Fibronectin Is Present on B‐Cells but not on OKT 3‐Positive T‐Lymphocytes or LEU 11‐Positive Natural Killer Cells

We examined T‐cells, B‐cells, and natural killer cells of four normal individuals for surface‐bound fibronectin (FN) using fluorescence‐activated cell sorter analysis and double fluorescence labeling with monoclonal antibodies. While Leu 12 (CD 19)‐positive B‐cells stained also uniformly with anti‐FN antibody, neither OKT 3 (CD 3)‐positive T‐cells nor Leu 11 (CD 16)‐positive natural killer cells could be labeled with anti‐FN. Although an anti‐FN receptor antibody was not available, these data strongly suggest a distinct pattern of FN‐binding by human lymphocytes.