论文信息 - Nanocapsule formation by interfacial polymer deposition following solvent displacement

Nanocapsule formation by interfacial polymer deposition following solvent displacement

Abstract Indomethacin-loaded nanocapsules were prepared by deposition of poly-( D,L -lactide) polymer at the o/w interface following acetone displacement from the oily nanodroplets. An attempt was made to elucidate the mechanisms of formation in terms of interfacial turbulence between two unequilibrated liquid phases involving flow, diffusion and surface tension decrease (Marangoni effect).

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