A naturalistic visual scanning approach to assess selective attention in major depressive disorder

Cognitive biases in information processing play an important role in the etiology and maintenance of emotional disorders. A new methodology to measure attentional biases is presented; this approach encourages subjects to scan and re-scan images with different thematic content, while the pattern of their attentional deployment is continuously monitored by an eye-tracking system. Measures of attentional bias are the total fixation time and the average glance duration on images belonging to a particular theme. Results showed that subjects with depressive disorder (n=8; Beck Depression Inventory Score>/=16) spent significantly more time looking at images with dysphoric themes than subjects in the control group (n=9). Correlation analysis revealed that the differences between the fixation times of the two groups are significantly correlated with the valence ratings, but not with the arousal ratings of the images. The average glance duration on images with social, neutral and threatening themes were similar for both groups, while the average glance duration on images with dysphoric themes was significantly larger for subjects with depressive disorder. The above results suggest that subjects with depressive disorder selectively attend to mood-congruent material and that depression appears to influence the elaborative stages of processing when dysphoric images are viewed.

[1]  K. Mogg,et al.  A cognitive-motivational analysis of anxiety. , 1998, Behaviour research and therapy.

[2]  B. Bergum,et al.  Attention and performance IX , 1982 .

[3]  C. MacLeod,et al.  Cognitive approaches to emotion and emotional disorders. , 1994, Annual review of psychology.

[4]  I. Gotlib,et al.  Selective attention and clinical depression: performance on a deployment-of-attention task. , 1995, Journal of abnormal psychology.

[5]  A. Treisman,et al.  Attention, Space, and Action: Studies in Cognitive Neuroscience , 2001 .

[6]  J. Williams.  Cognitive Psychology and Emotional Disorders , 1991 .

[7]  Corby K. Martin,et al.  Unconscious Memory Bias in Depression: Perceptual and Conceptual Processes , 2000 .

[8]  K. Mogg,et al.  Attentional bias in anxiety and depression: the role of awareness. , 1995, The British journal of clinical psychology.

[9]  M. Posner,et al.  Attention and the detection of signals. , 1980, Journal of experimental psychology.

[10]  Paul A. Wetzel,et al.  An Eye Tracking System for Analysis of Pilots' Scan Paths. , 1997 .

[11]  K. Mogg,et al.  Selective processing of negative information: effects of clinical anxiety, concurrent depression, and awareness. , 1995, Journal of abnormal psychology.

[12]  Biases in eye movements to threatening facial expressions in generalized anxiety disorder and depressive disorder. , 2000 .

[13]  A. Beck,et al.  An inventory for measuring clinical anxiety: psychometric properties. , 1988, Journal of consulting and clinical psychology.

[14]  C. MacLeod,et al.  Attentional bias in emotional disorders. , 1986, Journal of abnormal psychology.

[15]  Philip C. Kendall,et al.  Issues and recommendations regarding use of the Beck Depression Inventory , 1987, Cognitive Therapy and Research.

[16]  T. Dalgleish,et al.  Biases of attention and memory in disorders of anxiety and depression , 1990 .

[17]  Moshe Eizenman,et al.  A new methodology for determining point-of-gaze in head-mounted eye tracking systems , 2004, IEEE Transactions on Biomedical Engineering.

[18]  Ian D. Reid,et al.  A plane measuring device , 1999, Image Vis. Comput..

[19]  N. Moray.  Designing for attention. , 1993 .

[20]  Alan D. Baddeley,et al.  Attention: Selection, Awareness, and Control , 1993 .

[21]  J. Jonides.  Voluntary versus automatic control over the mind's eye's movement , 1981 .

[22]  D. Clark,et al.  Social anxiety and attention away from emotional faces , 1999 .

[23]  Colin M. Macleod.  Half a century of research on the Stroop effect: an integrative review. , 1991, Psychological bulletin.

[24]  R. McNally.  Abnormalities in Anxiety Implications for Cognitive Neuroscience , 1998 .

[25]  D. Williamson,et al.  Evidence for attention to threatening stimuli in depression. , 1996, Behaviour research and therapy.

[26]  Karin Mogg,et al.  Covert and overt orienting of attention to emotional faces in anxiety , 2000 .

[27]  Dirk Hermans,et al.  Eye Movement Registration as a Continuous Index of Attention Deployment: Data from a Group of Spider Anxious Students , 1999 .

[28]  E. Vogel,et al.  Sensory gain control (amplification) as a mechanism of selective attention: electrophysiological and neuroimaging evidence. , 1998, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[29]  C. MacLeod,et al.  Selective attention and emotional vulnerability: assessing the causal basis of their association through the experimental manipulation of attentional bias. , 2002, Journal of abnormal psychology.

[30]  P. Lang,et al.  International Affective Picture System (IAPS): Instruction Manual and Affective Ratings (Tech. Rep. No. A-4) , 1999 .

[31]  A. Beck,et al.  An inventory for measuring depression. , 1961, Archives of general psychiatry.