Interleukin-17A contributes to atrial fibrillation recurrence and left atrial reservoir function after catheter ablation.

432 Patients with no symptomatic AF recurrence or ir‐ regular pulse and those requiring no antiarrhyth‐ mic agent after the blanking period were assigned into the “no ‐recurrence group.” Patients with AF recurrence were assigned to the “AF ‐recurrence group.” Blood samples were taken from patients on the morning of CA (at 6:00 AM), the next day after CA, 3 months, 6 months, 12 months af‐ ter CA, and following symptom recurrence. Se‐ rum levels of IL ‐17A, N ‐terminal fragment of the prohormone brain natriuretic peptide (NT‐ ‐proBNP), matrix metallopeptidase 9 (MMP‐ ‐9), procollagen type I, and procollagen type III were measured using a commercial biotin–avi‐ din based sandwich enzyme ‐linked immunosor‐ bent assay (eBiosciences, San Diego, California, United States).

[1]  D. Kosior,et al.  Functional status with rhythm- versus rate-control strategy for persistent atrial fibrillation. , 2018, Polish archives of internal medicine.

[2]  D. Lin,et al.  Postoperative atrial tachycardias after mitral valve surgery: Mechanisms and outcomes of catheter ablation. , 2017, Heart rhythm.

[3]  Maoqin Shu,et al.  Elevated plasma levels of Th17-related cytokines are associated with increased risk of atrial fibrillation , 2016, Scientific Reports.

[4]  P. Bruneval,et al.  TREM-1 Mediates Inflammatory Injury and Cardiac Remodeling Following Myocardial Infarction. , 2015, Circulation research.

[5]  Hiroshi Ashikaga,et al.  Association of left atrial function and left atrial enhancement in patients with atrial fibrillation: cardiac magnetic resonance study. , 2015, Circulation. Cardiovascular imaging.

[6]  S. Heymans,et al.  Myocardial Extracellular Matrix: An Ever-Changing and Diverse Entity , 2014, Circulation research.

[7]  Xinyang Song,et al.  IL-17 family cytokines mediated signaling in the pathogenesis of inflammatory diseases. , 2013, Cellular signalling.

[8]  M. Allessie,et al.  Post-operative atrial fibrillation: a maze of mechanisms , 2011, Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology.

[9]  P. Sengupta,et al.  Left atrial reservoir function predicts atrial fibrillation recurrence after catheter ablation: a two-dimensional speckle strain study , 2011, Journal of Interventional Cardiac Electrophysiology.

[10]  S. Nakae,et al.  Functional specialization of interleukin-17 family members. , 2011, Immunity.

[11]  B. Hoit.  Assessing atrial mechanical remodeling and its consequences. , 2005, Circulation.