Technological advances define shifting pathway signaling from normal to primary and metastatic colorectal cancer
暂无分享,去创建一个
[1] W. Wu,et al. Cancer‐associated fibroblasts potentiate colorectal cancer progression by crosstalk of the IGF2–IGF1R and Hippo–YAP1 signaling pathways , 2022, The Journal of pathology.
[2] C. Conrad,et al. Patient-specific modeling of stroma-mediated chemoresistance of pancreatic cancer using a three-dimensional organoid-fibroblast co-culture system , 2022, Journal of Experimental & Clinical Cancer Research.
[3] Joshua D. Greenlee,et al. A syngeneic MC38 orthotopic mouse model of colorectal cancer metastasis , 2022, Biology methods & protocols.
[4] S. Prabhakar,et al. Single-cell and bulk transcriptome sequencing identifies two epithelial tumor cell states and refines the consensus molecular classification of colorectal cancer , 2022, Nature Genetics.
[5] Seung Ah Lee,et al. Modeling Pancreatic Cancer with Patient-Derived Organoids Integrating Cancer-Associated Fibroblasts , 2022, Cancers.
[6] T. Benoukraf,et al. Hepatocellular carcinoma organoid co-cultures mimic angiocrine crosstalk to generate inflammatory tumor microenvironment. , 2022, Biomaterials.
[7] B. Mroczko,et al. Relationship between VEGF Family Members, Their Receptors and Cell Death in the Neoplastic Transformation of Colorectal Cancer , 2022, International journal of molecular sciences.
[8] F. Hollande,et al. Longitudinal Monitoring of Intra-Tumoural Heterogeneity Using Optical Barcoding of Patient-Derived Colorectal Tumour Models , 2022, Cancers.
[9] Paige N. Vega,et al. Differential pre-malignant programs and microenvironment chart distinct paths to malignancy in human colorectal polyps , 2021, Cell.
[10] F. Lordick,et al. Primary and metastatic peritoneal surface malignancies , 2021, Nature Reviews Disease Primers.
[11] M. Michael,et al. Organoids as a Robust Preclinical Model for Precision Medicine in Colorectal Cancer: A Systematic Review , 2021, Annals of Surgical Oncology.
[12] Zhonghang Xu,et al. TGF-beta signaling in cancer radiotherapy. , 2021, Cytokine.
[13] Chin Wee Tan,et al. Low-viscosity matrix suspension culture enables scalable analysis of patient-derived organoids and tumoroids from the large intestine , 2021, Communications Biology.
[14] M. Hahne,et al. The Role of Cancer-Associated Fibroblasts in Cancer Invasion and Metastasis , 2021, Cancers.
[15] J. Hogenesch,et al. The Circadian Clock Gene, Bmal1, Regulates Intestinal Stem Cell Signaling and Represses Tumor Initiation , 2021, Cellular and molecular gastroenterology and hepatology.
[16] R. Ramsay,et al. Shifting the treatment paradigm for patients with deficient mismatch repair colon cancer: is there a role for immunotherapy? , 2021, ANZ journal of surgery.
[17] J. Subramanian,et al. Refining colorectal cancer classification and clinical stratification through a single-cell atlas , 2021, bioRxiv.
[18] T. Seidle,et al. Patient-Derived Xenograft vs. Organoids: A Preliminary Analysis of Cancer Research Output, Funding and Human Health Impact in 2014–2019 , 2020, Animals : an open access journal from MDPI.
[19] Jie Cao,et al. Mutations in the notch signalling pathway are associated with enhanced anti‐tumour immunity in colorectal cancer , 2020, Journal of cellular and molecular medicine.
[20] F. Greten,et al. AKT-dependent NOTCH3 activation drives tumor progression in a model of mesenchymal colorectal cancer , 2020, The Journal of experimental medicine.
[21] A. Bennaceur-Griscelli,et al. Chronic circadian disruption modulates breast cancer stemness and immune microenvironment to drive metastasis in mice , 2020, Nature Communications.
[22] Andrew E. Rosselot,et al. Ontogeny and function of the circadian clock in intestinal organoids , 2020, bioRxiv.
[23] O. De Wever,et al. Targeting the Tumor Microenvironment in Colorectal Peritoneal Metastases. , 2020, Trends in cancer.
[24] J. Bienkowska,et al. Comparison of the molecular and cellular phenotypes of common mouse syngeneic models with human tumors , 2020, BMC Genomics.
[25] T. Schumacher,et al. Tumor organoid–T-cell coculture systems , 2019, Nature Protocols.
[26] Qin Li,et al. Cancer-Associated Fibroblasts Promote Angiogenesis of Hepatocellular Carcinoma by VEGF-Mediated EZH2/VASH1 Pathway , 2019, Technology in cancer research & treatment.
[27] W. Roth,et al. Ex vivo tissue slice culture system to measure drug-response rates of hepatic metastatic colorectal cancer , 2019, BMC Cancer.
[28] W. Scheithauer,et al. Consensus molecular subgroups (CMS) of colorectal cancer (CRC) and first-line efficacy of FOLFIRI plus cetuximab or bevacizumab in the FIRE3 (AIO KRK-0306) trial , 2019, Annals of oncology : official journal of the European Society for Medical Oncology.
[29] E. Cuppen,et al. Patient-derived organoids can predict response to chemotherapy in metastatic colorectal cancer patients , 2019, Science Translational Medicine.
[30] Jessica A Lavery,et al. A rectal cancer organoid platform to study individual responses to chemoradiation , 2019, Nature Medicine.
[31] Satchidananda Panda,et al. Interplay between Circadian Clock and Cancer: New Frontiers for Cancer Treatment. , 2019, Trends in cancer.
[32] G. Fontanini,et al. Primary tumor sidedness and benefit from FOLFOXIRI plus bevacizumab as initial therapy for metastatic colorectal cancer. Retrospective analysis of the TRIBE trial by GONO , 2018, Annals of oncology : official journal of the European Society for Medical Oncology.
[33] R. Steuer,et al. The Circadian Clock Regulates Metabolic Phenotype Rewiring Via HKDC1 and Modulates Tumor Progression and Drug Response in Colorectal Cancer , 2018, EBioMedicine.
[34] Pornpimol Charoentong,et al. Targeting immune checkpoints potentiates immunoediting and changes the dynamics of tumor evolution , 2018, Nature Communications.
[35] I. B. Borel Rinkes,et al. Histopathological and molecular classification of colorectal cancer and corresponding peritoneal metastases , 2018, The British journal of surgery.
[36] E. Voest,et al. Tumor Organoids as a Pre-clinical Cancer Model for Drug Discovery. , 2017, Cell chemical biology.
[37] J. Pignon,et al. Prognostic and predictive value of primary tumour side in patients with RAS wild-type metastatic colorectal cancer treated with chemotherapy and EGFR directed antibodies in six randomized trials † , 2017, Annals of oncology : official journal of the European Society for Medical Oncology.
[38] Toshiro Sato,et al. Defining the role of Lgr5+ stem cells in colorectal cancer: from basic research to clinical applications , 2017, Genome Medicine.
[39] R. Lothe,et al. Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies , 2017, Molecular Cancer.
[40] I. B. Borel Rinkes,et al. Neoadjuvant chemotherapy affects molecular classification of colorectal tumors , 2017, Oncogenesis.
[41] S. Kopetz,et al. Recent developments in the treatment of metastatic colorectal cancer , 2017, Therapeutic advances in medical oncology.
[42] R. Nusse,et al. Wnt/β-Catenin Signaling, Disease, and Emerging Therapeutic Modalities , 2017, Cell.
[43] B. Leggett,et al. Genetic editing of colonic organoids provides a molecularly distinct and orthotopic preclinical model of serrated carcinogenesis , 2017, Gut.
[44] L. J. K. Wee,et al. Reference component analysis of single-cell transcriptomes elucidates cellular heterogeneity in human colorectal tumors , 2017, Nature Genetics.
[45] W. Frankel,et al. Molecular genetics of microsatellite-unstable colorectal cancer for pathologists , 2017, Diagnostic Pathology.
[46] Y. Tomita,et al. p53 functional deficiency in human colon cancer cells promotes fibroblast-mediated angiogenesis and tumor growth. , 2016, Carcinogenesis.
[47] Cord Langner,et al. MUC1, MUC2, MUC5AC, and MUC6 in colorectal cancer: expression profiles and clinical significance , 2016, Virchows Archiv.
[48] Toshio Uraoka,et al. A Colorectal Tumor Organoid Library Demonstrates Progressive Loss of Niche Factor Requirements during Tumorigenesis. , 2016, Cell stem cell.
[49] M. Katoh. FGFR inhibitors: Effects on cancer cells, tumor microenvironment and whole-body homeostasis (Review) , 2016, International journal of molecular medicine.
[50] Jeffrey S. Morris,et al. The Consensus Molecular Subtypes of Colorectal Cancer , 2015, Nature Medicine.
[51] J. Malaterre,et al. Intestinal-specific activatable Myb initiates colon tumorigenesis in mice , 2015, Oncogene.
[52] Hans Clevers,et al. SnapShot: Growing Organoids from Stem Cells , 2015, Cell.
[53] N. Nagarajan,et al. Cloning and Variation of Ground State Intestinal Stem Cells , 2015, Nature.
[54] Hayley E. Francies,et al. Prospective Derivation of a Living Organoid Biobank of Colorectal Cancer Patients , 2015, Cell.
[55] Hans Clevers,et al. Sequential cancer mutations in cultured human intestinal stem cells , 2015, Nature.
[56] J. Malaterre,et al. Peritoneal Tumorigenesis and Inflammation are Ameliorated by Humidified-Warm Carbon Dioxide Insufflation in the Mouse , 2015, Annals of Surgical Oncology.
[57] R. Tothill,et al. Cohesin Rad21 mediates loss of heterozygosity and is upregulated via Wnt promoting transcriptional dysregulation in gastrointestinal tumors. , 2014, Cell reports.
[58] J. Malaterre,et al. Tripartite interactions between Wnt signaling, Notch and Myb for stem/progenitor cell functions during intestinal tumorigenesis. , 2014, Stem cell research.
[59] J. Castle,et al. Immunomic, genomic and transcriptomic characterization of CT26 colorectal carcinoma , 2014, BMC Genomics.
[60] Jens T Siveke,et al. EGF receptor is required for KRAS-induced pancreatic tumorigenesis. , 2012, Cancer cell.
[61] J. Malaterre,et al. Myb Controls Intestinal Stem Cell Genes and Self‐Renewal , 2011, Stem cells.
[62] Hans Clevers,et al. Long-term expansion of epithelial organoids from human colon, adenoma, adenocarcinoma, and Barrett's epithelium. , 2011, Gastroenterology.
[63] Hans Clevers,et al. Paneth cells constitute the niche for Lgr5 stem cells in intestinal crypts , 2011, Nature.
[64] S. Artavanis-Tsakonas,et al. Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine , 2009, Proceedings of the National Academy of Sciences.
[65] P. Darcy,et al. Frizzled-7 dictates three-dimensional organization of colorectal cancer cell carcinoids , 2007, Oncogene.
[66] H. Clevers,et al. c-Myb is required for progenitor cell homeostasis in colonic crypts , 2007, Proceedings of the National Academy of Sciences.
[67] Takeshi Oshima,et al. Mitogenic Influence of Human R-Spondin1 on the Intestinal Epithelium , 2005, Science.
[68] Andrew P. Weng,et al. Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia , 2004, Science.
[69] B. Iacopetta. Are there two sides to colorectal cancer? , 2002, International journal of cancer.
[70] A. Dignass,et al. Peptide growth factors in the intestine. , 2001, European journal of gastroenterology & hepatology.
[71] R. Ramsay,et al. c-Myb is critical for murine colon development , 1999, Oncogene.
[72] Hans Clevers,et al. Consensus molecular subtypes of colorectal cancer are recapitulated in in vitro and in vivo models , 2017, Cell Death & Differentiation.