Role of C3, C5 and anaphylatoxin receptors in acute lung injury and in sepsis.

[1]  Jennifer R. Clark,et al.  A Critical Role for C5L2 in the Pathogenesis of Experimental Allergic Asthma , 2010, The Journal of Immunology.

[2]  John D Lambris,et al.  Molecular Intercommunication between the Complement and Coagulation Systems , 2010, The Journal of Immunology.

[3]  P. Ward The Harmful Role of C5a on Innate Immunity in Sepsis , 2010, Journal of Innate Immunity.

[4]  M. Wills-Karp,et al.  Complement-mediated Regulation Of The IL-17A Axis Is A Central Genetic Determinant Of The Severity Of Experimental Allergic Asthma , 2010, ATS 2010.

[5]  C. Mackay,et al.  The C5a Receptor (C5aR) C5L2 Is a Modulator of C5aR-mediated Signal Transduction* , 2009, The Journal of Biological Chemistry.

[6]  P. Monk,et al.  The human complement fragment receptor, C5L2, is a recycling decoy receptor , 2009, Molecular immunology.

[7]  J. V. Sarma,et al.  Functions of the complement components C3 and C5 during sepsis , 2008, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[8]  C. Mackay,et al.  Functional roles for C5a receptors in sepsis , 2008, Nature Medicine.

[9]  C. Mackay,et al.  Receptors for complement C5a. The importance of C5aR and the enigmatic role of C5L2 , 2008, Immunology and cell biology.

[10]  John D Lambris,et al.  Regulation of Toll-like receptor-mediated inflammatory response by complement in vivo. , 2007, Blood.

[11]  B. Nilsson,et al.  Complement and coagulation: strangers or partners in crime? , 2007, Trends in immunology.

[12]  C. McKerlie,et al.  C5L2 is critical for the biological activities of the anaphylatoxins C5a and C3a , 2007, Nature.

[13]  K. Tracey,et al.  Role of HMGB1 in apoptosis-mediated sepsis lethality. , 2006, The Journal of experimental medicine.

[14]  John D Lambris,et al.  Generation of C5a in the absence of C3: a new complement activation pathway , 2006, Nature Medicine.

[15]  John D Lambris,et al.  A regulatory role for the C5a anaphylatoxin in type 2 immunity in asthma. , 2006, The Journal of clinical investigation.

[16]  P. Ward,et al.  Regulation of lung inflammation in the model of IgG immune-complex injury. , 2006, Annual review of pathology.

[17]  G. Su,et al.  An essential role for complement C5a in the pathogenesis of septic cardiac dysfunction , 2006, The Journal of experimental medicine.

[18]  Pixu Liu,et al.  An Anti-inflammatory Function for the Complement Anaphylatoxin C5a-binding Protein, C5L2* , 2005, Journal of Biological Chemistry.

[19]  P. Monk,et al.  C5L2 Is a Functional Receptor for Acylation-stimulating Protein* , 2005, Journal of Biological Chemistry.

[20]  Y. Belkaid,et al.  C5a negatively regulates toll-like receptor 4-induced immune responses. , 2005, Immunity.

[21]  Kevin J. Tracey,et al.  High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal , 2005, Nature Reviews Immunology.

[22]  John D Lambris,et al.  Complement Component C5a Is Integral to the Febrile Response of Mice to Lipopolysaccharide , 2005, Neuroimmunomodulation.

[23]  J. Krause,et al.  C5L2, a nonsignaling C5A binding protein. , 2003, Biochemistry.

[24]  P. Monk,et al.  The Chemoattractant Receptor-like Protein C5L2 Binds the C3a des-Arg77/Acylation-stimulating Protein* , 2003, The Journal of Biological Chemistry.

[25]  John D Lambris,et al.  Protection of innate immunity by C5aR antagonist in septic mice , 2002, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[26]  J. V. Sarma,et al.  Complement-Induced Impairment of Innate Immunity During Sepsis1 , 2002, The Journal of Immunology.

[27]  L. Toledo-Pereyra,et al.  Ischemia/reperfusion injury. , 2002, The Journal of surgical research.

[28]  N. Riedemann,et al.  The FASEB Journal express article 10.1096/fj.02-0033fje. Published online April 23, 2002. C5a receptor and thymocyte apoptosis in sepsis , 2022 .

[29]  A. Schmaier,et al.  Anti-c5a ameliorates coagulation/fibrinolytic protein changes in a rat model of sepsis. , 2002, The American journal of pathology.

[30]  P. Monk,et al.  The Orphan Receptor C5L2 Has High Affinity Binding Sites for Complement Fragments C5a and C5a des-Arg74 * , 2002, The Journal of Biological Chemistry.

[31]  W. Watford,et al.  Surfactant Protein A Regulates Complement Activation1 , 2001, The Journal of Immunology.

[32]  J. Younger,et al.  Protective effects of anti‐C5a peptide antibodies in experimental sepsis , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[33]  W. Watford,et al.  Complement-mediated host defense in the lung. , 2000, American journal of physiology. Lung cellular and molecular physiology.

[34]  J. Nishihira,et al.  Macrophage migration inhibitory factor (MIF): its essential role in the immune system and cell growth. , 2000, Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research.

[35]  G. Peltz,et al.  Identification of complement factor 5 as a susceptibility locus for experimental allergic asthma , 2000, Nature Immunology.

[36]  A. Agah,et al.  Complement activation following oxidative stress. , 1999, Molecular immunology.

[37]  P. Ward,et al.  Protective effects of C5a blockade in sepsis , 1999, Nature Medicine.

[38]  H. Makita,et al.  Effect of anti-macrophage migration inhibitory factor antibody on lipopolysaccharide-induced pulmonary neutrophil accumulation. , 1998, American journal of respiratory and critical care medicine.

[39]  S. Galli,et al.  Impaired mast cell-dependent natural immunity in complement C3-deficient mice , 1997, Nature.

[40]  J. Pittet,et al.  Biological markers of acute lung injury: prognostic and pathogenetic significance. , 1997, American journal of respiratory and critical care medicine.

[41]  R. Bucala,et al.  Regulatory role for macrophage migration inhibitory factor in acute respiratory distress syndrome , 1997, Nature Medicine.

[42]  J. Ravetch,et al.  Immunoglobulin G–mediated Inflammatory Responses Develop Normally in Complement-deficient Mice , 1996, The Journal of experimental medicine.

[43]  P. Ward,et al.  Rous-Whipple Award Lecture. Role of complement in lung inflammatory injury. , 1996, The American journal of pathology.

[44]  P. Ward,et al.  Requirement and role of C5a in acute lung inflammatory injury in rats. , 1996, The Journal of clinical investigation.

[45]  P. Barton,et al.  Complement component C5 modulates the systemic tumor necrosis factor response in murine endotoxic shock , 1993, Infection and immunity.

[46]  P. Ward,et al.  Requirements for neutrophil products and L-arginine in ischemia-reperfusion injury. , 1993, The American journal of pathology.

[47]  K. Cianflone Acylation-stimulating protein. , 1992, CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne.

[48]  C. Gerard,et al.  The chemotactic receptor for human C5a anaphylatoxin , 1991, Nature.

[49]  D. Remick,et al.  Tumor necrosis factor participates in the pathogenesis of acute immune complex alveolitis in the rat. , 1989, The Journal of clinical investigation.

[50]  P. Ward,et al.  Activation of C5 by cobra venom factor is required in neutrophil-mediated lung injury in the rat. , 1987, The American journal of pathology.

[51]  P. Ward,et al.  Source of iron in neutrophil-mediated killing of endothelial cells. , 1987, Laboratory investigation; a journal of technical methods and pathology.

[52]  P. Ward,et al.  Pulmonary endothelial cell killing by human neutrophils. Possible involvement of hydroxyl radical. , 1985, Laboratory investigation; a journal of technical methods and pathology.

[53]  J. Solomkin,et al.  Complement activation and clearance in acute illness and injury: evidence for C5a as a cell-directed mediator of the adult respiratory distress syndrome in man. , 1985, Surgery.

[54]  P. Ward,et al.  Intravascular activation of complement and acute lung injury. Dependency on neutrophils and toxic oxygen metabolites. , 1982, The Journal of clinical investigation.

[55]  G. Larsen,et al.  The pulmonary response of C5 sufficient and deficient mice to immune complexes. , 1981, The American review of respiratory disease.

[56]  L. J. Weaver,et al.  ASSOCIATION OF COMPLEMENT ACTIVATION AND ELEVATED PLASMA-C5a WITH ADULT RESPIRATORY DISTRESS SYNDROME Pathophysiological Relevance and Possible Prognostic Value , 1980, The Lancet.

[57]  P. Ward,et al.  C5 chemotactic fragments produced by an enzyme in lysosomal granules of neutrophils. , 1970, Journal of immunology.

[58]  Cornish Cb,et al.  MEDICAL TREATMENT OF OSTEOARTHRITIS. , 1965, Lancet.

[59]  J. Ravetch,et al.  Divergent roles for Fc receptors and complement in vivo. , 1998, Annual review of immunology.

[60]  P. Ward,et al.  Lung injury and complement activation: role of neutrophils and xanthine oxidase. , 1991, Free radical biology & medicine.