Anatoxin‐a, Homoanatoxin‐a, and Natural Analogues

[1]  A. Méjean,et al.  Biosynthesis of anatoxin-a and analogues (anatoxins) in cyanobacteria. , 2014, Toxicon : official journal of the International Society on Toxinology.

[2]  A. Furey,et al.  Ion suppression; a critical review on causes, evaluation, prevention and applications. , 2013, Talanta.

[3]  B. Pawlik-Skowrońska,et al.  Cyanotoxin diversity and food web bioaccumulation in a reservoir with decreasing phosphorus concentrations and perennial cyanobacterial blooms , 2013 .

[4]  B. Neilan,et al.  Neurotoxic Alkaloids from Cyanobacteria , 2013 .

[5]  Matt Nolan,et al.  Improving the coverage of the cyanobacterial phylum using diversity-driven genome sequencing , 2012, Proceedings of the National Academy of Sciences.

[6]  V. Pichon,et al.  Synthesis, configuration assignment, and simultaneous quantification by liquid chromatography coupled to tandem mass spectrometry, of dihydroanatoxin-a and dihydrohomoanatoxin-a together with the parent toxins, in axenic cyanobacterial strains and in environmental samples. , 2012, Toxicon : official journal of the International Society on Toxinology.

[7]  B. Pawlik-Skowrońska,et al.  Simultaneous accumulation of anatoxin-a and microcystins in three fish species indigenous to lakes affected by cyanobacterial blooms , 2012 .

[8]  J. Martínez,et al.  Natural Antibiotic Resistance and Contamination by Antibiotic Resistance Determinants: The Two Ages in the Evolution of Resistance to Antimicrobials , 2012, Front. Microbio..

[9]  V. Vasconcelos,et al.  Development and Validation of an SPE-HPLC-FL Method for the Determination of Anatoxin-a in Water and Trout (Oncorhincus mykiss) , 2011 .

[10]  J. Molgó,et al.  Neurotoxic cyanobacterial toxins. , 2010, Toxicon : official journal of the International Society on Toxinology.

[11]  N. Thomaidis,et al.  Development of a fast and selective method for the sensitive determination of anatoxin-a in lake waters using liquid chromatography–tandem mass spectrometry and phenylalanine-d5 as internal standard , 2010, Analytical and bioanalytical chemistry.

[12]  Bérangère Lombard,et al.  In vitro reconstitution of the first steps of anatoxin-a biosynthesis in Oscillatoria PCC 6506: from free L-proline to acyl carrier protein bound dehydroproline. , 2010, Biochemistry.

[13]  P. Renard,et al.  Synthesis of a (+)-anatoxin-a analogue for monoclonal antibodies production , 2009 .

[14]  V. Vasconcelos,et al.  Production of anatoxin-a by cyanobacterial strains isolated from Portuguese fresh water systems , 2009, Ecotoxicology.

[15]  O. Lequin,et al.  Evidence that biosynthesis of the neurotoxic alkaloids anatoxin-a and homoanatoxin-a in the cyanobacterium Oscillatoria PCC 6506 occurs on a modular polyketide synthase initiated by L-proline. , 2009, Journal of the American Chemical Society.

[16]  K. James,et al.  Chemistry of Cyanobacterial Neurotoxins ‒ Anatoxin‐a: Synthetic Approaches , 2007 .

[17]  K. James,et al.  Anatoxin-a and Analogues: Discovery, Distribution, and Toxicology , 2007 .

[18]  Vitor Vasconcelos,et al.  Toxicology and detection methods of the alkaloid neurotoxin produced by cyanobacteria, anatoxin-a. , 2007, Environment international.

[19]  A. Méjean,et al.  Different Genotypes of Anatoxin-Producing Cyanobacteria Coexist in the Tarn River, France , 2007, Applied and Environmental Microbiology.

[20]  A. Cembella,et al.  Rapid detection of cyanobacterial toxins in precursor ion mode by liquid chromatography tandem mass spectrometry. , 2007, Journal of mass spectrometry : JMS.

[21]  S. Wood,et al.  First report of homoanatoxin-a and associated dog neurotoxicosis in New Zealand. , 2007, Toxicon : official journal of the International Society on Toxinology.

[22]  S. Wood,et al.  Production of anatoxin-a and a novel biosynthetic precursor by the cyanobacterium Aphanizomenon issatschenkoi. , 2007, Environmental science & technology.

[23]  R. Curini,et al.  Simple and rapid determination of anatoxin-a in lake water and fish muscle tissue by liquid-chromatography-tandem mass spectrometry. , 2006, Journal of chromatography. A.

[24]  L. Krienitz,et al.  Toxic cyanobacteria and their toxins in standing waters of Kenya: implications for water resource use. , 2006, Journal of water and health.

[25]  L. Krienitz,et al.  Analysis of the cyanotoxins anatoxin-a and microcystins in Lesser Flamingo feathers , 2006 .

[26]  B. Lau,et al.  Improved method for the determination of anatoxin-a and two of its metabolites in blue-green algae using liquid chromatography with fluorescence detection. , 2005, Journal of AOAC International.

[27]  K. James,et al.  Strategies to avoid the mis-identification of anatoxin-a using mass spectrometry in the forensic investigation of acute neurotoxic poisoning. , 2005, Journal of chromatography. A.

[28]  K. James,et al.  Anatoxins and degradation products, determined using hybrid quadrupole time-of-flight and quadrupole ion-trap mass spectrometry: forensic investigations of cyanobacterial neurotoxin poisoning. , 2005, Rapid communications in mass spectrometry : RCM.

[29]  R. Rippka,et al.  Neurotoxins in axenic oscillatorian cyanobacteria: coexistence of anatoxin-a and homoanatoxin-a determined by ligand-binding assay and GC/MS. , 2005, Microbiology.

[30]  S. Oishi,et al.  Simultaneous production of homoanatoxin-a, anatoxin-a, and a new non-toxic 4-hydroxyhomoanatoxin-a by the cyanobacterium Raphidiopsis mediterranea Skuja. , 2003, Toxicon : official journal of the International Society on Toxinology.

[31]  Kevin J James,et al.  Liquid chromatography with electrospray ion-trap mass spectrometry for the determination of anatoxins in cyanobacteria and drinking water. , 2003, Rapid communications in mass spectrometry : RCM.

[32]  L. Krienitz,et al.  Contribution of hot spring cyanobacteria to the mysterious deaths of Lesser Flamingos at Lake Bogoria, Kenya. , 2003, FEMS microbiology ecology.

[33]  M. Pliński,et al.  Nodularia spumigena blooms and the occurrence of hepatotoxin in the Gulf of Gdańsk , 2003 .

[34]  J. Pawliszyn,et al.  Analysis of anatoxin-a in aqueous samples by solid-phase microextraction coupled to high-performance liquid chromatography with fluorescence detection and on-fiber derivatization. , 2002, Journal of chromatography. A.

[35]  N. Camp,et al.  Synthesis of (+ / -)-Anatoxin-a and Analogues , 2000 .

[36]  M. Takino,et al.  Analysis of anatoxin-a in freshwaters by automated on-line derivatization-liquid chromatography-electrospray mass spectrometry. , 1999, Journal of chromatography. A.

[37]  I. Chorus,et al.  Anatoxin‐a and neurotoxic cyanobacteria in German lakes and reservoirs , 1999 .

[38]  K. James,et al.  Sensitive determination of anatoxin-a, homoanatoxin-a and their degradation products by liquid chromatography with fluorimetric detection. , 1998, Journal of chromatography. A.

[39]  H. Naegeli,et al.  Identification of a microcystin in benthic cyanobacteria linked to cattle deaths on alpine pastures in Switzerland , 1997 .

[40]  H. Mansell Synthetic approaches to anatoxin-a , 1996 .

[41]  S. Wonnacott,et al.  Anatoxin-a-evoked [3H]dopamine release from rat striatal synaptosomes , 1995, Neuropharmacology.

[42]  K. Sivonen,et al.  Biosynthesis of anatoxin-a in Anabaena flos-aquae and homoanatoxin-a in Oscillatoria formosa , 1995 .

[43]  M. Amar,et al.  (+)‐Anatoxin‐a Is a Potent Agonist at Neuronal Nicotinic Acetylcholine Receptors , 1993, Journal of neurochemistry.

[44]  W. Carmichael,et al.  Liquid chromatography/mass spectrometric detection of anatoxin-a, a neurotoxin from cyanobacteria , 1993 .

[45]  P. Brough,et al.  Determination of anatoxin-a and homoanatoxin in blue—green algal extracts by high-performance liquid chromatography and gas chromatography—mass spectrometry , 1993 .

[46]  C. Scrimgeour,et al.  Identification of anatoxin-A in benthic cyanobacteria (blue-green algae) and in associated dog poisonings at Loch Insh, Scotland. , 1992, Toxicon : official journal of the International Society on Toxinology.

[47]  G. Codd,et al.  Fatal attraction to cyanobacteria? , 1992, Nature.

[48]  A. Sirén,et al.  Cardio-respiratory changes and mortality in the conscious rat induced by (+)- and (+/-)-anatoxin-a. , 1992, Toxicon : official journal of the International Society on Toxinology.

[49]  Richard E. Moore,et al.  Investigations of a neurotoxic oscillatorialean strain (Cyanophyceae) and its toxin. Isolation and characterization of homoanatoxin‐a , 1992 .

[50]  D. Stevens,et al.  Stability studies on the cyanobacterial nicotinic alkaloid anatoxin-A. , 1991, Toxicon : official journal of the International Society on Toxinology.

[51]  K. Sivonen,et al.  Preliminary characterization of neurotoxic cyanobacteria blooms and strains from Finland , 1989 .

[52]  W. Carmichael,et al.  A new procedure for the analysis and purification of naturally occurring anatoxin-a from the blue-green alga Anabaena flos-aquae. , 1989, Toxicon : official journal of the International Society on Toxinology.

[53]  K. Himberg Determination of anatoxin-a, the neurotoxin of Anabaena flos-aquae cyanobacterium, in algae and water by gas chromatography-mass spectrometry. , 1989, Journal of chromatography.

[54]  R. Smith,et al.  A rapid analysis of water for anatoxin a, the unstable toxic alkaloid from Anabaena flos-aquae, the stable non-toxic alkaloids left after bioreduction and a related amine which may be nature's precursor to anatoxin a. , 1987, Veterinary and human toxicology.

[55]  H. Rapoport,et al.  Synthetic and conformational studies on anatoxin-a: a potent acetylcholine agonist. , 1985, Journal of medicinal chemistry.

[56]  See Hoi Wong,et al.  Detecting an algal toxin by high-pressure liquid chromatography , 1982 .

[57]  B. Archer,et al.  Simplified Monitoring of Anatoxin-A by Reverse-Phase High Performance Liquid Chromatography and the Sub-Acute Effects of Anatoxin-A in Rats , 1981 .

[58]  E. Albuquerque,et al.  Anatoxin-a: a novel, potent agonist at the nicotinic receptor. , 1980, Molecular pharmacology.

[59]  H. Rapoport,et al.  Synthesis of anatoxin a via intramolecular cyclization of iminium salts , 1979 .

[60]  N. R. Hunter,et al.  Anatoxin-a, a toxic alkaloid from Anabaena flos-aquae NRC-44h , 1977 .

[61]  W. Carmichael,et al.  Toxicology and pharmacological action of anabaena flos-aquae toxin. , 1975, Science.

[62]  W. Carmichael,et al.  AN IMPROVED METHOD FOR OBTAINING AXENIC CLONES OF PLANKTONIC BLUE‐GREEN ALGAE 1, 2 , 1974 .