Stereospecific synthesis of (2S)-2-methyl-3-(2',6'-dimethyl-4'-hydroxyphenyl)-propionic acid (Mdp) and its incorporation into an opioid peptide.
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[1] Amos B. Smith,et al. Novel ligands lacking a positive charge for the δ- and μ-opioid receptors , 2000 .
[2] Peter W. Schiller,et al. The Opioid μ Agonist/δ Antagonist DIPP-NH2[Ψ] Produces a Potent Analgesic Effect, No Physical Dependence, and Less Tolerance than Morphine in Rats , 1999 .
[3] S. Salvadori,et al. Evolution of the Dmt-Tic pharmacophore: N-terminal methylated derivatives with extraordinary delta opioid antagonist activity. , 1997, Journal of medicinal chemistry.
[4] C Evans,et al. The conserved aspartate residue in the third putative transmembrane domain of the delta-opioid receptor is not the anionic counterpart for cationic opiate binding but is a constituent of the receptor binding site. , 1996, Molecular pharmacology.
[5] J. Gage,et al. Total synthesis of (+)-calyculin A , 1992 .
[6] H. Mosberg,et al. Systemic analgesic activity and delta-opioid selectivity in [2,6-dimethyl-Tyr1,D-Pen2,D-Pen5]enkephalin. , 1992, Journal of medicinal chemistry.
[7] R. Periana,et al. A Convenient Asymmetric Synthesis of the Unnatural Amino Acid 2,6-Dimethyl-L-tyrosine , 1992 .
[8] A. McKnight,et al. Selectivities of opioid peptide analogues as agonists and antagonists at the δ‐receptor , 1984 .
[9] Davidr . Evans,et al. Asymmetric alkylation reactions of chiral imide enolates. A practical approach to the enantioselective synthesis of .alpha.-substituted carboxylic acid derivatives , 1982 .
[10] S. Hünig,et al. Farbe und Konstitution IV. Farbstoffe mit gekreuzten Absorptionssystemen II , 1956 .