Biomedical Applications of Polymeric Nanofibers

Multiscale Fibrous Scaffolds in Regenerative Medicine, by Sowmya Srinivasan, R. Jayakumar, K. P. Chennazhi, Erica J. Levorson, Antonios G. Mikos and Shantikumar V. Nair.- Stem Cells and Nanostructures for Advanced Tissue Regeneration, by Molamma P. Prabhakaran, J. Venugopal, Laleh Ghasemi-Mobarakeh, Dan Kai Guorui Jin and Seeram Ramakrishna.- Creating Electrospun Nanofiber-Based Biomimetic Scaffolds for Bone Regeneration, by Eleni Katsanevakis, Xuejun Wen and Ning Zhang.- Synthetic/Biopolymer Nanofibrous Composites as Dynamic Tissue Engineering Scaffolds, by J. A. Kluge and R. L. Mauck.- Electrospun Fibers as Substrates for Peripheral Nerve Regeneration, by Jorg Mey, Gary Brook, Dorothee Hodde and Andreas Kriebel.- Highly Aligned Polymer Nanofiber Structures: Fabrication and Applications in Tissue Engineering, by Vince Beachley, Eleni Katsanevakis, Ning Zhang, Xuejun Wen.- Electrospinning of Biocompatible Polymers and Their Potentials in Biomedical Applications, by Pitt Supaphol, Orawan Suwantong, Pakakrong Sangsanoh, Sowmya Srinivasan, Rangasamy Jayakumar and Shantikumar V. Nair.- Electrospun Nanofibrous Scaffolds-Current Status and Prospects in Drug Delivery, by M. Prabaharan, R. Jayakumar and S. V. Nair.- Biomedical Applications of Polymer/Silver Composite Nanofibers, by R. Jayakumar, M. Prabaharan, K. T. Shalumon, K. P. Chennazhi and S. V. Nair.

[1]  David L. Kaplan,et al.  Role of pH and charge on silk protein assembly in insects and spiders , 2006 .

[2]  S. Ramakrishna,et al.  In vitro study of smooth muscle cells on polycaprolactone and collagen nanofibrous matrices , 2005, Cell biology international.

[3]  David L Kaplan,et al.  Spider silks and their applications. , 2008, Trends in biotechnology.

[4]  Zheng-ming Huang,et al.  Development of braided drug-loaded nanofiber sutures , 2010, Nanotechnology.

[5]  Nandan L Nerurkar,et al.  Mechanics of oriented electrospun nanofibrous scaffolds for annulus fibrosus tissue engineering , 2007, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[6]  N. Manolova,et al.  Electrospun nano-fibre mats with antibacterial properties from quaternised chitosan and poly(vinyl alcohol). , 2006, Carbohydrate research.

[7]  D. Maniglio,et al.  Biohybrid nanofiber constructs with anisotropic biomechanical properties. , 2011, Journal of biomedical materials research. Part B, Applied biomaterials.

[8]  Ross A. Marklein,et al.  The potential to improve cell infiltration in composite fiber-aligned electrospun scaffolds by the selective removal of sacrificial fibers. , 2008, Biomaterials.

[9]  David L Kaplan,et al.  In vitro degradation of silk fibroin. , 2005, Biomaterials.

[10]  Kwangsok Kim,et al.  Structure and process relationship of electrospun bioabsorbable nanofiber membranes , 2002 .

[11]  Aihua He,et al.  Gelatin and gelatin-hyaluronic acid nanofibrous membranes produced by electrospinning of their aqueous solutions. , 2006, Biomacromolecules.

[12]  B. Ding,et al.  Preparation and characterization of a nanoscale poly(vinyl alcohol) fiber aggregate produced by an electrospinning method , 2002 .

[13]  Seeram Ramakrishna,et al.  Electrospun nanofiber fabrication as synthetic extracellular matrix and its potential for vascular tissue engineering. , 2004, Tissue engineering.

[14]  Kimberly A Woodhouse,et al.  Culture on electrospun polyurethane scaffolds decreases atrial natriuretic peptide expression by cardiomyocytes in vitro. , 2008, Biomaterials.

[15]  G. Wnek,et al.  Electrospinning of collagen nanofiber scaffolds from benign solvents. , 2009, Macromolecular rapid communications.

[16]  D. Kaplan,et al.  Production of Submicron Diameter Silk Fibers under Benign Processing Conditions by Two-Fluid Electrospinning , 2006 .

[17]  D. Kaplan,et al.  Electrospun silk biomaterial scaffolds for regenerative medicine. , 2009, Advanced drug delivery reviews.

[18]  David L Kaplan,et al.  Human bone marrow stromal cell responses on electrospun silk fibroin mats. , 2004, Biomaterials.

[19]  Xiaoyan Yuan,et al.  A nanofibrous composite membrane of PLGA-chitosan/PVA prepared by electrospinning , 2006 .

[20]  Pankaj Gupta,et al.  Some investigations on the fiber formation by utilizing a side-by-side bicomponent electrospinning approach , 2003 .

[21]  S. Hudson,et al.  Chitosan-coated poly(vinyl alcohol) nanofibers for wound dressings. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[22]  K. Woodhouse,et al.  Development of Biodegradable Polyurethane Scaffolds Using Amino Acid and Dipeptide-Based Chain Extenders for Soft Tissue Engineering , 2010, Journal of biomaterials science. Polymer edition.

[23]  Xiaoyan Yuan,et al.  Hybrid nanofibrous membranes of PLGA/chitosan fabricated via an electrospinning array. , 2007, Journal of biomedical materials research. Part A.

[24]  L. Ye,et al.  Electrospinning and biocompatibility evaluation of biodegradable polyurethanes based on L-lysine diisocyanate and L-lysine chain extender. , 2011, Journal of biomedical materials research. Part A.

[25]  Yuan Ji,et al.  Dual-syringe reactive electrospinning of cross-linked hyaluronic acid hydrogel nanofibers for tissue engineering applications. , 2006, Macromolecular bioscience.

[26]  Jun-Jian Liu,et al.  Peripheral nerve regeneration using composite poly(lactic acid-caprolactone)/nerve growth factor conduits prepared by coaxial electrospinning. , 2011, Journal of biomedical materials research. Part A.

[27]  T. Albert,et al.  Donor Site Morbidity After Anterior Iliac Crest Bone Harvest for Single-Level Anterior Cervical Discectomy and Fusion , 2003, Spine.

[28]  Casey K Chan,et al.  The fabrication of nano-hydroxyapatite on PLGA and PLGA/collagen nanofibrous composite scaffolds and their effects in osteoblastic behavior for bone tissue engineering. , 2009, Bone.

[29]  Myung-Seob Khil,et al.  Electrospun nanofibrous polyurethane membrane as wound dressing. , 2003, Journal of biomedical materials research. Part B, Applied biomaterials.

[30]  J. Feijen,et al.  Mechanical properties of single electrospun collagen type I fibers. , 2008, Biomaterials.

[31]  David L Kaplan,et al.  Electrospun silk-BMP-2 scaffolds for bone tissue engineering. , 2006, Biomaterials.

[32]  R. Schoental Carcinogenic and Chronic Effects of 4,4′-Diaminodiphenylmethane, an Epoxyresin Hardener , 1968, Nature.

[33]  R. Gorga,et al.  Nanofibrous composites for tissue engineering applications. , 2009, Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology.

[34]  Mohammad K. Hassan,et al.  Biodegradable aliphatic thermoplastic polyurethane based on poly(ε‐caprolactone) and L‐lysine diisocyanate , 2006 .

[35]  Burak Erman,et al.  Electrospinning of polyurethane fibers , 2002 .

[36]  Jason A Burdick,et al.  Hydrolytically degradable hyaluronic acid hydrogels with controlled temporal structures. , 2008, Biomacromolecules.

[37]  Kwangsok Kim,et al.  Control of degradation rate and hydrophilicity in electrospun non-woven poly(D,L-lactide) nanofiber scaffolds for biomedical applications. , 2003, Biomaterials.

[38]  Andreas Greiner,et al.  Poly(vinyl alcohol) nanofibers by electrospinning as a protein delivery system and the retardation of enzyme release by additional polymer coatings. , 2005, Biomacromolecules.

[39]  R. Reis,et al.  Solving cell infiltration limitations of electrospun nanofiber meshes for tissue engineering applications. , 2010, Nanomedicine.

[40]  Darren M Brey,et al.  Electrospinning of photocrosslinked and degradable fibrous scaffolds. , 2008, Journal of biomedical materials research. Part A.

[41]  Hyoun‐Ee Kim,et al.  Production of electrospun gelatin nanofiber by water-based co-solvent approach , 2008, Journal of materials science. Materials in medicine.

[42]  G. Wnek,et al.  Regulation of cellular infiltration into tissue engineering scaffolds composed of submicron diameter fibrils produced by electrospinning. , 2005, Acta biomaterialia.

[43]  William R Wagner,et al.  Fabrication of biodegradable elastomeric scaffolds with sub-micron morphologies. , 2004, Journal of biomedical materials research. Part A.

[44]  Yi-Dong Lin,et al.  Biodegradable Core/Shell Fibers by Coaxial Electrospinning: Processing, Fiber Characterization, and Its Application in Sustained Drug Release , 2010 .

[45]  P. Baumgarten,et al.  Electrostatic spinning of acrylic microfibers , 1971 .

[46]  C. Yao,et al.  Fabrication of zein/hyaluronic acid fibrous membranes by electrospinning , 2007, Journal of biomaterials science. Polymer edition.

[47]  Benjamin Chu,et al.  Structure and morphology changes during in vitro degradation of electrospun poly(glycolide-co-lactide) nanofiber membrane. , 2003, Biomacromolecules.

[48]  G. Bowlin,et al.  Preliminary Investigation of Airgap Electrospun Silk-Fibroin-Based Structures for Ligament Analogue Engineering , 2011, Journal of biomaterials science. Polymer edition.

[49]  Hau-Min Liou,et al.  Electrospun hyaluronate-collagen nanofibrous matrix and the effects of varying the concentration of hyaluronate on the characteristics of foreskin fibroblast cells. , 2010, Acta biomaterialia.

[50]  D. Bruns,et al.  Oxidation of polyethylene glycols by alcohol dehydrogenase. , 1989, Biochemical pharmacology.

[51]  A. Weiss,et al.  Elastin as a nonthrombogenic biomaterial. , 2011, Tissue engineering. Part B, Reviews.

[52]  Brendon M. Baker,et al.  Tissue engineering with meniscus cells derived from surgical debris. , 2009, Osteoarthritis and cartilage.

[53]  David G Simpson,et al.  Electrospinning of collagen nanofibers. , 2002, Biomacromolecules.

[54]  Karthik Nagapudi,et al.  Engineered collagen–PEO nanofibers and fabrics , 2001, Journal of biomaterials science. Polymer edition.

[55]  S. Ramakrishna,et al.  Double‐layered composite nanofibers and their mechanical performance , 2005 .

[56]  G. L. Woo,et al.  Synthesis and characterization of a novel biodegradable antimicrobial polymer. , 2000, Biomaterials.

[57]  Frank Ko,et al.  Electrostatic fabrication of ultrafine conducting fibers: polyaniline/polyethylene oxide blends , 2000 .

[58]  Akio Okamoto,et al.  Electro-spinning and electro-blowing of hyaluronic acid. , 2004, Biomacromolecules.

[59]  Jintu Fan,et al.  Electrospinning of small diameter 3-D nanofibrous tubular scaffolds with controllable nanofiber orientations for vascular grafts , 2010, Journal of materials science. Materials in medicine.

[60]  Benjamin Chu,et al.  Functional electrospun nanofibrous scaffolds for biomedical applications. , 2007, Advanced drug delivery reviews.

[61]  Yu-Zhong Wang,et al.  Fabrication and characterization of hydrophilic electrospun membranes made from the block copolymer of poly(ethylene glycol-co-lactide). , 2007, Journal of biomedical materials research. Part A.

[62]  E. Chaikof,et al.  High-resolution analysis of engineered type I collagen nanofibers by electron microscopy. , 2001, Scanning.

[63]  Tetsuo Asakura,et al.  Preparation of non-woven nanofibers of Bombyx mori silk, Samia cynthia ricini silk and recombinant hybrid silk with electrospinning method , 2003 .

[64]  S. Ramakrishna,et al.  Characterization of the surface biocompatibility of the electrospun PCL-collagen nanofibers using fibroblasts. , 2005, Biomacromolecules.

[65]  M. Raghunath,et al.  Electro-spinning of pure collagen nano-fibres - just an expensive way to make gelatin? , 2008, Biomaterials.

[66]  Brian J Sennett,et al.  An anisotropic nanofiber/microsphere composite with controlled release of biomolecules for fibrous tissue engineering. , 2010, Biomaterials.

[67]  Seeram Ramakrishna,et al.  Electrospinning of gelatin fibers and gelatin/PCL composite fibrous scaffolds. , 2005, Journal of biomedical materials research. Part B, Applied biomaterials.

[68]  P. Hu,et al.  Electrospinning of sodium alginate with poly(ethylene oxide) , 2006 .

[69]  Eugene Khor,et al.  Flexible chitin films as potential wound-dressing materials: wound model studies. , 2003, Journal of biomedical materials research. Part A.

[70]  Jason A. Burdick,et al.  Hyaluronic Acid Hydrogels for Biomedical Applications , 2011, Advanced materials.

[71]  Younan Xia,et al.  Coating electrospun poly(epsilon-caprolactone) fibers with gelatin and calcium phosphate and their use as biomimetic scaffolds for bone tissue engineering. , 2008, Langmuir : the ACS journal of surfaces and colloids.

[72]  J. Vacanti,et al.  Synthetic Polymers Seeded with Chondrocytes Provide a Template for New Cartilage Formation , 1991, Plastic and reconstructive surgery.

[73]  M. Kotaki,et al.  A review on polymer nanofibers by electrospinning and their applications in nanocomposites , 2003 .

[74]  Chu Zhang,et al.  Evaluation of cross-linking methods for electrospun gelatin on cell growth and viability. , 2009, Biomacromolecules.

[75]  Jessica D. Schiffman,et al.  Cross-linking chitosan nanofibers. , 2007, Biomacromolecules.

[76]  Jason A Burdick,et al.  Engineering on the straight and narrow: the mechanics of nanofibrous assemblies for fiber-reinforced tissue regeneration. , 2009, Tissue engineering. Part B, Reviews.

[77]  H. Kagan,et al.  Lysyl oxidase: preparation and role in elastin biosynthesis. , 1982, Methods in enzymology.

[78]  Alyssa Panitch,et al.  Polymeric biomaterials for tissue and organ regeneration , 2001 .

[79]  Brendon M. Baker,et al.  New directions in nanofibrous scaffolds for soft tissue engineering and regeneration , 2009, Expert review of medical devices.

[80]  Yan Li,et al.  A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents. , 2005, Journal of controlled release : official journal of the Controlled Release Society.

[81]  Glenn D Prestwich,et al.  Electrospun three-dimensional hyaluronic acid nanofibrous scaffolds. , 2006, Biomaterials.

[82]  Buddy D. Ratner,et al.  Biomaterials Science: An Introduction to Materials in Medicine , 1996 .

[83]  C. Boote,et al.  The organization of collagen in the corneal stroma. , 2004, Experimental eye research.

[84]  G. Simon,et al.  Water absorption and states of water in semicrystalline poly(vinyl alcohol) films , 1996 .

[85]  Hongliang Jiang,et al.  Preparation and characterization of ibuprofen-loaded poly(lactide-co-glycolide)/poly(ethylene glycol)-g-chitosan electrospun membranes , 2004, Journal of biomaterials science. Polymer edition.

[86]  M. Dunn,et al.  Functional evaluation of collagen fiber scaffolds for ACL reconstruction: cyclic loading in proteolytic enzyme solutions. , 2004, Journal of biomedical materials research. Part A.

[87]  P. Supaphol,et al.  Stability improvement of electrospun chitosan nanofibrous membranes in neutral or weak basic aqueous solutions. , 2006, Biomacromolecules.

[88]  K. Woodhouse,et al.  Understanding the biodegradation of polyurethanes: from classical implants to tissue engineering materials. , 2005, Biomaterials.

[89]  Seeram Ramakrishna,et al.  A dynamic liquid support system for continuous electrospun yarn fabrication , 2007 .

[90]  J. Burdick,et al.  Biodegradable fibrous scaffolds with diverse properties by electrospinning candidates from a combinatorial macromer library. , 2010, Acta biomaterialia.

[91]  Kristi L Kiick,et al.  Functionalizing electrospun fibers with biologically relevant macromolecules. , 2005, Biomacromolecules.

[92]  David G Simpson,et al.  Nanofiber technology: designing the next generation of tissue engineering scaffolds. , 2007, Advanced drug delivery reviews.

[93]  David G Simpson,et al.  Utilizing acid pretreatment and electrospinning to improve biocompatibility of poly(glycolic acid) for tissue engineering. , 2004, Journal of biomedical materials research. Part B, Applied biomaterials.

[94]  Cato T Laurencin,et al.  Electrospun nanofibrous structure: a novel scaffold for tissue engineering. , 2002, Journal of biomedical materials research.

[95]  G. Rutledge,et al.  Production of Submicrometer Diameter Fibers by Two‐Fluid Electrospinning , 2004 .

[96]  Darrell H. Reneker,et al.  Beaded nanofibers formed during electrospinning , 1999 .

[97]  Won Ho Park,et al.  Regenerated silk fibroin nanofibers: water vapor-induced structural changes and their effects on the behavior of normal human cells. , 2006, Macromolecular bioscience.

[98]  Hui-li Shao,et al.  Morphology and structure of electrospun mats from regenerated silk fibroin aqueous solutions with adjusting pH. , 2007, International journal of biological macromolecules.

[99]  David L Kaplan,et al.  Electrospinning Bombyx mori silk with poly(ethylene oxide). , 2002, Biomacromolecules.

[100]  Gary E. Wnek,et al.  TAILORING TISSUE ENGINEERING SCAFFOLDS USING ELECTROSTATIC PROCESSING TECHNIQUES: A STUDY OF POLY(GLYCOLIC ACID) ELECTROSPINNING , 2001 .

[101]  M. Morshed,et al.  Study of electrospinning of sodium alginate, blended solutions of sodium alginate/poly(vinyl alcohol) and sodium alginate/poly(ethylene oxide) , 2007 .

[102]  David L Kaplan,et al.  Silk-based biomaterials. , 2003, Biomaterials.

[103]  W. Park,et al.  Time-resolved structural investigation of regenerated silk fibroin nanofibers treated with solvent vapor. , 2006, International journal of biological macromolecules.

[104]  X Y Wang,et al.  Biofunctionalized electrospun silk mats as a topical bioactive dressing for accelerated wound healing. , 2009, Acta biomaterialia.

[105]  Shiao-Wen Tsai,et al.  Growth of Mesenchymal Stem Cells on Electrospun Type I Collagen Nanofibers , 2006, Stem cells.

[106]  Darrell H. Reneker,et al.  Electrospinning process and applications of electrospun fibers , 1993, Conference Record of the 1993 IEEE Industry Applications Conference Twenty-Eighth IAS Annual Meeting.

[107]  Y. Ikada,et al.  Electrospun chitosan-P(LLA-CL) nanofibers for biomimetic extracellular matrix , 2008, Journal of biomaterials science. Polymer edition.

[108]  Anthony Atala,et al.  In vitro evaluation of electrospun nanofiber scaffolds for vascular graft application. , 2007, Journal of biomedical materials research. Part A.

[109]  K. Woodhouse,et al.  Characterization of biodegradable polyurethane microfibers for tissue engineering , 2007, Journal of biomaterials science. Polymer edition.

[110]  Darrell H. Reneker,et al.  Bending instability of electrically charged liquid jets of polymer solutions in electrospinning , 2000 .

[111]  Seeram Ramakrishna,et al.  Preparation of Core−Shell Structured PCL-r-Gelatin Bi-Component Nanofibers by Coaxial Electrospinning , 2004 .

[112]  Yi Hong,et al.  Generating elastic, biodegradable polyurethane/poly(lactide-co-glycolide) fibrous sheets with controlled antibiotic release via two-stream electrospinning. , 2008, Biomacromolecules.

[113]  Andreas Greiner,et al.  Compound Core–Shell Polymer Nanofibers by Co‐Electrospinning , 2003 .

[114]  Miqin Zhang,et al.  Alginate‐Based Nanofibrous Scaffolds: Structural, Mechanical, and Biological Properties , 2006 .

[115]  David L Kaplan,et al.  In vitro evaluation of electrospun silk fibroin scaffolds for vascular cell growth. , 2008, Biomaterials.

[116]  S. Boyce,et al.  Engineered human skin fabricated using electrospun collagen-PCL blends: morphogenesis and mechanical properties. , 2009, Tissue engineering. Part A.

[117]  Sachiko Sukigara,et al.  Regeneration of Bombyx mori silk by electrospinning—part 1: processing parameters and geometric properties , 2003 .

[118]  David G Simpson,et al.  Electrospinning collagen and elastin: preliminary vascular tissue engineering. , 2004, Frontiers in bioscience : a journal and virtual library.

[119]  Holger Schönherr,et al.  Chain Packing in Electro-Spun Poly(ethylene oxide) Visualized by Atomic Force Microscopy , 1996 .

[120]  Young-Mi Kang,et al.  Nanofiber alignment and direction of mechanical strain affect the ECM production of human ACL fibroblast. , 2005, Biomaterials.

[121]  D. Fang,et al.  Electrospinning of Hyaluronic acid (HA) and HA/Gelatin Blends , 2006 .

[122]  William R. Wagner,et al.  Hybrid nanofibrous scaffolds from electrospinning of a synthetic biodegradable elastomer and urinary bladder matrix , 2008, Journal of biomaterials science. Polymer edition.

[123]  Xiaoyan Yuan,et al.  Preparation of electrospun chitosan/poly(vinyl alcohol) membranes , 2007 .

[124]  Viola Vogel,et al.  Optimization strategies for electrospun silk fibroin tissue engineering scaffolds. , 2009, Biomaterials.

[125]  Kousaku Ohkawa,et al.  Electrospinning of Chitosan , 2004 .

[126]  J. Vacanti,et al.  A biodegradable nanofiber scaffold by electrospinning and its potential for bone tissue engineering. , 2003, Biomaterials.

[127]  G. Prestwich,et al.  Rheological properties of cross-linked hyaluronan-gelatin hydrogels for tissue engineering. , 2009, Macromolecular bioscience.

[128]  C. Schauer,et al.  Crosslinked, electrospun chitosan–poly(ethylene oxide) nanofiber mats , 2008 .

[129]  R Langer,et al.  Neocartilage formation in vitro and in vivo using cells cultured on synthetic biodegradable polymers. , 1993, Journal of biomedical materials research.

[130]  Su Yan,et al.  Poly(l-lactide-co-ɛ-caprolactone) electrospun nanofibers for encapsulating and sustained releasing proteins , 2009 .

[131]  Xiaoyan Yuan,et al.  Degradation of electrospun PLGA-chitosan/PVA membranes and their cytocompatibility in vitro , 2007, Journal of biomaterials science. Polymer edition.

[132]  K. Woodhouse,et al.  Synthesis and characterization of degradable polyurethane elastomers containing and amino acid-based chain extender. , 1998, Journal of biomaterials science. Polymer edition.

[133]  Fang Xie,et al.  Effect of shearing on formation of silk fibers from regenerated Bombyx mori silk fibroin aqueous solution. , 2006, International journal of biological macromolecules.

[134]  Y Ikada,et al.  In vitro and in vivo degradation of films of chitin and its deacetylated derivatives. , 1997, Biomaterials.

[135]  Brendon M. Baker,et al.  Fabrication and modeling of dynamic multipolymer nanofibrous scaffolds. , 2009, Journal of biomechanical engineering.

[136]  Sachiko Sukigara,et al.  Regeneration of Bombyx mori silk by electrospinning. Part 2. Process optimization and empirical modeling using response surface methodology , 2004 .

[137]  J. A. Cooper,et al.  Fabrication and characterization of six electrospun poly(alpha-hydroxy ester)-based fibrous scaffolds for tissue engineering applications. , 2006, Acta biomaterialia.

[138]  W. Park,et al.  Blood compatibility and biodegradability of partially N-acylated chitosan derivatives. , 1995, Biomaterials.

[139]  John Layman,et al.  Release of tetracycline hydrochloride from electrospun poly(ethylene-co-vinylacetate), poly(lactic acid), and a blend. , 2002, Journal of controlled release : official journal of the Controlled Release Society.

[140]  Il Keun Kwon,et al.  Co-electrospun nanofiber fabrics of poly(L-lactide-co-epsilon-caprolactone) with type I collagen or heparin. , 2005, Biomacromolecules.

[141]  Jacqueline T Johanas,et al.  Dynamic culture conditions to generate silk-based tissue-engineered vascular grafts. , 2009, Biomaterials.

[142]  Seung Jin Lee,et al.  Electrospinning of polysaccharides for regenerative medicine. , 2009, Advanced drug delivery reviews.

[143]  Huarong Nie,et al.  Effects of chain conformation and entanglement on the electrospinning of pure alginate. , 2008, Biomacromolecules.

[144]  David L Kaplan,et al.  Regulation of silk material structure by temperature-controlled water vapor annealing. , 2011, Biomacromolecules.

[145]  Xiaoyan Yuan,et al.  Electrospinning of chitosan solutions in acetic acid with poly(ethylene oxide) , 2004, Journal of biomaterials science. Polymer edition.

[146]  K. Woodhouse,et al.  Structure‐property relationships of degradable polyurethane elastomers containing an amino acid‐based chain extender , 2000 .

[147]  Computational Methods for the Development of Polymeric Biomaterials , 2010 .

[148]  Myung-Seob Khil,et al.  Characterization of nano-structured poly(ε-caprolactone) nonwoven mats via electrospinning , 2003 .

[149]  R. Tuan,et al.  Biological response of chondrocytes cultured in three-dimensional nanofibrous poly(epsilon-caprolactone) scaffolds. , 2003, Journal of biomedical materials research. Part A.

[150]  J. Burdick,et al.  Electrospun fibrous scaffolds with multiscale and photopatterned porosity. , 2010, Macromolecular bioscience.

[151]  Won Ho Park,et al.  Electrospinning of chitin nanofibers: degradation behavior and cellular response to normal human keratinocytes and fibroblasts. , 2006, Biomaterials.

[152]  David L. Kaplan,et al.  Mechanism of silk processing in insects and spiders , 2003, Nature.

[153]  G. Bowlin,et al.  Electrospinning of collagen/biopolymers for regenerative medicine and cardiovascular tissue engineering. , 2009, Advanced drug delivery reviews.

[154]  Sachiko Sukigara,et al.  Regeneration of Bombyx mori silk by electrospinning. Part 3: characterization of electrospun nonwoven mat , 2005 .

[155]  D. C. Knapp,et al.  Electrospun polydioxanone–elastin blends: potential for bioresorbable vascular grafts , 2006, Biomedical materials.

[156]  Dietmar Werner Hutmacher,et al.  Composite electrospun scaffolds for engineering tubular bone grafts. , 2009, Tissue engineering. Part A.

[157]  Xue-chao Hu,et al.  Structure of silk fibroin fibers made by an electrospinning process from a silk fibroin aqueous solution , 2006 .

[158]  Eugene Khor,et al.  Flexible chitin films: structural studies. , 2004, Carbohydrate research.

[159]  Younan Xia,et al.  Direct Fabrication of Composite and Ceramic Hollow Nanofibers by Electrospinning , 2004 .

[160]  Michael S Sacks,et al.  Synthesis, characterization, and cytocompatibility of elastomeric, biodegradable poly(ester-urethane)ureas based on poly(caprolactone) and putrescine. , 2002, Journal of biomedical materials research.

[161]  Xuesi Chen,et al.  Co-electrospun poly(lactide-co-glycolide), gelatin, and elastin blends for tissue engineering scaffolds. , 2006, Journal of biomedical materials research. Part A.

[162]  J. A. Cooper,et al.  Engineering controllable anisotropy in electrospun biodegradable nanofibrous scaffolds for musculoskeletal tissue engineering. , 2007, Journal of biomechanics.

[163]  Eyal Zussman,et al.  Encapsulation of Enzymes in Biodegradable Tubular Structures , 2008 .

[164]  D. C. Knapp,et al.  Thermal and Mechanical Characterization of Electrospun Blends of Poly(lactic acid) and Poly(glycolic acid) , 2006 .

[165]  M. Sacks,et al.  Biodegradable poly(ether ester urethane)urea elastomers based on poly(ether ester) triblock copolymers and putrescine: synthesis, characterization and cytocompatibility. , 2004, Biomaterials.

[166]  Tomokazu Sato,et al.  Fabrication of blend biodegradable nanofibrous nonwoven mats via multi-jet electrospinning , 2004 .

[167]  H. Mankin,et al.  Infection in Massive Bone Allografts , 2005, Clinical orthopaedics and related research.

[168]  Anthony S Weiss,et al.  Electrospun protein fibers as matrices for tissue engineering. , 2005, Biomaterials.

[169]  X. Wen,et al.  Fabrication of Nanofiber Reinforced Protein Structures For Tissue Engineering. , 2009, Materials science & engineering. C, Materials for biological applications.

[170]  A. Subramanian,et al.  Preparation and evaluation of the electrospun chitosan/PEO fibers for potential applications in cartilage tissue engineering , 2005, Journal of biomaterials science. Polymer edition.

[171]  M. Henriksson,et al.  Electrospinning of cellulose‐based nanofibers , 2007 .

[172]  Yan Li,et al.  Modulation of protein release from biodegradable core-shell structured fibers prepared by coaxial electrospinning. , 2006, Journal of biomedical materials research. Part B, Applied biomaterials.

[173]  R. Kandel,et al.  Characterization of a biodegradable electrospun polyurethane nanofiber scaffold: Mechanical properties and cytotoxicity. , 2010, Acta biomaterialia.