Near infrared spectrometer combined with multichannel EEG for functional brain imaging

Clinical conditions such as epilepsy and stroke could benefit from portable functional brain evaluation systems for continuous online monitoring and to assist diagnostic. The combination of electroencephalography (EEG) and near infrared spectroscopy (NIRS) has the potential to provide useful information towards that task. Recent attempts at their combination in a single device have shown beneficial results but available instruments lack NIRS sensitivity and have low channel number. In this work, a portable EEG-NIRS prototype is developed having a large channel count to cover the whole head and a high NIRS sensitivity is obtained by the use of avalanche photodiodes. The system is demonstrated to be portable and its power consumption enables battery operation over long periods for continuous monitoring.

[1]  S. Rauch,et al.  Near-infrared spectroscopy and imaging for investigating stroke rehabilitation: test-retest reliability and review of the literature. , 2006, Archives of physical medicine and rehabilitation.

[2]  Reinhard Grebe,et al.  NIRS‐measured oxy‐ and deoxyhemoglobin changes associated with EEG spike‐and‐wave discharges in children , 2008, Epilepsia.

[3]  Masashi Kiguchi,et al.  Development of wearable optical topography system for mapping the prefrontal cortex activation. , 2009, The Review of scientific instruments.

[4]  C. Grova,et al.  Non-invasive pre-surgical investigation of a 10 year-old epileptic boy using simultaneous EEG–NIRS , 2008, Seizure.

[5]  A. Rosen,et al.  A portable near infrared spectroscopy system for bedside monitoring of newborn brain , 2005, Biomedical engineering online.

[6]  Esther Rodriguez-Villegas,et al.  Wearable Electroencephalography , 2010, IEEE Engineering in Medicine and Biology Magazine.

[7]  Martin Wolf,et al.  Progress of near-infrared spectroscopy and topography for brain and muscle clinical applications. , 2007, Journal of biomedical optics.

[8]  A. Maki,et al.  Wavelength Dependence of Effective Pathlength Factor in Noninvasive Optical Measurements of Human Brain Functions , 2006 .

[9]  Luigi Rovati,et al.  Optical and electrical recording of neural activity evoked by graded contrast visual stimulus , 2007, Biomedical engineering online.

[10]  Franco Lepore,et al.  Non-invasive alternatives to the Wada test in the presurgical evaluation of language and memory functions in epilepsy patients. , 2007, Epileptic disorders : international epilepsy journal with videotape.