Hypoglycemic Mechanism of Tegillarca granosa Polysaccharides on Type 2 Diabetic Mice by Altering Gut Microbiota and Regulating the PI3K-Akt Signaling Pathway

[1]  Yong-lin Gao,et al.  Characterization and anti-diabetic evaluation of sulfated polysaccharide from Spirulina platensis , 2022, Journal of Functional Foods.

[2]  Chunqing Ai,et al.  An acidic polysaccharide from Patinopecten yessoensis skirt prevents obesity and improves gut microbiota and metabolism of mice induced by high-fat diet. , 2022, Food research international.

[3]  Bin Liu,et al.  Anti-diabetic effect of aloin via JNK-IRS1/PI3K pathways and regulation of gut microbiota , 2022, Food Science and Human Wellness.

[4]  Yuanfeng Wang,et al.  Liubao brick tea activates the PI3K-Akt signaling pathway to lower blood glucose, metabolic disorders and insulin resistance via altering the intestinal flora. , 2021, Food research international.

[5]  Wei Li,et al.  Immunomodulatory activity of polysaccharide from Arca granosa Linnaeus via TLR4/MyD88/NFκB and TLR4/TRIF signaling pathways , 2021 .

[6]  S. Deng,et al.  Protective effects of Antarctic krill oil in dextran sulfate sodium-induced ulcerative colitis mice , 2021 .

[7]  Guisheng Zhou,et al.  Regulating the gut microbiota and SCFAs in the faeces of T2DM rats should be one of antidiabetic mechanisms of mogrosides in the fruits of Siraitia grosvenorii. , 2021, Journal of ethnopharmacology.

[8]  Chi Zhang,et al.  Effects of soybean protein isolates and peptides on the growth and metabolism of Lactobacillus rhamnosus , 2021 .

[9]  Y. Xin,et al.  Role of the gut microbiota in type 2 diabetes and related diseases. , 2021, Metabolism: clinical and experimental.

[10]  Xianju Huang,et al.  Veratrilla baillonii Franch exerts anti-diabetic activity and improves liver injury through IRS/PI3K/AKT signaling pathways in type 2 diabetic db/db mice , 2020 .

[11]  Jie-lun Hu,et al.  Hypoglycemic and hypolipidemic mechanism of tea polysaccharides on type 2 diabetic rats via gut microbiota and metabolism alteration. , 2020, Journal of agricultural and food chemistry.

[12]  S. Praveen,et al.  Role of nutraceutical starch and proanthocyanidins of pigmented rice in regulating hyperglycemia: Enzyme inhibition, enhanced glucose uptake and hepatic glucose homeostasis using in vitro model. , 2020, Food chemistry.

[13]  M. Dekker Nitert,et al.  Wasabi supplementation alters the composition of the gut microbiota of diet-induced obese rats , 2020 .

[14]  S. Nie,et al.  Antidiabetic effects of polysaccharide from azuki bean (Vigna angularis) in type 2 diabetic rats via insulin/PI3K/AKT signaling pathway , 2020 .

[15]  Jinlong Mao,et al.  Composition, isolation, purification and biological activities of Sargassum fusiforme polysaccharides: A review. , 2020, Carbohydrate polymers.

[16]  Guisheng Zhou,et al.  Anti-hyperglycemic and anti-hyperlipidemic effects of a special fraction of Luohanguo extract on obese T2DM rats. , 2020, Journal of ethnopharmacology.

[17]  Muhammad Rashid Khan,et al.  Antioxidant, anti-inflammatory and hypoglycemic effects of Fagonia olivieri DC on STZ-nicotinamide induced diabetic rats - In vivo and in vitro study. , 2019, Journal of ethnopharmacology.

[18]  M. Rousseau,et al.  High rates of atherogenic dyslipidemia, β-cell function loss, and microangiopathy among Turkish migrants with T2DM. , 2019, Diabetes & metabolic syndrome.

[19]  B. Chun,et al.  Optimization of polysaccharides extraction from Pacific oyster (Crassostrea gigas) using subcritical water: Structural characterization and biological activities. , 2019, International journal of biological macromolecules.

[20]  Hao Wu,et al.  Structural elucidation and immune-enhancing activity of peculiar polysaccharides fractioned from marine clam Meretrix meretrix (Linnaeus). , 2018, Carbohydrate polymers.

[21]  Dave L Dixon,et al.  Glucose‐Lowering Therapies for Cardiovascular Risk Reduction in Type 2 Diabetes Mellitus: State‐of‐the‐Art Review , 2018, Mayo Clinic proceedings.

[22]  Anupama Sharma,et al.  Chlorophyllin supplementation modulates hyperglycemia‐induced oxidative stress and apoptosis in liver of streptozotocin‐administered mice , 2018, BioFactors.

[23]  R. Linhardt,et al.  Comprehensive analysis of glycosaminoglycans from the edible shellfish. , 2018, Carbohydrate polymers.

[24]  Fei-fei Yan,et al.  Diabetes mellitus and Alzheimer’s disease: GSK-3β as a potential link , 2018, Behavioural Brain Research.

[25]  Kaiping Wang,et al.  Dendrobium officinale polysaccharide attenuates type 2 diabetes mellitus via the regulation of PI3K/Akt-mediated glycogen synthesis and glucose metabolism , 2018 .

[26]  Shuxia Wang,et al.  Effect of luteolin on inflammatory responses in RAW264.7 macrophages activated with LPS and IFN-γ , 2017 .

[27]  A. Tahrani,et al.  Pharmacology and therapeutic implications of current drugs for type 2 diabetes mellitus , 2016, Nature Reviews Endocrinology.

[28]  Hiromi Ito,et al.  Impact of taurine depletion on glucose control and insulin secretion in mice. , 2015, Journal of pharmacological sciences.

[29]  Robert R. Henry,et al.  Type 2 diabetes mellitus , 2015, Nature Reviews Disease Primers.

[30]  Qian Liu,et al.  Sulforaphane protects human umbilical vein cells against lipotoxicity by stimulating autophagy via an AMPK-mediated pathway , 2015 .

[31]  Tingting Wang,et al.  Anti-diabetic activity in type 2 diabetic mice and α-glucosidase inhibitory, antioxidant and anti-inflammatory potential of chemically profiled pear peel and pulp extracts (Pyrus spp.) , 2015 .

[32]  Barbara M. Bakker,et al.  Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation , 2015, Diabetes.

[33]  B. Thorens.  GLUT2, glucose sensing and glucose homeostasis , 2015, Diabetologia.

[34]  K. Badri,et al.  Effect of Pterocarpus santalinus bark, on blood glucose, serum lipids, plasma insulin and hepatic carbohydrate metabolic enzymes in streptozotocin-induced diabetic rats. , 2010, Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association.