The search for the retinoblastoma cell of origin
暂无分享,去创建一个
[1] M. Dyer,et al. The first knockout mouse model of retinoblastoma. , 2006, Cell cycle.
[2] I. Livne-bar,et al. The RB Protein Family in Retinal Development and Retinoblastoma: New Insights from New Mouse Models , 2005, Developmental Neuroscience.
[3] S. Donovan,et al. Developmental defects in Rb-deficient retinae , 2004, Vision Research.
[4] Helen Baines,et al. Suppression of the Shh pathway using a small molecule inhibitor eliminates medulloblastoma in Ptc1(+/-)p53(-/-) mice. , 2004, Cancer cell.
[5] W. Gerald,et al. Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control , 2004, Nature.
[6] T. Jacks,et al. Cell type-specific effects of Rb deletion in the murine retina. , 2004, Genes & development.
[7] C. Cepko,et al. Genetic analysis of the homeodomain transcription factor Chx10 in the retina using a novel multifunctional BAC transgenic mouse reporter. , 2004, Developmental biology.
[8] L. Ohno-Machado,et al. Genomic Analysis of Mouse Retinal Development , 2004, PLoS biology.
[9] R. Slack,et al. Cell-specific effects of RB or RB/p107 loss on retinal development implicate an intrinsically death-resistant cell-of-origin in retinoblastoma. , 2004, Cancer cell.
[10] M. Dyer. Mouse models of childhood cancer of the nervous system , 2004, Journal of Clinical Pathology.
[11] Jonathan Gray,et al. Rb regulates proliferation and rod photoreceptor development in the mouse retina , 2004, Nature Genetics.
[12] P. Armitage,et al. The Age Distribution of Cancer and a Multi-stage Theory of Carcinogenesis , 1954, British Journal of Cancer.
[13] A. Berns,et al. Rb and p107 are required for normal cerebellar development and granule cell survival but not for Purkinje cell persistence , 2003, Development.
[14] T. Jacks,et al. Acute mutation of retinoblastoma gene function is sufficient for cell cycle re-entry , 2003, Nature.
[15] M. Dyer. Regulation of proliferation, cell fate specification and differentiation by the homeodomain proteins Prox1, Six3, and Chx10 in the developing retina. , 2003, Cell cycle.
[16] A. McMahon,et al. Retinal ganglion cell-derived sonic hedgehog signaling is required for optic disc and stalk neuroepithelial cell development , 2003, Development.
[17] D. Eisenstat,et al. Dlx1, Dlx2, Pax6, Brn3b, and Chx10 homeobox gene expression defines the retinal ganglion and inner nuclear layers of the developing and adult mouse retina , 2003, The Journal of comparative neurology.
[18] M. Raff,et al. The orientation of cell division influences cell-fate choice in the developing mammalian retina , 2003, Development.
[19] M. Dyer. The Homeodomain Proteins Prox1, Six3 and Chx10 Regulate Proliferation, Cell Fate Specification and Differentiation in the Developing Retina , 2003 .
[20] F. J. Livesey,et al. Prox1 function controls progenitor cell proliferation and horizontal cell genesis in the mammalian retina , 2003, Nature Genetics.
[21] Michael C. Ostrowski,et al. Extra-embryonic function of Rb is essential for embryonic development and viability , 2003, Nature.
[22] A. Trumpp,et al. Conditional Mutation of Rb Causes Cell Cycle Defects without Apoptosis in the Central Nervous System , 2003, Molecular and Cellular Biology.
[23] Z. Onadim,et al. Comparative genomic hybridization of 49 primary retinoblastoma tumors identifies chromosomal regions associated with histopathology, progression, and patient outcome , 2003, Genes, chromosomes & cancer.
[24] Seth Blackshaw,et al. MicroSAGE is highly representative and reproducible but reveals major differences in gene expression among samples obtained from similar tissues , 2003, Genome Biology.
[25] E. Harlow,et al. The retinoblastoma tumour suppressor in development and cancer , 2002, Nature Reviews Cancer.
[26] David S. Park,et al. Telencephalon‐specific Rb knockouts reveal enhanced neurogenesis, survival and abnormal cortical development , 2002, The EMBO journal.
[27] B. Gallie,et al. Genomic amplification in retinoblastoma narrowed to 0.6 megabase on chromosome 6p containing a kinesin-like gene, RBKIN. , 2002, Cancer research.
[28] Wen-Hwa Lee,et al. Retinoblastoma tumor suppressor and genome stability. , 2002, Advances in cancer research.
[29] Seth Blackshaw,et al. Comprehensive Analysis of Photoreceptor Gene Expression and the Identification of Candidate Retinal Disease Genes , 2001, Cell.
[30] J. Harbour,et al. Molecular basis of low-penetrance retinoblastoma. , 2001, Archives of ophthalmology.
[31] T. Jacks,et al. Cell‐autonomous and non‐cell‐autonomous functions of the Rb tumor suppressor in developing central nervous system , 2001, The EMBO journal.
[32] C. Cepko,et al. p27Kip1 and p57Kip2 Regulate Proliferation in Distinct Retinal Progenitor Cell Populations , 2001, The Journal of Neuroscience.
[33] C. Cepko,et al. Regulating proliferation during retinal development , 2001, Nature Reviews Neuroscience.
[34] F. Guillemot,et al. Pax6 Is Required for the Multipotent State of Retinal Progenitor Cells , 2001, Cell.
[35] N. Dyson,et al. p107 and p130: versatile proteins with interesting pockets. , 2001, Experimental cell research.
[36] M. Xiang,et al. The Ath5 proneural genes function upstream of Brn3 POU domain transcription factor genes to promote retinal ganglion cell development. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[37] F. Christians,et al. E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. , 2001, Genes & development.
[38] H. Rehder,et al. Marked differences in unilateral isolated retinoblastomas from young and older children studied by comparative genomic hybridization , 2001, Human Genetics.
[39] F. J. Livesey,et al. Vertebrate neural cell-fate determination: Lessons from the retina , 2001, Nature Reviews Neuroscience.
[40] J. Rutka,et al. Molecular Insight into Medulloblastoma and Central Nervous System Primitive Neuroectodermal Tumor Biology from Hereditary Syndromes: A Review , 2000, Neurosurgery.
[41] A. Aurias,et al. Detection of chromosome imbalances in retinoblastoma by parallel karyotype and CGH analyses , 2000, Genes, chromosomes & cancer.
[42] B. Gallie,et al. Retinoblastoma: the disease, gene and protein provide critical leads to understand cancer. , 2000, Seminars in cancer biology.
[43] C. Cepko,et al. All Brn3 genes can promote retinal ganglion cell differentiation in the chick. , 2000, Development.
[44] A. Berns,et al. Induction of medulloblastomas in p53-null mutant mice by somatic inactivation of Rb in the external granular layer cells of the cerebellum. , 2000, Genes & development.
[45] C. Cepko,et al. Late Retinal Progenitor Cells Show Intrinsic Limitations in the Production of Cell Types and the Kinetics of Opsin Synthesis , 2000, The Journal of Neuroscience.
[46] D. Hanahan,et al. The Hallmarks of Cancer , 2000, Cell.
[47] B. Gallie,et al. Developmental basis of retinal-specific induction of cancer by RB mutation. , 1999, Cancer research.
[48] C. Cepko,et al. Extrinsic and intrinsic factors control the genesis of amacrine and cone cells in the rat retina. , 1999, Development.
[49] Richard L. Maas,et al. Regulation of Pax6 expression is conserved between mice and flies. , 1999, Development.
[50] M. Scott,et al. Control of Neuronal Precursor Proliferation in the Cerebellum by Sonic Hedgehog , 1999, Neuron.
[51] M. Scott,et al. Hedgehog and Patched in Neural Development and Disease , 1998, Neuron.
[52] R. Masland,et al. The Major Cell Populations of the Mouse Retina , 1998, The Journal of Neuroscience.
[53] Dan Goldowitz,et al. The cells and molecules that make a cerebellum , 1998, Trends in Neurosciences.
[54] A. Berns,et al. p107 is a suppressor of retinoblastoma development in pRb-deficient mice. , 1998, Genes & development.
[55] C. Cepko,et al. Crx, a Novel otx-like Homeobox Gene, Shows Photoreceptor-Specific Expression and Regulates Photoreceptor Differentiation , 1997, Cell.
[56] M. Scott,et al. Altered neural cell fates and medulloblastoma in mouse patched mutants. , 1997, Science.
[57] R. Mcinnes,et al. Pax-6, Prox 1, and Chx10 homeobox gene expression correlates with phenotypic fate of retinal precursor cells. , 1997, Investigative ophthalmology & visual science.
[58] C. Cepko,et al. Subsets of retinal progenitors display temporally regulated and distinct biases in the fates of their progeny. , 1997, Development.
[59] C. Cepko,et al. Postmitotic cells fated to become rod photoreceptors can be respecified by CNTF treatment of the retina. , 1997, Development.
[60] V. Wallace,et al. Expression of Sonic hedgehog and its putative role as a precursor cell mitogen in the developing mouse retina. , 1997, Development.
[61] T. Roderick,et al. Ocular retardation mouse caused by Chx10 homeobox null allele: impaired retinal progenitor proliferation and bipolar cell differentiation , 1996, Nature Genetics.
[62] T. Schwartz,et al. Retinoblastoma. Cell of origin. , 1995, Archives of ophthalmology.
[63] A. Balmain,et al. Induction of different genetic changes by different classes of chemical carcinogens during progression of mouse skin tumors , 1994, Molecular carcinogenesis.
[64] A. Berns,et al. Developmental rescue of an embryonic‐lethal mutation in the retinoblastoma gene in chimeric mice. , 1994, The EMBO journal.
[65] D. Kooy,et al. Developmental expression of a novel murine homeobox gene (Chx10): Evidence for roles in determination of the neuroretina and inner nuclear layer , 1994, Neuron.
[66] A. Balmain,et al. How many mutations are required for tumorigenesis? implications from human cancer data , 1993 .
[67] A. Berns,et al. Requirement for a functional Rb-1 gene in murine development , 1992, Nature.
[68] R. Weinberg,et al. Effects of an Rb mutation in the mouse , 1992, Nature.
[69] A. Bradley,et al. Mice deficient for Rb are nonviable and show defects in neurogenesis and haematopoiesis , 1992, Nature.
[70] B. Gallie,et al. Mechanisms of loss of heterozygosity in retinoblastoma. , 1992, Cytogenetics and cell genetics.
[71] J. O'Brien,et al. A transgenic mouse model for trilateral retinoblastoma. , 1990, Archives of ophthalmology.
[72] A. Balmain,et al. Genetic changes in skin tumor progression: Correlation between presence of a mutant ras gene and loss of heterozygosity on mouse chromosome 7 , 1990, Cell.
[73] Daniel M. Albert,et al. Retinoblastoma in transgenic mice , 1990, Nature.
[74] Stephen H. Friend,et al. A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma , 1986, Nature.
[75] R. W. Young. Cell proliferation during postnatal development of the retina in the mouse. , 1985, Brain research.
[76] R. W. Young. Cell differentiation in the retina of the mouse , 1985, The Anatomical record.
[77] B. Gallie,et al. Genetic origin of mutations predisposing to retinoblastoma. , 1985, Science.
[78] Robert C. Wolpert,et al. A Review of the , 1985 .
[79] A. Knudson. Mutation and cancer: statistical study of retinoblastoma. , 1971, Proceedings of the National Academy of Sciences of the United States of America.