The efficient development of low permeability reservoir exploration and development at home and abroad has been a difficult and hot issues. Changqing Oilfield is the permeability, low pressure, low abundance of the "three low" oil and gas fields, is the world famous low permeability. In recent years, with the low permeability of Changqing Oilfield fast on the scale of production, development and gradually increase the difficulty, well production decreased year by year, oil layers, layer contradictions become increasingly prominent. Changqing Oilfield how old stable production, it will be a challenging task. In this paper, Changqing Oilfield per 214 Jiyuan Chang 4 +5 reservoir, for example, focuses on the reservoir of the reservoir by strengthening fine management and implement water policies, improve water technical control, good water injection, inject enough water, improve the capacity of the reservoir stable production, improve development effectiveness.