Development of New End-Effector for Proof-of-Concept of Fully Robotic Multichannel Biopsy

This paper presents a novel end-effector designed for a teleoperation type robotic system to perform automated sampling for needle biopsies. The objectives of the robotic system are to realize teleoperation control of the pose and position of the biopsy instrument to reduce X-ray exposure and enhance the precision and accuracy of the procedure as well as to automate the sequence of multiple samplings during the biopsy. In order to realize the desired functions, the end-effector comprises three modules: the needle cartridge, needle positioning mechanism, and needle driving unit. The detachable needle cartridge contains six needle sets: one guide needle and five sampling needles. It rotates itself to change needles and rotates the needle body to adjust the facing angle of the needle tip. The needle positioning mechanism is spherical with two degrees of freedom and is a modification of the typical hemisphere type. The needle driving unit controls the needle grab/release and insertion/retreat motions. A concept design and prototype were developed with an experimental master-salve system for the teleoperation. The experimental results successfully demonstrated the feasibility of the robotic biopsy procedure.

[1]  Y. Hiroi,et al.  Are bigger robots scary? —The relationship between robot size and psychological threat— , 2008, 2008 IEEE/ASME International Conference on Advanced Intelligent Mechatronics.

[2]  Dan Stoianovici,et al.  AcuBot: a robot for radiological interventions , 2003, IEEE Trans. Robotics Autom..

[3]  Carl D. Crane,et al.  Reverse kinetostatic analysis and stiffness synthesis of a spatial tensegrity-based compliant mechanism , 2013 .

[4]  K. Tadano,et al.  Achieving Haptic Perception in Forceps’ Manipulator Using Pneumatic Artificial Muscle , 2013, IEEE/ASME Transactions on Mechatronics.

[5]  Bernard Bayle,et al.  Kinematic modeling of a 5-DOF parallel mechanism for semi-spherical workspace , 2009 .

[6]  Gabor Fichtinger,et al.  A workspace‐orientated needle‐guiding robot for 3T MRI‐guided transperineal prostate intervention: evaluation of in‐bore workspace and MRI compatibility , 2013, The international journal of medical robotics + computer assisted surgery : MRCAS.

[7]  Hyo-Jeong Cha,et al.  Implementation of a 4-DOF parallel mechanism as a needle insertion device , 2010, 2010 IEEE International Conference on Robotics and Automation.

[8]  T. Podder,et al.  In vivo motion and force measurement of surgical needle intervention during prostate brachytherapy. , 2006, Medical physics.

[9]  Kemal Tuncali,et al.  Design of an Instrument Guide for MRI-Guided Percutaneous Interventions , 2011 .

[10]  O. Wendt,et al.  Schnittgeschwindigkeiten und Biopsieerfolg unterschiedlicher Stanzbiopsieinstrumente , 2001, Der Radiologe.

[11]  Xiaofei Wang,et al.  Kinematics analysis of the coupled tendon-driven robot based on the product-of-exponentials formula , 2013 .

[12]  José Antonio Cruz-Ledesma,et al.  Modelling, Design and Robust Control of a Remotely Operated Underwater Vehicle , 2014 .

[13]  M. Moallem,et al.  A Novel Manipulator for Percutaneous Needle Insertion: Design and Experimentation , 2009, IEEE/ASME Transactions on Mechatronics.

[14]  Conor J. Walsh,et al.  A Patient-Mounted, Telerobotic Tool for CT-Guided Percutaneous , 2008 .

[15]  Bernard Bayle,et al.  A Force Feedback Teleoperated Needle Insertion Device for Percutaneous Procedures , 2009, Int. J. Robotics Res..

[16]  Madan M Rehani,et al.  Radiation-associated lens opacities in catheterization personnel: results of a survey and direct assessments. , 2013, Journal of vascular and interventional radiology : JVIR.

[17]  Carlo Catalano,et al.  Preliminary clinical experience with a dedicated interventional robotic system for CT-guided biopsies of lung lesions: a comparison with the conventional manual technique , 2015, European Radiology.

[18]  Allison M. Okamura,et al.  Force modeling for needle insertion into soft tissue , 2004, IEEE Transactions on Biomedical Engineering.

[19]  M. Bock,et al.  INNOMOTION for Percutaneous Image-Guided Interventions , 2008, IEEE Engineering in Medicine and Biology Magazine.

[20]  Mark R Prausnitz,et al.  Insertion of microneedles into skin: measurement and prediction of insertion force and needle fracture force. , 2004, Journal of biomechanics.

[21]  Byung-Ju Yi,et al.  An Image-Guided Robotic Surgery System for Spinal Fusion , 2006 .

[22]  M. Cenk Cavusoglu,et al.  Regular Paper Submission for the Ieee Transactions on Mechatronics Design of a Parallel Robot for Needle Based Interventions on Small Animals¨ozkan , 2022 .

[23]  Nikolai Hungr,et al.  Interventional Radiology Robot for CT and MRI Guided Percutaneous Interventions , 2011, MICCAI.

[24]  Gabor Fichtinger,et al.  Virtual Remote Center of Motion control for needle placement robots , 2004 .

[25]  Masakatsu G. Fujie,et al.  Development of an integrated needle insertion system with image guidance and deformation simulation , 2010, Comput. Medical Imaging Graph..

[26]  Sang Min Lee,et al.  Percutaneous transthoracic needle biopsy of small (≤1 cm) lung nodules under C-arm cone-beam CT virtual navigation guidance , 2012, European Radiology.

[27]  Rajnikant V. Patel,et al.  Autonomous Image-Guided Robot-Assisted Active Catheter Insertion , 2008, IEEE Transactions on Robotics.

[28]  Dan Stoianovici,et al.  Does needle rotation improve lesion targeting? , 2011, The international journal of medical robotics + computer assisted surgery : MRCAS.

[29]  Mu-Lien Lin,et al.  A miniature patient‐mount navigation system for assisting needle placement in CT‐guided intervention , 2011, The international journal of medical robotics + computer assisted surgery : MRCAS.

[30]  Lena Maier-Hein,et al.  Development and evaluation of a new image-based user interface for robot-assisted needle placements with the Robopsy system , 2009, Medical Imaging.

[31]  Robert D. Howe,et al.  Robotic catheter cardiac ablation combining ultrasound guidance and force control , 2014, Int. J. Robotics Res..

[32]  K Cleary,et al.  A novel end‐effector design for robotics in image‐guided needle procedures , 2006, The international journal of medical robotics + computer assisted surgery : MRCAS.

[33]  Hiroaki Kobayashi,et al.  Analysis, Classification, and Design of Tendon-Driven Mechanisms , 2014, IEEE Transactions on Robotics.

[34]  Jaesoon Choi,et al.  Design and Kinematic Analysis of a New End-Effector for a Robotic Needle Insertion-Type Intervention System , 2014 .

[35]  Chin-Hsing Kuo,et al.  Kinematic design considerations for minimally invasive surgical robots: an overview , 2012, The international journal of medical robotics + computer assisted surgery : MRCAS.

[36]  Makoto Hashizume,et al.  Development of a needle insertion manipulator for central venous catheterization , 2012, The international journal of medical robotics + computer assisted surgery : MRCAS.

[37]  Jian S. Dai,et al.  Kinematics of a Fully-Decoupled Remote Center-of-Motion Parallel Manipulator for Minimally Invasive Surgery , 2012 .

[38]  Beth A Schueler Operator shielding: how and why. , 2010, Techniques in vascular and interventional radiology.

[39]  Alin Albu-Schäffer,et al.  DLR MiroSurge: a versatile system for research in endoscopic telesurgery , 2010, International Journal of Computer Assisted Radiology and Surgery.

[40]  Jaesoon Choi,et al.  Development of a robotic mechanism for teleoperation-based needle interventions , 2013, IEEE ISR 2013.

[41]  J. Conradie,et al.  Fluoroscopy Based Needle-Positioning System for Percutaneous Nephrolithotomy Procedures , 2008 .

[42]  Alin Albu-Schäffer,et al.  The DLR MiroSurge - A robotic system for surgery , 2009, 2009 IEEE International Conference on Robotics and Automation.

[43]  Bradford J. Wood,et al.  Accuracy and efficacy of percutaneous biopsy and ablation using robotic assistance under computed tomography guidance: a phantom study , 2014, European Radiology.

[44]  Peter Kazanzides,et al.  Robotic assistance for ultrasound-guided prostate brachytherapy , 2008, Medical Image Anal..

[45]  Koji Ikuta,et al.  Pressure Pulse Drive: A Control Method for the Precise Bending of Hydraulic Active Catheters , 2012, IEEE/ASME Transactions on Mechatronics.

[46]  Russell H. Taylor,et al.  A Modular Surgical Robotic System for Image Guided Percutaneous Procedures , 1998, MICCAI.

[47]  Stephan Zangos,et al.  Accuracy and speed of robotic assisted needle interventions using a modern cone beam computed tomography intervention suite: a phantom study , 2012, European Radiology.

[48]  R. Arceci Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing , 2012 .

[49]  Lena Maier-Hein,et al.  Human vs. robot operator error in a needle-based navigation system for percutaneous liver interventions , 2009, Medical Imaging.

[50]  Jacques Gangloff,et al.  CTBot: A stereotactic-guided robotic assistant for percutaneous procedures of the abdomen , 2005, SPIE Medical Imaging.