Nanorobots: the ultimate wireless self-propelled sensing and actuating devices.

Natural motor proteins, "bionanorobots," have inspired researchers to develop artificial nanomachines (nanorobots) able to move autonomously by the conversion of chemical to mechanical energy. Such artificial nanorobots are self-propelled by the electrochemical decomposition of the fuel (up to now, hydrogen peroxide). Several approaches have been developed to provide nanorobots with some functionality, such as for controlling their movement, increasing their power output, or transporting different cargo. In this Focus Review we will discuss the recent advances in nanorobots based on metallic nanowires, which can sense, deliver, and actuate in complex environments, looking towards real applications in the not-too-distant future.

[1]  S. Leibler,et al.  An ultrasensitive bacterial motor revealed by monitoring signaling proteins in single cells. , 2000, Science.

[2]  Ashutosh Agarwal,et al.  A smart dust biosensor powered by kinesin motors. , 2009, Nature nanotechnology.

[3]  S. Yao,et al.  Simple and rapid colorimetric sensing of enzymatic cleavage and oxidative damage of single-stranded DNA with unmodified gold nanoparticles as indicator. , 2009, Chemical communications.

[4]  A. Hullmann Who is winning the global nanorace? , 2006, Nature nanotechnology.

[5]  M. Pumera,et al.  Phase-inversion method for incorporation of metal nanoparticles into carbon-nanotube/polymer composites. , 2009, Small.

[6]  George M Whitesides,et al.  Three-dimensional self-assembly of metallic rods with submicron diameters using magnetic interactions. , 2003, Journal of the American Chemical Society.

[7]  Walter F Paxton,et al.  Motility of catalytic nanoparticles through self-generated forces. , 2005, Chemistry.

[8]  J. Hutchinson,et al.  Highly selective directed assembly of functional actomyosin on Au surfaces. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[9]  N. Kovtyukhova Toward Understanding of the Propulsion Mechanism of Rod-Shaped Nanoparticles That Catalyze Gas-Generating Reactions , 2008 .

[10]  H. Craighead,et al.  Powering an inorganic nanodevice with a biomolecular motor. , 2000, Science.

[11]  A. Hudspeth,et al.  Movement of microtubules by single kinesin molecules , 1989, Nature.

[12]  Martin Pumera,et al.  Magnetically trigged direct electrochemical detection of DNA hybridization using Au67 quantum dot as electrical tracer. , 2005, Langmuir : the ACS journal of surfaces and colloids.

[13]  Kalayil Manian Manesh,et al.  Ultrafast catalytic alloy nanomotors. , 2008, Angewandte Chemie.

[14]  Chad A Mirkin,et al.  Polyvalent DNA nanoparticle conjugates stabilize nucleic acids. , 2020, Nano letters.

[15]  Joseph Wang,et al.  Carbon-nanotube-induced acceleration of catalytic nanomotors. , 2008, ACS nano.

[16]  Yanyan Cao,et al.  Catalytic nanomotors: autonomous movement of striped nanorods. , 2004, Journal of the American Chemical Society.

[17]  Viola Vogel,et al.  Selective loading of kinesin-powered molecular shuttles with protein cargo and its application to biosensing. , 2006, Small.

[18]  Cees Dekker,et al.  Motor Proteins at Work for Nanotechnology , 2007, Science.

[19]  Hsinchun Chen,et al.  Trends in nanotechnology patents. , 2008, Nature nanotechnology.

[20]  Geoffrey A Ozin,et al.  Synthetic self-propelled nanorotors. , 2005, Chemical communications.

[21]  Viola Vogel,et al.  Molecular self-assembly of "nanowires"and "nanospools" using active transport. , 2005, Nano letters.

[22]  R. Vale,et al.  The way things move: looking under the hood of molecular motor proteins. , 2000, Science.

[23]  E. Yang,et al.  A multi-walled carbon nanotube-aluminum bimorph nanoactuator. , 2009, Nanotechnology.

[24]  D. Velegol,et al.  Chemotaxis of nonbiological colloidal rods. , 2007, Physical review letters.

[25]  Viola Vogel,et al.  Molecular shuttles: directed motion of microtubules along nanoscale kinesin tracks , 1999 .

[26]  NEMS Based on Carbon Nanotube: New Method of Control , 2008 .

[27]  Walter F Paxton,et al.  Catalytic nanomotors: remote-controlled autonomous movement of striped metallic nanorods. , 2005, Angewandte Chemie.

[28]  Ayusman Sen,et al.  Catalytic motors for transport of colloidal cargo. , 2008, Nano letters.

[29]  G. Whitesides,et al.  Autonomous Movement and Self‐Assembly , 2002 .

[30]  T. Mallouk,et al.  Bipolar electrochemical mechanism for the propulsion of catalytic nanomotors in hydrogen peroxide solutions. , 2006, Langmuir : the ACS journal of surfaces and colloids.

[31]  Jennifer Sturgis,et al.  Bacteria-mediated delivery of nanoparticles and cargo into cells. , 2007, Nature nanotechnology.

[32]  Jonathan D Posner,et al.  Synthetic nanomotors in microchannel networks: directional microchip motion and controlled manipulation of cargo. , 2008, Journal of the American Chemical Society.

[33]  Ben L Feringa,et al.  Autonomous propulsion of carbon nanotubes powered by a multienzyme ensemble. , 2008, Chemical communications.

[34]  Y Wang,et al.  Autonomously moving nanorods at a viscous interface. , 2006, Nano letters.

[35]  Chad A Mirkin,et al.  Rational design and synthesis of catalytically driven nanorotors. , 2007, Journal of the American Chemical Society.

[36]  Adam R. Urbach,et al.  Sub-100 nm confinement of magnetic nanoparticles using localized magnetic field gradients. , 2003, Journal of the American Chemical Society.