Cystic Degeneration in Porcine Ovaries - Second Communication: Concentrations of Progesterone, Estradiol-17β, and Testosterone in Cystic Fluid and Plasma; Interpretation of the Results

Contents: The content of progesterone, estradiol-17β, and testosterone of plasma and cystic fluid was determined in 79 sows with ovarian cysts. The average progesterone concentration of sows with dark corpora lutea (CL) was higher than of sows with pale or absent CL (39.4 vs. 8.7 vs. 8.0 ng/ml plasma; p < 0.001; and 7512 vs. 3644 vs. 2723 ng/ml cystic fluid, respectively; p < 0.001). The cystic fluid of animals with oligocystic ovaries (10 cystslanimal) had a significant higher progesterone concentration in comparison to potycystic animals (7200 vs. 3682 ng/ml; p < 0.001). Testosterone and estradwl-17β levels in plasma and in cystic fluid of polycystic animals were significantly higher in comparison to oligocystic animals (Plasma-Testosterone: p < 0.01; Plasma-Estradwl: p < 0.05; Cyst-Testosterone: p < 0.01; Cyst-Estradiol: p < 0.001). In oligocystic ovaries testosterone in cysts exceeded the estradiol-17β levels, whereas in polycystic ovaries the situation was vice versa (p < 0.001). It is suggested that cystic ovarian degeneration in the sow is not exclusively a gradually progressing process, rather then a complex syndrome with three components, were characterized by a separate course of development (oligocystic, polycystic. oligo-polycystic syndrome). Inhalt: Zystische Degeneration von Schweineovarien - Zweite Mitteilung: Progesteron-, Ostradiol-17β und Testosteron-Konzentrationen in der Zystenflussigkeit und im Plasma; Interpretation der Ergebnisse Der Progesteron-, 17β-Ostradiol- und Testosterongehalt wurde bei 79 Sauen mit Ovarzysten im Blutplasma und in der Zystenflussigkeit bestimmt. Der durchschnittliche Progesterongehalt war bei Tieren mit dunklen Corpora lutea (Cl) signifikant (P < 0,001) hoher (39,4 ng/ml Plasma; 7512 nghnl Zystenflussigkeit) als bei Sauen mit blassem Gelbkorper (8,7 ng/ml Plasma, 3644 ng/ml Zystenflussigkeit oder als bei Tieren ohne Gelbkorper (8,0 ng/ml Plasma, 2723 ng/ml Zystenflussigkeit). Die Zystenflussigkeit bei Tieren mit geringer Zystenzahl (n 10) hatte eine signifikant hohere Progesteronkonzentration im Vergleich zu polyzystischen Tieren (7200 vs. 3682 nghnl, p < 0,001). Testosteron- und Ostradiol-17β-Konzentrationen waren im Plasma und in der Zystenflussigkeit bei polyzystischen Tieren signifikant hoher als bei oligozystischen Tieren (Plasma-Testosteron: p < 0,01; Plasma-Ostradiol: p < 0,05; Testosteron in Zysten: p < 0,01; Ostradiol in Zysten: p < 0.001). Die Ergebnisse deuten darauf hin, das zystische Ovardegenerationen bei der Sau nicht nu ein graduell fortschreitendef Prozes ist, sondem eher durch ein komplexes Syndrom mit drei Unterbereichen (oligozystisches, polyzystisches oder oligo-polyzystisches Syndmm) charakterisien ist.

[1]  P. H. Li,et al.  Catecholamine inhibition of luteinizing hormone secretion in isolated pig pituitary cells. , 1989, Biology of reproduction.

[2]  R. Kineman,et al.  Localization of proopiomelanocortin (POMC) immunoreactive neurons in the forebrain of the pig. , 1989, Biology of reproduction.

[3]  E. Katz The luteinized unruptured follicle and other ovulatory dysfunctions. , 1988, Fertility and sterility.

[4]  C. Barb,et al.  Absence of brain opioid peptide modulation of luteinizing hormone secretion in the prepubertal gilt. , 1988, Biology of reproduction.

[5]  B. Shapiro,et al.  Correlation of follicular steroid hormone profiles with ovarian cyclicity in sows. , 1988, Journal of reproduction and fertility.

[6]  B. Tsang,et al.  Differential production of steroids by dispersed granulosa and theca interna cells from developing preovulatory follicles of pigs. , 1985, Journal of reproduction and fertility.

[7]  R. Liptrap,et al.  Relationship of Prostaglandin F 2α to Cystic Ovarian Follicles in the Sow , 1981 .

[8]  B. Tsang,et al.  Interrelationships between follicular fluid steroid levels, gonadotropic stimuli, and oocyte maturation during preovulatory development of porcine follicles. , 1980, Biology of reproduction.

[9]  N. Parvizi,et al.  Partial recovery of the stimulatory oestrogen feedback action on LH release during late lactation in the pig. , 1980, Journal of reproduction and fertility.

[10]  F. Elsaesser Effects of active immunization against oestradiol-17 beta, testosterone or progesterone on receptivity in the female rabbit and evaluation of specificity. , 1980, Journal of reproduction and fertility.

[11]  N. Parvizi,et al.  Estrogen feedback in the pig: sexual differentiation and the effect of prenatal testosterone treatment. , 1979, Biology of reproduction.

[12]  E Papiernik,et al.  Healthy and atretic human follicles in the preovulatory phase: differences in evolution of follicular morphology and steroid content of follicular fluid. , 1979, The Journal of clinical endocrinology and metabolism.

[13]  N. Parvizi,et al.  Steroid feedback on luteinizing hormone secretion during sexual maturation in the pig. , 1978, The Journal of endocrinology.

[14]  D. G. Cran,et al.  Macroscopic identification and steroidogenic function of atretic follicles in sheep. , 1978, The Journal of endocrinology.

[15]  D. Smidt,et al.  Plasma luteinizing hormone and progesterone in the adult female pig during the oestrous cycles, late pregnancy and lactation, and after ovariectomy and pentobarbitone treatment. , 1976, The Journal of endocrinology.

[16]  D. Smidt,et al.  Plasma luteinizing hormone and testosterone in the adult male pig: 24 hour fluctuations and the effect of copulation. , 1975, The Journal of endocrinology.

[17]  R. Liptrap,et al.  Plasma progesterone levels in sows with induced cystic ovarian follicles. , 1975, Research in veterinary science.

[18]  R. Liptrap Oestrogen excretion by sows with induced cystic ovarian follicles. , 1973, Research in veterinary science.

[19]  R. Liptrap Effect of corticotrophin and corticosteroids on oestrus, ovulation and oestrogen excretion in the sow. , 1970, The Journal of endocrinology.

[20]  A. Nalbandov Anatomic and endocrine causes of sterility in female swine. , 1952, Fertility and sterility.