Cut-off values of serum growth hormone (GH) in pharmacological stimulation tests (PhT) evaluated in short-statured children using a chemiluminescent immunometric assay (ICMA) calibrated with the International Recombinant Human GH Standard 98/574

Hospital de Pediatr i a Prof. Dr. Juan P. Garrahan, Combate de los Pozos 1881, Ciudad Autonoma de Buenos Aires, CP 1245, Argentina, Phone: +54 11 43084300, Fax: +54 11 43086700, mE- ail: echaler@yahoo.com Juan M. Lazzati, Mercedes Maceiras, Marco A. Rivarola and Alicia Belgorosky: Hospital de Pediatr i a Prof. Dr. Juan P. Garrahan , Buenos Aires , Argentina Gabriela Ballerini, Mauro Frusti, Ignacio Bergada and Gabriela Ropelato: Hospital de Ni n os Ricardo Gutierrez , Buenos Aires , Argentina

[1]  C. Carrozza,et al.  Human growth hormone (GH) immunoassay: standardization and clinical implications , 2011, Clinical Chemistry and Laboratory Medicine.

[2]  P. Cohen,et al.  Consensus statement on the diagnosis and treatment of children with idiopathic short stature: a summary of the Growth Hormone Research Society, the Lawson Wilkins Pediatric Endocrine Society, and the European Society for Paediatric Endocrinology Workshop. , 2008, The Journal of clinical endocrinology and metabolism.

[3]  M. Sheppard.  Growth hormone assay standardization: an important clinical advance , 2007, Clinical endocrinology.

[4]  A. Belgorosky,et al.  Differences in Serum GH Cut-Off Values for Pharmacological Tests of GH Secretion Depend on the Serum GH Method , 2006, Hormone Research in Paediatrics.

[5]  G. Baumann,et al.  Laboratory measurement of growth hormone. , 2004, Clinica chimica acta; international journal of clinical chemistry.

[6]  A. Belgorosky,et al.  Between-assay differences in serum growth hormone (GH) measurements: importance in the diagnosis of GH deficiency in childhood. , 2001, Clinical chemistry.

[7]  P. Wood,et al.  Growth Hormone: Its Measurement and the Need for Assay Harmonization , 2001, Annals of clinical biochemistry.

[8]  Growth Hormone Research Society,,et al.  Consensus Guidelines for the Diagnosis and Treatment of Growth Hormone (GH) Deficiency in Childhood and Adolescence: Summary Statement of the GH Research Society , 2001 .

[9]  J. Heinrich,et al.  Estrogen priming effect on growth hormone (GH) provocative test: a useful tool for the diagnosis of GH deficiency. , 2000, The Journal of clinical endocrinology and metabolism.

[10]  P. H. Petersen,et al.  Evaluation of growth hormone assays using ratio plots. , 1998, Clinical chemistry.

[11]  G. Baumann.  Growth hormone heterogeneity: genes, isohormones, variants, and binding proteins. , 1991, Endocrine reviews.