Identification of the Shiga Toxin-Producing Escherichia coli O104:H4 Strain Responsible for a Food Poisoning Outbreak in Germany by PCR

An outbreak caused by Escherichia coli serotype O104:H4 strains has been affecting northern Germany since May 2011, with 3,222 patients infected and 39 of them dead by 18 June ([4][1]). Around 25% of the patients developed hemolytic-uremic syndrome (HUS) ([1][2], [3][3]), a rate which is much higher

[1]  Klaus Stark,et al.  Epidemic profile of Shiga-toxin-producing Escherichia coli O104:H4 outbreak in Germany. , 2011, The New England journal of medicine.

[2]  G Krause,et al.  Large and ongoing outbreak of haemolytic uraemic syndrome, Germany, May 2011. , 2011, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.

[3]  S. Cutillo [Hemolytic-uremic syndrome]. , 1973, La Pediatria.

[4]  J. Cowden,et al.  Escherichia coli O157 Infection and Secondary Spread, Scotland, 1999–2008 , 2011, Emerging infectious diseases.

[5]  David L. Swerdlow,et al.  Epidemiology of Escherichia coli O157:H7 Outbreaks, United States, 1982–2002 , 2005, Emerging infectious diseases.

[6]  Harry L. T. Mobley,et al.  Pathogenic Escherichia coli , 2004, Nature Reviews Microbiology.

[7]  A. Gilsdorf,et al.  Update on the ongoing outbreak of haemolytic uraemic syndrome due to Shiga toxin-producing Escherichia coli (STEC) serotype O104, Germany, May 2011. , 2011, Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin.