Inhibiting glucosylceramide synthase facilitates the radiosensitizing effects of vinorelbine in lung adenocarcinoma cells.
暂无分享,去创建一个
W. Su | Chiou-Feng Lin | Jang-Yang Chang | Chia-Ling Chen | H. Chen | W. Chiu | Chia-Ling Li | Sheng-jie Luo
[1] Helen H. W. Chen,et al. Oral vinorelbine: a Better Choice for Concurrent Chemoradiotherapy in Stage III Non-Small Cell Lung Cancer , 2012 .
[2] W. Su,et al. Vinca alkaloids cause aberrant ROS-mediated JNK activation, Mcl-1 downregulation, DNA damage, mitochondrial dysfunction, and apoptosis in lung adenocarcinoma cells. , 2012, Biochemical pharmacology.
[3] G. Videtic. Locally advanced non–small cell lung cancer: What is the optimal concurrent chemoradiation regimen? , 2012, Cleveland Clinic Journal of Medicine.
[4] K. Kaira,et al. Phase I results of vinorelbine with concurrent radiotherapy in elderly patients with unresectable, locally advanced non-small-cell lung cancer: West Japan Thoracic Oncology Group (WJTOG3005-DI). , 2012, International journal of radiation oncology, biology, physics.
[5] Yee‐Shin Lin,et al. Glucosylceramide synthase inhibitor PDMP sensitizes chronic myeloid leukemia T315I mutant to Bcr‐Abl inhibitor and cooperatively induces glycogen synthase kinase‐3‐regulated apoptosis , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[6] M. Provencio,et al. Inoperable stage III non-small cell lung cancer: Current treatment and role of vinorelbine. , 2011, Journal of thoracic disease.
[7] Yee‐Shin Lin,et al. Apoptotic Sphingolipid Ceramide in Cancer Therapy , 2011, Journal of lipids.
[8] W. Curran,et al. Combined modality therapy for stage III non-small-cell lung cancer. , 2010, Seminars in radiation oncology.
[9] Jing Yi,et al. Cancer cell killing via ROS: To increase or decrease, that is the question , 2008, Cancer biology & therapy.
[10] J. Vermorken,et al. Comparative study of the radiosensitising and cell cycle effects of vinflunine and vinorelbine, in vitro , 2008, BMC Cancer.
[11] Joseph K Salama,et al. The concurrent chemoradiation paradigm—general principles , 2007, Nature Clinical Practice Oncology.
[12] M. Socinski,et al. Combined modality therapy for stage III non-small cell lung cancer. , 2006, The oncologist.
[13] Chiou-Feng Lin,et al. Ceramide in apoptotic signaling and anticancer therapy. , 2006, Current medicinal chemistry.
[14] R. Fietkau,et al. Oral Vinorelbine and Cisplatin with Concomitant Radiotherapy in Stage III Non-Small Cell Lung Cancer (NSCLC): A Feasibility Study , 2006, Oncology Research and Treatment.
[15] D. Galetta,et al. Multimodality treatment of unresectable stage III non-small cell lung cancer: interim analysis of a phase II trial with preoperative gemcitabine and concurrent radiotherapy. , 2006, The Journal of thoracic and cardiovascular surgery.
[16] S. Kurinna,et al. Ceramide Promotes Apoptosis in Lung Cancer-Derived A549 Cells by a Mechanism Involving c-Jun NH2-Terminal Kinase , 2004, Cancer Research.
[17] S. Clarke,et al. Radiosensitization of vinorelbine and gemcitabine in NCI-H460 non-small-cell lung cancer cells. , 2004, International journal of radiation oncology, biology, physics.
[18] R. Schmidt‐Ullrich. Molecular targets in radiation oncology , 2003, Oncogene.
[19] P. Ruvolo. Intracellular signal transduction pathways activated by ceramide and its metabolites. , 2003, Pharmacological research.
[20] T. Araki,et al. Concurrent two-dimensional radiotherapy and weekly docetaxel in the treatment of stage III non-small cell lung cancer: a good local response but no good survival due to radiation pneumonitis. , 2003, Lung cancer.
[21] H. Ichijo,et al. Phosphorylation and Inactivation of Myeloid Cell Leukemia 1 by JNK in Response to Oxidative Stress* , 2002, The Journal of Biological Chemistry.
[22] J. Usuda,et al. Mechanism of vinorelbine-induced radiosensitization of human small cell lung cancer cells , 2002, Cancer Chemotherapy and Pharmacology.
[23] J. Usuda,et al. Mechanism of the radiosensitization induced by vinorelbine in human non-small cell lung cancer cells. , 2001, Lung cancer.
[24] T Takahashi,et al. ASK1 is required for sustained activations of JNK/p38 MAP kinases and apoptosis , 2001, EMBO reports.
[25] A. Giuliano,et al. Ceramide glycosylation potentiates cellular multidrug resistance , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[26] B. Hill,et al. Novel actions of the antitumor drugs vinflunine and vinorelbine on microtubules. , 2000, Cancer research.
[27] W. Curran,et al. Final Results of Phase III Trial in Regionally Advanced Unresectable Non-Small Cell Lung Cancer : Radiation Therapy Oncology Group, Eastern Cooperative Oncology Group, and Southwest Oncology Group , 2000 .
[28] T. Chambers,et al. Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells. , 2000, Experimental cell research.
[29] J. Herndon,et al. Improved survival in stage III non-small-cell lung cancer: seven-year follow-up of cancer and leukemia group B (CALGB) 8433 trial. , 1996, Journal of the National Cancer Institute.
[30] M. Edelstein,et al. Potentiation of radiation therapy by vinorelbine (Navelbine) in non-small cell lung cancer. , 1996, Seminars in oncology.
[31] K. Scotto,et al. Ceramide synthase mediates daunorubicin-induced apoptosis: An alternative mechanism for generating death signals , 1995, Cell.
[32] B. Jeremic,et al. Randomized trial of hyperfractionated radiation therapy with or without concurrent chemotherapy for stage III non-small-cell lung cancer. , 1995, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[33] H. Burris,et al. Summary of data from in vitro and phase I vinorelbine (Navelbine) studies. , 1994, Seminars in oncology.
[34] Y. Hannun,et al. Programmed cell death induced by ceramide. , 1993, Science.
[35] G. van Kaick,et al. New aspects in the staging of lung cancer. Prospective validation of the international union against cancer TNM classification , 1992, Cancer.
[36] H. Bartelink,et al. Effects of concomitant cisplatin and radiotherapy on inoperable non-small-cell lung cancer. , 1992, The New England journal of medicine.
[37] A. Jemal,et al. Cancer statistics, 2012 , 2012, CA: a cancer journal for clinicians.
[38] L. Schwartz,et al. New response evaluation criteria in solid tumours: revised RECIST guideline (version 1.1). , 2009, European journal of cancer.
[39] A. Dueñas-González,et al. Radiation Oncology BioMed Central Review Radiosensitizers in cervical cancer. Cisplatin and beyond , 2006 .