Somatic mutations in DROSHA and DICER1 impair microRNA biogenesis through distinct mechanisms in Wilms tumours
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Dinesh Rakheja | James S. Malter | Nitin J. Karandikar | Vanessa Schmid | Tsung-Cheng Chang | Joshua T. Mendell | Abhay A. Shukla | Tsung-Cheng Chang | J. Mendell | D. Rakheja | A. Shukla | J. Malter | N. Karandikar | J. Amatruda | Shama K Khokhar | Yangjian Liu | James F. Amatruda | Kenneth S. Chen | Shama Khokhar | Jonathan E. Wickiser | Yangjian Liu | Vanessa Schmid | J. Wickiser
[1] Kristian Cibulskis,et al. A remarkably simple genome underlies highly malignant pediatric rhabdoid cancers. , 2012, The Journal of clinical investigation.
[2] Jill P. Mesirov,et al. MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS , 2012, Nature.
[3] T. Tuschl,et al. The Human DiGeorge Syndrome Critical Region Gene 8 and Its D. melanogaster Homolog Are Required for miRNA Biogenesis , 2004, Current Biology.
[4] Arjun Bhutkar,et al. In vivo structure-function analysis of human Dicer reveals directional processing of precursor miRNAs. , 2012, RNA.
[5] Piero Carninci,et al. Site-specific DICER and DROSHA RNA products control the DNA damage response , 2012, Nature.
[6] Drena Dobbs,et al. ZiFiT (Zinc Finger Targeter): an updated zinc finger engineering tool , 2010, Nucleic Acids Res..
[7] V. Kim,et al. The role of PACT in the RNA silencing pathway , 2006, The EMBO journal.
[8] W. Foulkes,et al. miRNA Processing and Human Cancer: DICER1 Cuts the Mustard , 2011, Science Translational Medicine.
[9] A. Ashworth,et al. Molecular profiling reveals frequent gain of MYCN and anaplasia‐specific loss of 4q and 14q in wilms tumor , 2011, Genes, chromosomes & cancer.
[10] A. Nicholson,et al. DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome , 2011, Journal of Medical Genetics.
[11] F. Alt,et al. Enhanced expression of the N-myc gene in Wilms' tumors. , 1986, Cancer research.
[12] V. Huff,et al. Wilms tumor genetics: Mutations in WT1, WTX, and CTNNB1 account for only about one‐third of tumors , 2008, Genes, chromosomes & cancer.
[13] F. Slack,et al. let-7 microRNAs in development, stem cells and cancer. , 2008, Trends in molecular medicine.
[14] Steven J. M. Jones,et al. The genetic landscape of high-risk neuroblastoma , 2013, Nature Genetics.
[15] R. Siebert,et al. Nonsense mutation and inactivation of SMARCA4 (BRG1) in an atypical teratoid/rhabdoid tumor showing retained SMARCB1 (INI1) expression. , 2011, The American journal of surgical pathology.
[16] Elaine R. Mardis,et al. Novel mutations target distinct subgroups of medulloblastoma , 2012, Nature.
[17] D. Court,et al. Crystallographic and modeling studies of RNase III suggest a mechanism for double-stranded RNA cleavage. , 2001, Structure.
[18] P. Brennan,et al. Wilms' tumour: a systematic review of risk factors and meta-analysis. , 2010, Paediatric and perinatal epidemiology.
[19] J. Keith Joung,et al. Targeted gene disruption in somatic zebrafish cells using engineered TALENs , 2011, Nature Biotechnology.
[20] G. Daley,et al. A role for Lin28 in primordial germ cell development and germ cell malignancy , 2009, Nature.
[21] S. Nelson,et al. Expanding the phenotype of mutations in DICER1: mosaic missense mutations in the RNase IIIb domain of DICER1 cause GLOW syndrome , 2014, Journal of Medical Genetics.
[22] Trevor J Pugh,et al. Exome sequencing of pleuropulmonary blastoma reveals frequent biallelic loss of TP53 and two hits in DICER1 resulting in retention of 5p-derived miRNA hairpin loop sequences , 2014, Oncogene.
[23] L. Robison. The Childhood Cancer Survivor Study: a resource for research of long-term outcomes among adult survivors of childhood cancer. , 2005, Minnesota medicine.
[24] W. Foulkes,et al. Extending the phenotypes associated with DICER1 mutations , 2011, Human mutation.
[25] M. Ritchey,et al. Current management of Wilms' tumor in children. , 2009, Journal of pediatric urology.
[26] Monique W M Jaspers,et al. Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. , 2007, JAMA.
[27] R. Sieber. [Kidney tumors in children and therapeutic results]. , 1954, Bruns' Beitrage zur klinischen Chirurgie.
[28] Michael W Pfaffl,et al. RNA integrity and the effect on the real-time qRT-PCR performance. , 2006, Molecular aspects of medicine.
[29] M. Rivera,et al. Wilms' tumour: connecting tumorigenesis and organ development in the kidney , 2005, Nature Reviews Cancer.
[30] P. Grundy,et al. Recurrent somatic mutation in DROSHA induces microRNA profile changes in Wilms tumour , 2014, Nature Communications.
[31] J. Vandesompele,et al. Monoallelic but not biallelic loss of Dicer1 promotes tumorigenesis in vivo , 2010, Cell Death and Differentiation.
[32] Giovanni Parmigiani,et al. Integrated genomic analyses identify ARID1A and ARID1B alterations in the childhood cancer neuroblastoma , 2012, Nature Genetics.
[33] Eric Westhof,et al. Single Processing Center Models for Human Dicer and Bacterial RNase III , 2004, Cell.
[34] W. Foulkes,et al. Germline DICER1 mutation and associated loss of heterozygosity in a pineoblastoma , 2012, Journal of Medical Genetics.
[35] G. Sasso,et al. Late Toxicity in Wilms Tumor Patients Treated With Radiotherapy at 15 Years of Median Follow-up , 2010, Journal of pediatric hematology/oncology.
[36] W. Foulkes,et al. Biallelic DICER1 mutations occur in Wilms tumours , 2013, The Journal of pathology.
[37] S. Miyano,et al. Biallelic DICER1 mutations in sporadic pleuropulmonary blastoma. , 2014, Cancer research.
[38] D. Huntsman,et al. Cancer‐associated somatic DICER1 hotspot mutations cause defective miRNA processing and reverse‐strand expression bias to predominantly mature 3p strands through loss of 5p strand cleavage , 2013, The Journal of pathology.
[39] Grace E. Hallenbeck,et al. DEK promotes HPV positive and negative head and neck cancer cell proliferation , 2014, Oncogene.
[40] C. Perez,et al. Late Effects of Treatment for Wilms’ Tumor , 1984 .
[41] Hao Zhu,et al. Lin28 sustains early renal progenitors and induces Wilms tumor , 2014, Genes & development.
[42] M. Coppes,et al. Management of Wilms' tumour: current practice and future goals. , 2004, The Lancet. Oncology.
[43] V. Kim,et al. The Drosha-DGCR8 complex in primary microRNA processing. , 2004, Genes & development.
[44] V. Kim,et al. The nuclear RNase III Drosha initiates microRNA processing , 2003, Nature.
[45] Gretchen M. Williams,et al. DICER1 Mutations in Familial Pleuropulmonary Blastoma , 2009, Science.
[46] Michael A. Beer,et al. Lin-28B transactivation is necessary for Myc-mediated let-7 repression and proliferation , 2009, Proceedings of the National Academy of Sciences.
[47] Keara M. Lane,et al. Dicer1 functions as a haploinsufficient tumor suppressor. , 2009, Genes & development.
[48] R. Stallings,et al. LIN28B induces neuroblastoma and enhances MYCN levels via let-7 suppression , 2012, Nature Genetics.
[49] M. Gessler,et al. Subtype-Specific FBXW7 Mutation and MYCN Copy Number Gain in Wilms' Tumor , 2010, Clinical Cancer Research.
[50] W. Filipowicz,et al. The widespread regulation of microRNA biogenesis, function and decay , 2010, Nature Reviews Genetics.
[51] David T. W. Jones,et al. Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma , 2012, Nature.
[52] Steven J. M. Jones,et al. Recurrent somatic DICER1 mutations in nonepithelial ovarian cancers. , 2012, The New England journal of medicine.
[53] T. Jacks,et al. Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras. , 2001, Genes & development.
[54] Angela N. Brooks,et al. Structural Basis for Double-Stranded RNA Processing by Dicer , 2006, Science.