). , 2010, Bioorganic & medicinal chemistry letters.
[55] O. Ornatsky,et al. Mass cytometry: technique for real time single cell multitarget immunoassay based on inductively coupled plasma time-of-flight mass spectrometry. , 2009, Analytical chemistry.
[56] Michael C. Thomas,et al. Ozonolysis of phospholipid double bonds during electrospray ionization: a new tool for structure determination. , 2006, Journal of the American Chemical Society.