Inhibition of TIMP1 enhances angiogenesis in vivo and cell migration in vitro.

[1]  Juan P. Albar,et al.  Membrane Type 1-Matrix Metalloproteinase Is Activated during Migration of Human Endothelial Cells and Modulates Endothelial Motility and Matrix Remodeling* , 2001, The Journal of Biological Chemistry.

[2]  M. Stack,et al.  Functional Interplay between Type I Collagen and Cell Surface Matrix Metalloproteinase Activity* , 2001, The Journal of Biological Chemistry.

[3]  W. Stetler-Stevenson,et al.  Tissue inhibitor of metalloproteinase-1 alters the tumorigenicity of Burkitt's lymphoma via divergent effects on tumor growth and angiogenesis. , 2001, The American journal of pathology.

[4]  W. Stetler-Stevenson,et al.  Proteases in invasion: matrix metalloproteinases. , 2001, Seminars in cancer biology.

[5]  M. Reed,et al.  A deficit in collagenase activity contributes to impaired migration of aged microvascular endothelial cells , 2000, Journal of cellular biochemistry.

[6]  K. Brew,et al.  Tissue inhibitors of metalloproteinases: evolution, structure and function. , 2000, Biochimica et biophysica acta.

[7]  L. Smilenov,et al.  Focal adhesion motility revealed in stationary fibroblasts. , 1999, Science.

[8]  J. Parsons,et al.  Cell Migration--Movin' On , 1999, Science.

[9]  A. Singer,et al.  Cutaneous wound healing. , 1999, The New England journal of medicine.

[10]  W. Parks,et al.  Role of Matrix Metalloproteinases and Their Inhibition in Cutaneous Wound Healing and Allergic Contact Hypersensitivity , 1999, Annals of the New York Academy of Sciences.

[11]  P. Henriet,et al.  Tissue inhibitors of metalloproteinases (TEMP) in invasion and proliferation , 1999, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.

[12]  C. López-Otín,et al.  Induction of Collagenase-3 (MMP-13) Expression in Human Skin Fibroblasts by Three-dimensional Collagen Is Mediated by p38 Mitogen-activated Protein Kinase* , 1999, The Journal of Biological Chemistry.

[13]  M. d’Ortho,et al.  Role of collagenase in mediating in vitro alveolar epithelial wound repair. , 1999, Journal of cell science.

[14]  D. Gomez,et al.  Histopathological findings in a highly invasive mouse mammary carcinoma transfected with human tissue inhibitor of metalloproteinases-1. , 1998, Oncology reports.

[15]  Richard O. Hynes,et al.  Integrin-mediated Signals Regulated by Members of the Rho Family of GTPases , 1998, The Journal of cell biology.

[16]  C. López-Otín,et al.  Differential Effects of Transforming Growth Factor-β on the Expression of Collagenase-1 and Collagenase-3 in Human Fibroblasts* , 1998, The Journal of Biological Chemistry.

[17]  M. Nomizu,et al.  Activation of β1 Integrin Signaling Stimulates Tyrosine Phosphorylation of p190 RhoGAP and Membrane-protrusive Activities at Invadopodia* , 1998, The Journal of Biological Chemistry.

[18]  A. Strongin,et al.  Matrix metalloproteinase-2 activation modulates glioma cell migration. , 1997, Journal of cell science.

[19]  C. Jackson,et al.  Human microvascular endothelial cells differ from macrovascular endothelial cells in their expression of matrix metalloproteinases. , 1997, The international journal of biochemistry & cell biology.

[20]  G. Giannelli,et al.  Induction of cell migration by matrix metalloprotease-2 cleavage of laminin-5. , 1997, Science.

[21]  S. Krane,et al.  The Activity of Collagenase-1 Is Required for Keratinocyte Migration on a Type I Collagen Matrix , 1997, The Journal of cell biology.

[22]  P. Angel,et al.  The catalytic domain of activated collagenase I (MMP-1) is absolutely required for interaction with its specific inhibitor, tissue inhibitor of metalloproteinases-1 (TIMP-1). , 1997, European journal of biochemistry.

[23]  K. Taylor,et al.  The Mechanism of Inhibition of Collagenase by TIMP-1* , 1996, The Journal of Biological Chemistry.

[24]  D. Gomez,et al.  Breast cancer; tumor neovasculature and the effect of tissue inhibitor of metalloproteinases-1 (TIMP-1) on angiogenesis. , 1996, In vivo.

[25]  K. Geoghegan,et al.  Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage. , 1996, The Journal of clinical investigation.

[26]  C. López-Otín,et al.  Biochemical Characterization of Human Collagenase-3 (*) , 1996, The Journal of Biological Chemistry.

[27]  N. Bersch,et al.  Metalloproteinase inhibition and erythroid potentiation are independent activities of tissue inhibitor of metalloproteinases-1. , 1995, Blood.

[28]  L. Cornelius,et al.  Human dermal microvascular endothelial cells produce matrix metalloproteinases in response to angiogenic factors and migration. , 1995, The Journal of investigative dermatology.

[29]  H. Birkedal‐Hansen,et al.  Functional domains of human TIMP-1 (tissue inhibitor of metalloproteinases). , 1994, The Journal of biological chemistry.

[30]  Mark D. Johnson,et al.  Inhibition of angiogenesis by tissue inhibitor of metalloproteinase , 1994, Journal of cellular physiology.

[31]  T. Hayakawa,et al.  Tissue inhibitors of metalloproteinases and their cell growth-promoting activity. , 1994, Cell structure and function.

[32]  R. Poorman,et al.  Interstitial collagenase is required for angiogenesis in vitro. , 1994, Developmental biology.

[33]  V. V. van Hinsbergh,et al.  Regulation of matrix metalloproteinase expression in human vein and microvascular endothelial cells. Effects of tumour necrosis factor alpha, interleukin 1 and phorbol ester. , 1993, The Biochemical journal.

[34]  J. Olerud,et al.  Cell-matrix interactions modulate interstitial collagenase expression by human keratinocytes actively involved in wound healing. , 1993, The Journal of clinical investigation.

[35]  P. Henriet,et al.  Cloning and sequencing of mouse collagenase cDNA Divergence of mouse and rat collagenases from the other mammalian collagenases , 1992, FEBS letters.

[36]  L. F. Fajardo,et al.  The disc angiogenesis system. , 1988, Laboratory investigation; a journal of technical methods and pathology.

[37]  M. Klagsbrun,et al.  Accelerated wound repair, cell proliferation, and collagen accumulation are produced by a cartilage-derived growth factor , 1985, The Journal of cell biology.

[38]  M. Reed,et al.  Neovascularization in aged mice: delayed angiogenesis is coincident with decreased levels of transforming growth factor beta1 and type I collagen. , 1998, The American journal of pathology.