Mechanical tissue optical clearing devices: Enhancement of light penetration in ex vivo porcine skin and adipose tissue

The complex morphological structure of tissue and associated variations in the indices of refraction of components therein, provides a highly scattering medium for visible and near‐infrared wavelengths of light. Tissue optical clearing permits delivery of light deeper into tissue, potentially improving the capabilities of various light‐based therapeutic techniques, such as adipose tissue removal or reshaping.

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