Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128

[1]  Zhiwei Wang,et al.  MicroRNA-106b-5p boosts glioma tumorigensis by targeting multiple tumor suppressor genes , 2014, Oncogene.

[2]  Zeng-li Miao,et al.  MicroRNA-210 overexpression predicts poorer prognosis in glioma patients , 2014, Journal of Clinical Neuroscience.

[3]  A. Potapov,et al.  Analysis of expression of microRNAs and genes involved in the control of key signaling mechanisms that support or inhibit development of brain tumors of different grades. , 2014, Clinica chimica acta; international journal of clinical chemistry.

[4]  N. Saini,et al.  Brain microRNAs and insights into biological functions and therapeutic potential of brain enriched miRNA-128 , 2014, Molecular Cancer.

[5]  M. Wolter,et al.  MiR-328 promotes glioma cell invasion via SFRP1-dependent Wnt-signaling activation. , 2014, Neuro-oncology.

[6]  Q. Cheng,et al.  MicroRNA-203 inhibits the proliferation and invasion of U251 glioblastoma cells by directly targeting PLD2. , 2014, Molecular medicine reports.

[7]  Z. Fei,et al.  MicroRNA-34a induces apoptosis in the human glioma cell line, A172, through enhanced ROS production and NOX2 expression. , 2014, Biochemical and biophysical research communications.

[8]  Jianmiao Liu,et al.  MicroRNA-503 acts as a tumor suppressor in glioblastoma for multiple antitumor effects by targeting IGF-1R , 2013, Oncology reports.

[9]  V. Golubovskaya,et al.  MiR-138 and MiR-135 directly target focal adhesion kinase, inhibit cell invasion, and increase sensitivity to chemotherapy in cancer cells. , 2014, Anti-cancer agents in medicinal chemistry.

[10]  Shucheng Ma,et al.  Decreased expression of microRNA-206 correlates with poor clinical outcome in patients with malignant astrocytomas , 2014, Pathology & Oncology Research.

[11]  L. Gong,et al.  MicroRNA-21 expression is associated with overall survival in patients with glioma , 2013, Diagnostic Pathology.

[12]  Dan Chen,et al.  Targeting microRNA-23a to inhibit glioma cell invasion via HOXD10 , 2013, Scientific Reports.

[13]  T. Jiang,et al.  Overexpressed let-7a inhibits glioma cell malignancy by directly targeting K-ras, independently of PTEN. , 2013, Neuro-oncology.

[14]  Xiangdong Li,et al.  microRNA-155 regulates cell proliferation and invasion by targeting FOXO3a in glioma. , 2013, Oncology reports.

[15]  Zhifei Wang,et al.  TFAM is directly regulated by miR-23b in glioma. , 2013, Oncology reports.

[16]  Yiqun Cao,et al.  Decreased miR-106a inhibits glioma cell glucose uptake and proliferation by targeting SLC2A3 in GBM , 2013, BMC Cancer.

[17]  Jing Liu,et al.  miR-146b-5p inhibits glioma migration and invasion by targeting MMP16. , 2013, Cancer letters.

[18]  Shuwei Qiu,et al.  Suppression of tumorigenicity by microRNA-138 through inhibition of EZH2-CDK4/6-pRb-E2F1 signal loop in glioblastoma multiforme. , 2013, Biochimica et biophysica acta.

[19]  A. Shiras,et al.  MiR-145 functions as a tumor-suppressive RNA by targeting Sox9 and adducin 3 in human glioma cells. , 2013, Neuro-oncology.

[20]  Wei Li,et al.  MicroRNA-650 expression in glioma is associated with prognosis of patients , 2013, Journal of Neuro-Oncology.

[21]  Jixiang Liu,et al.  Differential effects of miR-34c-3p and miR-34c-5p on the proliferation, apoptosis and invasion of glioma cells , 2013, Oncology letters.

[22]  Michael C. Ostrowski,et al.  MicroRNA-128 coordinately targets Polycomb Repressor Complexes in glioma stem cells. , 2013, Neuro-oncology.

[23]  Stephen T. C. Wong,et al.  The miR-223/Nuclear Factor I-A Axis Regulates Glial Precursor Proliferation and Tumorigenesis in the CNS , 2013, The Journal of Neuroscience.

[24]  Xiaozhong Peng,et al.  Circadian gene Clock contributes to cell proliferation and migration of glioma and is directly regulated by tumor‐suppressive miR‐124 , 2013, FEBS letters.

[25]  G. Michlewski,et al.  miRNAs in development and pathogenesis of the nervous system. , 2013, Biochemical Society transactions.

[26]  A. Agrawal,et al.  Pro-apoptotic miRNA-128-2 modulates ABCA1, ABCG1 and RXRα expression and cholesterol homeostasis , 2013, Cell Death and Disease.

[27]  Yongming Qiu,et al.  miR-708 acts as a tumor suppressor in human glioblastoma cells. , 2013, Oncology reports.

[28]  Lizhuang Yang,et al.  MiR-124 inhibits the growth of glioblastoma through the downregulation of SOS1. , 2013, Molecular medicine reports.

[29]  C. Kang,et al.  miR-19a and miR-19b Overexpression in Gliomas , 2013, Pathology & Oncology Research.

[30]  Ying Sun,et al.  MiR‐139 Inhibits Mcl‐1 Expression and Potentiates TMZ‐Induced Apoptosis in Glioma , 2013, CNS neuroscience & therapeutics.

[31]  Zhifeng Shi,et al.  MIR‐137 Suppresses Growth and Invasion, is Downregulated in Oligodendroglial Tumors and Targets CSE1L , 2013, Brain pathology.

[32]  Xiaobin Lv,et al.  Downregulation of miRNA‐128 sensitises breast cancer cell to chemodrugs by targeting Bax , 2013, Cell biology international.

[33]  Feng Yan,et al.  MicroRNA-124–Mediated Regulation of Inhibitory Member of Apoptosis-Stimulating Protein of p53 Family in Experimental Stroke , 2013, Stroke.

[34]  Xuemei Chen,et al.  Biogenesis, Turnover, and Mode of Action of Plant MicroRNAs[OPEN] , 2013, Plant Cell.

[35]  L. Kunkel,et al.  Regulation of IRS1/Akt insulin signaling by microRNA-128a during myogenesis , 2013, Journal of Cell Science.

[36]  Minhua Wu,et al.  miR-124 radiosensitizes human glioma cells by targeting CDK4 , 2013, Journal of Neuro-Oncology.

[37]  A. Zechariah,et al.  MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation , 2013, Acta Neuropathologica.

[38]  J. Ai,et al.  miR-143 inhibits glycolysis and depletes stemness of glioblastoma stem-like cells. , 2013, Cancer letters.

[39]  O. Brüstle,et al.  Pluripotent stem cell-derived somatic stem cells as tool to study the role of microRNAs in early human neural development. , 2013, Current molecular medicine.

[40]  K. Somasundaram,et al.  miR-219-5p Inhibits Receptor Tyrosine Kinase Pathway by Targeting EGFR in Glioblastoma , 2013, PloS one.

[41]  G. Schratt,et al.  The DEAH-box helicase DHX36 mediates dendritic localization of the neuronal precursor-microRNA-134. , 2013, Genes & development.

[42]  P. Pu,et al.  miR-92b controls glioma proliferation and invasion through regulating Wnt/beta-catenin signaling via Nemo-like kinase. , 2013, Neuro-oncology.

[43]  B. Trapp,et al.  Hippocampal demyelination and memory dysfunction are associated with increased levels of the neuronal microRNA miR‐124 and reduced AMPA receptors , 2013, Annals of neurology.

[44]  C. Norbury,et al.  The Long and Short of MicroRNA , 2013, Cell.

[45]  S. Hébert,et al.  Co-regulation of intragenic microRNA miR-153 and its host gene Ia-2β: identification of miR-153 target genes with functions related to IA-2β in pancreas and brain , 2013, Diabetologia.

[46]  Shu-Jen Chen,et al.  MicroRNA-495 inhibits proliferation of glioblastoma multiforme cells by downregulating cyclin-dependent kinase 6 , 2013, World Journal of Surgical Oncology.

[47]  T. Mikkelsen,et al.  MicroRNA-137 is downregulated in glioblastoma and inhibits the stemness of glioma stem cells by targeting RTVP-1 , 2013, Oncotarget.

[48]  Z. Meng,et al.  Downregulation of miR-383 promotes glioma cell invasion by targeting insulin-like growth factor 1 receptor , 2013, Medical Oncology.

[49]  Dan Li,et al.  MicroRNA-200b targets CREB1 and suppresses cell growth in human malignant glioma , 2013, Molecular and Cellular Biochemistry.

[50]  D. Iliopoulos,et al.  Functional screen analysis reveals miR-26b and miR-128 as central regulators of pituitary somatomammotrophic tumor growth through activation of the PTEN–AKT pathway , 2013, Oncogene.

[51]  C. Achim,et al.  Modulation of BK Channel by MicroRNA-9 in Neurons After Exposure to HIV and Methamphetamine , 2013, Journal of Neuroimmune Pharmacology.

[52]  P. Wernet,et al.  MicroRNA-Based Promotion of Human Neuronal Differentiation and Subtype Specification , 2013, PloS one.

[53]  C. Niu,et al.  MiR-134 regulates the proliferation and invasion of glioblastoma cells by reducing Nanog expression , 2013, International journal of oncology.

[54]  X. Jiang,et al.  Regulation of μ‐opioid type 1 receptors by microRNA134 in dorsal root ganglion neurons following peripheral inflammation , 2013, European journal of pain.

[55]  N. Saini,et al.  miR-128 exerts pro-apoptotic effect in a p53 transcription-dependent and -independent manner via PUMA-Bak axis , 2013, Cell Death and Disease.

[56]  Qin Xu,et al.  Downregulation of miR-153 contributes to epithelial-mesenchymal transition and tumor metastasis in human epithelial cancer. , 2013, Carcinogenesis.

[57]  V. Calhoun,et al.  Potential Impact of miR-137 and Its Targets in Schizophrenia , 2013, Front. Genet..

[58]  Y. Mo,et al.  miR-7 suppresses brain metastasis of breast cancer stem-like cells by modulating KLF4. , 2013, Cancer research.

[59]  A. Minn,et al.  Targeting of TGFβ signature and its essential component CTGF by miR-18 correlates with improved survival in glioblastoma. , 2013, RNA.

[60]  Chaofeng Liang,et al.  MicroRNA-195 Inhibits the Proliferation of Human Glioma Cells by Directly Targeting Cyclin D1 and Cyclin E1 , 2013, PloS one.

[61]  P. Pu,et al.  MiR-30a-5p Antisense Oligonucleotide Suppresses Glioma Cell Growth by Targeting SEPT7 , 2013, PloS one.

[62]  Jueheng Wu,et al.  Loss of miR-204 expression enhances glioma migration and stem cell-like phenotype. , 2013, Cancer research.

[63]  D. Schiff,et al.  Oncogenic effects of miR-10b in glioblastoma stem cells , 2013, Journal of Neuro-Oncology.

[64]  G. Gao,et al.  Correlation of microrna-372 upregulation with poor prognosis in human glioma , 2013, Diagnostic Pathology.

[65]  Shucheng Ma,et al.  Expression and clinical significance of microRNA-326 in human glioma miR-326 expression in glioma , 2013, Medical Oncology.

[66]  Libing Song,et al.  miR-486 sustains NF-κB activity by disrupting multiple NF-κB-negative feedback loops , 2012, Cell Research.

[67]  Hirotomo TanakaTakashi,et al.  MicroRNA-183 upregulates HIF-1a by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells , 2013 .

[68]  Michael D. Williams Adipose-derived mesenchymal cell derivation, characterization and differentiation for potential use in cell replacement therapy for diabetes , 2013 .

[69]  L. Tsai,et al.  Validation of schizophrenia-associated genes CSMD1, C10orf26, CACNA1C and TCF4 as miR-137 targets , 2013, Molecular Psychiatry.

[70]  D. O’Carroll,et al.  General Principals of miRNA Biogenesis and Regulation in the Brain , 2013, Neuropsychopharmacology.

[71]  T. Graf,et al.  Tissue-specific control of brain-enriched miR-7 biogenesis. , 2013, Genes & development.

[72]  M. Berger,et al.  Expression of miR-124 inhibits growth of medulloblastoma cells. , 2013, Neuro-oncology.

[73]  Daming Zhang,et al.  MicroRNA-153 is tumor suppressive in glioblastoma stem cells , 2013, Molecular Biology Reports.

[74]  E. Kohmura,et al.  MicroRNA-183 upregulates HIF-1α by targeting isocitrate dehydrogenase 2 (IDH2) in glioma cells , 2013, Journal of Neuro-Oncology.

[75]  P. Li,et al.  MicroRNA-107 inhibits glioma cell migration and invasion by modulating Notch2 expression , 2013, Journal of Neuro-Oncology.

[76]  J. Bixby,et al.  MicroRNAs and neuronal development. , 2012, Seminars in fetal & neonatal medicine.

[77]  Ryoichiro Kageyama,et al.  MicroRNA9 regulates neural stem cell differentiation by controlling Hes1 expression dynamics in the developing brain , 2012, Genes to cells : devoted to molecular & cellular mechanisms.

[78]  Xiaozhong Peng,et al.  The CREB-miR-9 Negative Feedback Minicircuitry Coordinates the Migration and Proliferation of Glioma Cells , 2012, PloS one.

[79]  Shucheng Ma,et al.  Increased Expression of microRNA-17 Predicts Poor Prognosis in Human Glioma , 2012, Journal of biomedicine & biotechnology.

[80]  Xiaozhong Peng,et al.  microRNA-214-mediated UBC9 expression in glioma , 2012, BMB reports.

[81]  T. Jiang,et al.  miR-137 is frequently down-regulated in glioblastoma and is a negative regulator of Cox-2. , 2012, European journal of cancer.

[82]  E. Dobrikova,et al.  p38α Mitogen-Activated Protein Kinase Depletion and Repression of Signal Transduction to Translation Machinery by miR-124 and -128 in Neurons , 2012, Molecular and Cellular Biology.

[83]  Yanhong Yu,et al.  miR‐134 inhibits epithelial to mesenchymal transition by targeting FOXM1 in non‐small cell lung cancer cells , 2012, FEBS letters.

[84]  M. Berry,et al.  Expression and regulation of mouse selenoprotein P transcript variants differing in non-coding RNA , 2012, RNA biology.

[85]  E. Doxakis,et al.  Neurofibromin 1 Is a miRNA Target in Neurons , 2012, PloS one.

[86]  Z. Bashir,et al.  MicroRNA-132 regulates recognition memory and synaptic plasticity in the perirhinal cortex , 2012, The European journal of neuroscience.

[87]  Wieland B Huttner,et al.  Convergent repression of Foxp2 3′UTR by miR-9 and miR-132 in embryonic mouse neocortex: implications for radial migration of neurons , 2012, Development.

[88]  Jian-Ping Cai,et al.  Expression of miR-21, miR-31, miR-96 and miR-135b is correlated with the clinical parameters of colorectal cancer. , 2012, Oncology letters.

[89]  G. Mitchell,et al.  MicroRNAs in Insulin Resistance and Obesity , 2012, Experimental diabetes research.

[90]  Eiji Shimizu,et al.  Dihydropyrimidine dehydrogenase (DPD) expression is negatively regulated by certain microRNAs in human lung tissues. , 2012, Lung cancer.

[91]  Jan Baumgart,et al.  miR‐124‐regulated RhoG reduces neuronal process complexity via ELMO/Dock180/Rac1 and Cdc42 signalling , 2012, The EMBO journal.

[92]  B. Ray,et al.  MicroRNA-153 Physiologically Inhibits Expression of Amyloid-β Precursor Protein in Cultured Human Fetal Brain Cells and Is Dysregulated in a Subset of Alzheimer Disease Patients* , 2012, The Journal of Biological Chemistry.

[93]  M. Hussain Micro-RNAs (miRNAs): genomic organisation, biogenesis and mode of action , 2012, Cell and Tissue Research.

[94]  Ying-chao Liu,et al.  MicroRNA-153 negatively regulates the expression of amyloid precursor protein and amyloid precursor-like protein 2 , 2012, Brain Research.

[95]  S. Cohen,et al.  Drosophila miR-124 regulates neuroblast proliferation through its target anachronism , 2012, Development.

[96]  K S Kosik,et al.  Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases , 2012, Oncogene.

[97]  M. Peschanski,et al.  miR-125 potentiates early neural specification of human embryonic stem cells , 2012, Development.

[98]  B. Jiang,et al.  MiR-128 Inhibits Tumor Growth and Angiogenesis by Targeting p70S6K1 , 2012, PloS one.

[99]  Wei Chen,et al.  The miR-124 regulates the expression of BACE1/β-secretase correlated with cell death in Alzheimer's disease. , 2012, Toxicology letters.

[100]  Thierry Arnould,et al.  miR-212/132 expression and functions: within and beyond the neuronal compartment , 2012, Nucleic acids research.

[101]  B. H. Miller,et al.  MicroRNA-132 dysregulation in schizophrenia has implications for both neurodevelopment and adult brain function , 2012, Proceedings of the National Academy of Sciences.

[102]  S. Young,et al.  Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA , 2012, Proceedings of the National Academy of Sciences.

[103]  Gang Lu,et al.  Loss of Brain-enriched miR-124 MicroRNA Enhances Stem-like Traits and Invasiveness of Glioma Cells* , 2012, The Journal of Biological Chemistry.

[104]  P. Muti,et al.  MicroRNA-128-2 targets the transcriptional repressor E2F5 enhancing mutant p53 gain of function , 2011, Cell Death and Differentiation.

[105]  O. Slabý,et al.  MicroRNAs and Glioblastoma , 2012 .

[106]  V. Thayanithy,et al.  Perturbation of 14q32 miRNAs-cMYC gene network in osteosarcoma. , 2012, Bone.

[107]  T. Pizzorusso,et al.  MicroRNA212/132 family: molecular transducer of neuronal function and plasticity. , 2012, The international journal of biochemistry & cell biology.

[108]  A. Dayton,et al.  MicroRNA regulation of STAT4 protein expression: rapid and sensitive modulation of IL-12 signaling in human natural killer cells. , 2011, Blood.

[109]  Tao Wang,et al.  HER2 interacts with CD44 to up-regulate CXCR4 via epigenetic silencing of microRNA-139 in gastric cancer cells. , 2011, Gastroenterology.

[110]  E. Ponomarev,et al.  Visualization and quantitation of the expression of microRNAs and their target genes in neuroblastoma single cells using imaging cytometry , 2011, BMC Research Notes.

[111]  Peng Ye,et al.  miR-137 forms a regulatory loop with nuclear receptor TLX and LSD1 in neural stem cells. , 2011, Nature communications.

[112]  C. Holt,et al.  Regulation of chemotropic guidance of nerve growth cones by microRNA , 2011, Molecular Brain.

[113]  R. Pfundt,et al.  Chromosome 1p21.3 microdeletions comprising DPYD and MIR137 are associated with intellectual disability , 2011, Journal of Medical Genetics.

[114]  Ferdinando Di Cunto,et al.  Coding-Independent Regulation of the Tumor Suppressor PTEN by Competing Endogenous mRNAs , 2011, Cell.

[115]  H. Geekiyanage,et al.  MicroRNA-137/181c Regulates Serine Palmitoyltransferase and In Turn Amyloid β, Novel Targets in Sporadic Alzheimer's Disease , 2011, The Journal of Neuroscience.

[116]  F. Yu,et al.  Reduced miR-128 in Breast Tumor–Initiating Cells Induces Chemotherapeutic Resistance via Bmi-1 and ABCC5 , 2011, Clinical Cancer Research.

[117]  Bryan R. Cullen,et al.  Reduced Expression of Brain-Enriched microRNAs in Glioblastomas Permits Targeted Regulation of a Cell Death Gene , 2011, PloS one.

[118]  D. Watanabe,et al.  miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression , 2011, Nature Neuroscience.

[119]  Li Li,et al.  MicroRNA-mediated conversion of human fibroblasts to neurons , 2011, Nature.

[120]  P. Pandolfi,et al.  A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language? , 2011, Cell.

[121]  Henry Yang,et al.  Stage-specific modulation of cortical neuronal development by Mmu-miR-134. , 2011, Cerebral cortex.

[122]  Andreas Keller,et al.  A specific miRNA signature in the peripheral blood of glioblastoma patients , 2011, Journal of neurochemistry.

[123]  L. Buée,et al.  MicroRNA-132 loss is associated with tau exon 10 inclusion in progressive supranuclear palsy , 2011, Alzheimer's & Dementia.

[124]  L. McCullough,et al.  miR-23a regulation of X-linked inhibitor of apoptosis (XIAP) contributes to sex differences in the response to cerebral ischemia , 2011, Proceedings of the National Academy of Sciences.

[125]  C. Godfraind,et al.  MicroRNA and Target Protein Patterns Reveal Physiopathological Features of Glioma Subtypes , 2011, PloS one.

[126]  Rachid Karam,et al.  Identification of a microRNA that activates gene expression by repressing nonsense-mediated RNA decay. , 2011, Molecular cell.

[127]  Ming Yi,et al.  Human glioma growth is controlled by microRNA-10b. , 2011, Cancer research.

[128]  Hye-Min Jeon,et al.  ID4 imparts chemoresistance and cancer stemness to glioma cells by derepressing miR-9*-mediated suppression of SOX2. , 2011, Cancer research.

[129]  N. Webster,et al.  Gonadotropin-releasing hormone induces miR-132 and miR-212 to regulate cellular morphology and migration in immortalized LbetaT2 pituitary gonadotrope cells. , 2011, Molecular endocrinology.

[130]  H. Feng,et al.  Ginsenoside Rh2 inhibits glioma cell proliferation by targeting microRNA-128 , 2011, Acta Pharmacologica Sinica.

[131]  Yuri Kotliarov,et al.  Prediction of Associations between microRNAs and Gene Expression in Glioma Biology , 2011, PloS one.

[132]  C. Perez-Iratxeta,et al.  miRNA-132 orchestrates chromatin remodeling and translational control of the circadian clock. , 2011, Human molecular genetics.

[133]  Jung-Eun Park,et al.  Altered microRNA regulation in Huntington's disease models , 2011, Experimental Neurology.

[134]  S. Hammond,et al.  miR-29b is activated during neuronal maturation and targets BH3-only genes to restrict apoptosis. , 2011, Genes & development.

[135]  Jane Y. Wu,et al.  MiR-124 regulates early neurogenesis in the optic vesicle and forebrain, targeting NeuroD1 , 2010, Nucleic acids research.

[136]  Ana Kozomara,et al.  miRBase: integrating microRNA annotation and deep-sequencing data , 2010, Nucleic Acids Res..

[137]  H. Weiner,et al.  MicroRNA-124 promotes microglia quiescence and suppresses EAE by deactivating macrophages via the C/EBP-α–PU.1 pathway , 2011, Nature Medicine.

[138]  N. Saini,et al.  MicroRNA-128 downregulates Bax and induces apoptosis in human embryonic kidney cells , 2011, Cellular and Molecular Life Sciences.

[139]  X. Estivill,et al.  Overexpression of miR-128 specifically inhibits the truncated isoform of NTRK3 and upregulates BCL2 in SH-SY5Y neuroblastoma cells , 2010, BMC Molecular Biology.

[140]  Jun Li,et al.  miR-218 inhibits the invasive ability of glioma cells by direct downregulation of IKK-β. , 2010, Biochemical and biophysical research communications.

[141]  Peter T Nelson,et al.  The miR-15/107 group of microRNA genes: evolutionary biology, cellular functions, and roles in human diseases. , 2010, Journal of molecular biology.

[142]  W. Filipowicz,et al.  The widespread regulation of microRNA biogenesis, function and decay , 2010, Nature Reviews Genetics.

[143]  L. Tsai,et al.  A novel pathway regulates memory and plasticity via SIRT1 and miR-134 , 2010, Nature.

[144]  David W. Taylor,et al.  A Novel miRNA Processing Pathway Independent of Dicer Requires Argonaute2 Catalytic Activity , 2010, Science.

[145]  R. Vibhakar,et al.  MicroRNA 128a Increases Intracellular ROS Level by Targeting Bmi-1 and Inhibits Medulloblastoma Cancer Cell Growth by Promoting Senescence , 2010, PloS one.

[146]  G. Hannon,et al.  A dicer-independent miRNA biogenesis pathway that requires Ago catalysis , 2010, Nature.

[147]  Menggui Huang,et al.  Wnt1-cre-mediated conditional loss of Dicer results in malformation of the midbrain and cerebellum and failure of neural crest and dopaminergic differentiation in mice. , 2010, Journal of molecular cell biology.

[148]  P. Jin,et al.  MicroRNA miR‐137 Regulates Neuronal Maturation by Targeting Ubiquitin Ligase Mind Bomb‐1 , 2010, Stem cells.

[149]  Nicholas T. Ingolia,et al.  Mammalian microRNAs predominantly act to decrease target mRNA levels , 2010, Nature.

[150]  R. Knight,et al.  miR-7 and miR-214 are specifically expressed during neuroblastoma differentiation, cortical development and embryonic stem cells differentiation, and control neurite outgrowth in vitro. , 2010, Biochemical and biophysical research communications.

[151]  D. Arvanitis,et al.  Ephrin-B1 Reverse Signaling Controls a Posttranscriptional Feedback Mechanism via miR-124 , 2010, Molecular and Cellular Biology.

[152]  Michael T. McManus,et al.  Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination , 2010, Neuron.

[153]  Q. Lu,et al.  MicroRNA-Mediated Control of Oligodendrocyte Differentiation , 2010, Neuron.

[154]  Ji Wan,et al.  Structure and activity of putative intronic miRNA promoters. , 2010, RNA.

[155]  F. Eisenhaber,et al.  RNAase-III enzyme Dicer maintains signaling pathways for differentiation and survival in mouse cortical neural stem cells , 2010, Journal of Cell Science.

[156]  E. Chiocca,et al.  MicroRNAs and glioblastoma; the stem cell connection , 2010, Cell Death and Differentiation.

[157]  Mei Mei,et al.  Downregulation of miR-21 inhibits EGFR pathway and suppresses the growth of human glioblastoma cells independent of PTEN status , 2010, Laboratory Investigation.

[158]  P. Sharp,et al.  Regulation of Synaptic Structure and Function by FMRP-Associated MicroRNAs miR-125 b and miR-132 , 2010 .

[159]  Epaminondas Doxakis,et al.  Post-transcriptional Regulation of α-Synuclein Expression by mir-7 and mir-153 , 2010, The Journal of Biological Chemistry.

[160]  M. Laan,et al.  MicroRNAs miR-124 and miR-135a are potential regulators of the mineralocorticoid receptor gene (NR3C2) expression , 2010, Biochemical and biophysical research communications.

[161]  Lara J. Monteiro,et al.  Definition of microRNAs that repress expression of the tumor suppressor gene FOXO1 in endometrial cancer. , 2009, Cancer research.

[162]  Chiwai Wong,et al.  Downregulations of B‐cell lymphoma 2 and myeloid cell leukemia sequence 1 by microRNA 153 induce apoptosis in a glioblastoma cell line DBTRG‐05MG , 2009, International journal of cancer.

[163]  E. Doxakis POST-TRANSCRIPTIONAL REGULATION OF ALPHA-SYNUCLEIN EXPRESSION BY MIR-7 AND MIR-153 , 2010 .

[164]  J. Michálek,et al.  MicroRNA-181 family predicts response to concomitant chemoradiotherapy with temozolomide in glioblastoma patients. , 2010, Neoplasma.

[165]  P. Sethi,et al.  Micro-RNA-128 (miRNA-128) down-regulation in glioblastoma targets ARP5 (ANGPTL6), Bmi-1 and E2F-3a, key regulators of brain cell proliferation , 2010, Journal of Neuro-Oncology.

[166]  H. Manji,et al.  Investigation of post-transcriptional gene regulatory networks associated with autism spectrum disorders by microRNA expression profiling of lymphoblastoid cell lines , 2010, Genome Medicine.

[167]  Yate-Ching Yuan,et al.  The role of microRNA-128a in regulating TGFbeta signaling in letrozole-resistant breast cancer cells , 2010, Breast Cancer Research and Treatment.

[168]  E. Van Obberghen,et al.  miR-139 impacts FoxO1 action by decreasing FoxO1 protein in mouse hepatocytes. , 2009, Biochemical and biophysical research communications.

[169]  H. Soreq,et al.  MicroRNA-132 potentiates cholinergic anti-inflammatory signaling by targeting acetylcholinesterase. , 2009, Immunity.

[170]  Michael T. McManus,et al.  Dicer ablation in oligodendrocytes provokes neuronal impairment in mice , 2009, Annals of neurology.

[171]  Giuseppe Giannini,et al.  MiR‐128 up‐regulation inhibits Reelin and DCX expression and reduces neuroblastoma cell motility and invasiveness , 2009, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[172]  K. Kosik,et al.  MicroRNAs Potentiate Neural Development , 2009, Neuron.

[173]  Alexey I Nesvizhskii,et al.  Quantitative Proteomic Profiling of Prostate Cancer Reveals a Role for miR-128 in Prostate Cancer* , 2009, Molecular & Cellular Proteomics.

[174]  K. Waters,et al.  MicroRNA 132 regulates nutritional stress-induced chemokine production through repression of SirT1. , 2009, Molecular endocrinology.

[175]  Shu Zheng,et al.  Epidermal growth factor receptor-regulated miR-125a-5p – a metastatic inhibitor of lung cancer , 2009, The FEBS journal.

[176]  Xiangyin Kong,et al.  miR-124 is frequently down-regulated in medulloblastoma and is a negative regulator of SLC16A1. , 2009, Human pathology.

[177]  J. Im,et al.  Repression of α-synuclein expression and toxicity by microRNA-7 , 2009, Proceedings of the National Academy of Sciences.

[178]  Qian Wang,et al.  Bead‐based microarray analysis of microRNA expression in hepatocellular carcinoma: miR‐338 is downregulated , 2009, Hepatology research : the official journal of the Japan Society of Hepatology.

[179]  D. Kaufer,et al.  Mechanisms , 2009, Superconducting State.

[180]  G. Crabtree,et al.  MicroRNA-mediated switching of chromatin-remodelling complexes in neural development , 2009, Nature.

[181]  M. McPeek,et al.  MicroRNAs and metazoan macroevolution: insights into canalization, complexity, and the Cambrian explosion , 2009, BioEssays : news and reviews in molecular, cellular and developmental biology.

[182]  Francisco Tirado,et al.  GeneCodis: interpreting gene lists through enrichment analysis and integration of diverse biological information , 2009, Nucleic Acids Res..

[183]  Z. Weng,et al.  Collapse of Germline piRNAs in the Absence of Argonaute3 Reveals Somatic piRNAs in Flies , 2009, Cell.

[184]  Claes Wahlestedt,et al.  MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction , 2009, Proceedings of the National Academy of Sciences.

[185]  Guoqiang Sun,et al.  A feedback regulatory loop involving microRNA-9 and nuclear receptor TLX in neural stem cell fate determination , 2009, Nature Structural &Molecular Biology.

[186]  Ying-Hui Fu,et al.  miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination , 2009, Disease Models & Mechanisms.

[187]  Fedor V. Karginov,et al.  The miR-17∼92 cluster collaborates with the Sonic Hedgehog pathway in medulloblastoma , 2009, Proceedings of the National Academy of Sciences.

[188]  Steven W. Flavell,et al.  Mef2-mediated transcription of the miR379–410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels , 2009, The EMBO journal.

[189]  N. Lynam‐Lennon,et al.  The roles of microRNA in cancer and apoptosis , 2009, Biological reviews of the Cambridge Philosophical Society.

[190]  Yan Zeng,et al.  Regulation of the Mammalian Nervous System by MicroRNAs , 2009, Molecular Pharmacology.

[191]  D. Bartel MicroRNAs: Target Recognition and Regulatory Functions , 2009, Cell.

[192]  S. Armstrong,et al.  miR-128b is a potent glucocorticoid sensitizer in MLL-AF4 acute lymphocytic leukemia cells and exerts cooperative effects with miR-221. , 2008, Blood.

[193]  Yadong Wang,et al.  miR2Disease: a manually curated database for microRNA deregulation in human disease , 2008, Nucleic Acids Res..

[194]  Christiane Haffner,et al.  miRNAs are essential for survival and differentiation of newborn neurons but not for expansion of neural progenitors during early neurogenesis in the mouse embryonic neocortex , 2008, Development.

[195]  Agnieszka Bronisz,et al.  Targeting of the Bmi-1 oncogene/stem cell renewal factor by microRNA-128 inhibits glioma proliferation and self-renewal. , 2008, Cancer research.

[196]  S. Booth,et al.  A miRNA Signature of Prion Induced Neurodegeneration , 2008, PloS one.

[197]  Yvonne Tay,et al.  MicroRNAs to Nanog, Oct4 and Sox2 coding regions modulate embryonic stem cell differentiation , 2008, Nature.

[198]  G. Stein,et al.  A microRNA signature for a BMP2-induced osteoblast lineage commitment program , 2008, Proceedings of the National Academy of Sciences.

[199]  John W M Martens,et al.  Four miRNAs associated with aggressiveness of lymph node-negative, estrogen receptor-positive human breast cancer , 2008, Proceedings of the National Academy of Sciences.

[200]  Kamel Khalili,et al.  Inhibition of SNAP25 expression by HIV‐1 Tat involves the activity of mir‐128a , 2008, Journal of cellular physiology.

[201]  G. Schratt,et al.  MicroRNA function in neuronal development, plasticity and disease. , 2008, Biochimica et biophysica acta.

[202]  Reuven Agami,et al.  Regulation of the adenomatous polyposis coli gene by the miR-135 family in colorectal cancer. , 2008, Cancer research.

[203]  G. Schratt,et al.  microRNAs: tiny regulators of synapse function in development and disease , 2008, Journal of cellular and molecular medicine.

[204]  D. Geschwind,et al.  Heterogeneous dysregulation of microRNAs across the autism spectrum , 2008, neurogenetics.

[205]  Hideaki Ando,et al.  An activity-regulated microRNA controls dendritic plasticity by down-regulating p250GAP , 2008, Proceedings of the National Academy of Sciences.

[206]  Claudia Petritsch,et al.  miR-124 and miR-137 inhibit proliferation of glioblastoma multiforme cells and induce differentiation of brain tumor stem cells , 2008 .

[207]  F. Hirsch,et al.  EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines. , 2008, Annals of oncology : official journal of the European Society for Medical Oncology.

[208]  Paul Pavlidis,et al.  Altered brain microRNA biogenesis contributes to phenotypic deficits in a 22q11-deletion mouse model , 2008, Nature Genetics.

[209]  U. A. Ørom,et al.  MicroRNA-10a binds the 5'UTR of ribosomal protein mRNAs and enhances their translation. , 2008, Molecular cell.

[210]  Yunqing Li,et al.  microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma. , 2008, Cancer research.

[211]  Manfred Kunz,et al.  MicroRNA let-7b targets important cell cycle molecules in malignant melanoma cells and interferes with anchorage-independent growth , 2008, Cell Research.

[212]  Jidong Liu,et al.  Control of protein synthesis and mRNA degradation by microRNAs. , 2008, Current opinion in cell biology.

[213]  J. Inazawa,et al.  Exploration of tumor-suppressive microRNAs silenced by DNA hypermethylation in oral cancer. , 2008, Cancer research.

[214]  Elaine Fuchs,et al.  A skin microRNA promotes differentiation by repressing ‘stemness’ , 2008, Nature.

[215]  H. Ruohola-Baker,et al.  Small RNAs: Keeping Stem Cells in Line , 2008, Cell.

[216]  J. George,et al.  MicroRNA‐134 Modulates the Differentiation of Mouse Embryonic Stem Cells, Where It Causes Post‐Transcriptional Attenuation of Nanog and LRH1 , 2008, Stem cells.

[217]  A. Roses,et al.  Identification of miRNA Changes in Alzheimer's Disease Brain and CSF Yields Putative Biomarkers and Insights into Disease Pathways , 2008 .

[218]  Wei Liu,et al.  MicroRNA-128 inhibits glioma cells proliferation by targeting transcription factor E2F3a , 2008, Journal of Molecular Medicine.

[219]  R. Maggi,et al.  Retinoic acid reduces human neuroblastoma cell migration and invasiveness: effects on DCX, LIS1, neurofilaments-68 and vimentin expression , 2008, BMC Cancer.

[220]  T. Golub,et al.  MicroRNA expression signatures accurately discriminate acute lymphoblastic leukemia from acute myeloid leukemia , 2007, Proceedings of the National Academy of Sciences.

[221]  M. Latronico,et al.  Emerging role of microRNAs in cardiovascular biology. , 2007, Circulation research.

[222]  Gail Mandel,et al.  Homeostatic regulation of MeCP2 expression by a CREB-induced microRNA , 2007, Nature Neuroscience.

[223]  Sam Griffiths-Jones,et al.  Annotating noncoding RNA genes. , 2007, Annual review of genomics and human genetics.

[224]  Ole A. Andreassen,et al.  Brain Expressed microRNAs Implicated in Schizophrenia Etiology , 2007, PloS one.

[225]  T. Maniatis,et al.  The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. , 2007, Molecular cell.

[226]  E. Lai,et al.  The Mirtron Pathway Generates microRNA-Class Regulatory RNAs in Drosophila , 2007, Cell.

[227]  P. Janson,et al.  MicroRNAs: Novel Regulators Involved in the Pathogenesis of Psoriasis? , 2007, PloS one.

[228]  P. Greengard,et al.  Cerebellar neurodegeneration in the absence of microRNAs , 2007, The Journal of experimental medicine.

[229]  B. Scheithauer,et al.  The 2007 WHO classification of tumours of the central nervous system , 2007, Acta Neuropathologica.

[230]  L. Lim,et al.  MicroRNA targeting specificity in mammals: determinants beyond seed pairing. , 2007, Molecular cell.

[231]  C. Sander,et al.  A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing , 2007, Cell.

[232]  A. Hackam,et al.  Human embryonic and neuronal stem cell markers in retinoblastoma , 2007, Molecular vision.

[233]  John T. Dimos,et al.  shRNA knockdown of Bmi-1 reveals a critical role for p21-Rb pathway in NSC self-renewal during development. , 2007, Cell stem cell.

[234]  Takanobu Nakazawa,et al.  microRNA Modulation of Circadian-Clock Period and Entrainment , 2007, Neuron.

[235]  C. Croce,et al.  MicroRNA expression patterns to differentiate pancreatic adenocarcinoma from normal pancreas and chronic pancreatitis. , 2007, JAMA.

[236]  Jae W. Lee,et al.  The microRNA miR-124 antagonizes the anti-neural REST/SCP1 pathway during embryonic CNS development. , 2007, Genes & development.

[237]  W. Filipowicz,et al.  Repression of protein synthesis by miRNAs: how many mechanisms? , 2007, Trends in cell biology.

[238]  S. Morini,et al.  Reelin expression in human prostate cancer: a marker of tumor aggressiveness based on correlation with grade , 2007, Modern Pathology.

[239]  W. Lukiw,et al.  Micro-RNA speciation in fetal, adult and Alzheimer's disease hippocampus , 2007, Neuroreport.

[240]  V. Kim,et al.  Processing of intronic microRNAs , 2007, The EMBO journal.

[241]  George A Calin,et al.  Identification of differentially expressed microRNAs by microarray: A possible role for microRNA genes in pituitary adenomas , 2007, Journal of cellular physiology.

[242]  Miao Sun,et al.  MicroRNA and cancer: Current status and prospective , 2006, International journal of cancer.

[243]  C. Croce,et al.  MicroRNA-cancer connection: the beginning of a new tale. , 2006, Cancer research.

[244]  T. Okanoue,et al.  Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues , 2006, Oncogene.

[245]  F. Slack,et al.  Oncomirs — microRNAs with a role in cancer , 2006, Nature Reviews Cancer.

[246]  J. Weiler,et al.  Anti-miRNA oligonucleotides (AMOs): ammunition to target miRNAs implicated in human disease? , 2006, Gene Therapy.

[247]  Gail Mandel,et al.  Reciprocal actions of REST and a microRNA promote neuronal identity , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[248]  C. Croce,et al.  A microRNA expression signature of human solid tumors defines cancer gene targets , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[249]  Michael E. Greenberg,et al.  A brain-specific microRNA regulates dendritic spine development , 2006, Nature.

[250]  Olga Varlamova,et al.  Erratum: A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis (Proceedings of the National Academy of Sciences of the United States of America (November 8, 2005) 102, 45 (16426-16431) DOI: 10.1073/pnas.0508448102) , 2006 .

[251]  Peter Tontonoz,et al.  Nuclear receptors in lipid metabolism: targeting the heart of dyslipidemia. , 2006, Annual review of medicine.

[252]  George A. Calin,et al.  Mammalian microRNAs: a small world for fine-tuning gene expression , 2006, Mammalian Genome.

[253]  Vinod Scaria,et al.  Targets for human encoded microRNAs in HIV genes. , 2005, Biochemical and biophysical research communications.

[254]  Xantha Karp,et al.  Encountering MicroRNAs in Cell Fate Signaling , 2005, Science.

[255]  Olga Varlamova,et al.  A cAMP-response element binding protein-induced microRNA regulates neuronal morphogenesis. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[256]  G. Maira,et al.  Extensive modulation of a set of microRNAs in primary glioblastoma. , 2005, Biochemical and biophysical research communications.

[257]  C. Croce,et al.  MicroRNA gene expression deregulation in human breast cancer. , 2005, Cancer research.

[258]  C. Croce,et al.  miRNAs, Cancer, and Stem Cell Division , 2005, Cell.

[259]  K. Kosik,et al.  MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. , 2005, Cancer research.

[260]  Vincent L. Chiang,et al.  Novel and Mechanical Stress–Responsive MicroRNAs in Populus trichocarpa That Are Absent from Arabidopsisw⃞ , 2005, The Plant Cell Online.

[261]  S. Morrison,et al.  Bmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways. , 2005, Genes & development.

[262]  P. Kleihues,et al.  Population-based studies on incidence, survival rates, and genetic alterations in astrocytic and oligodendroglial gliomas. , 2005, Journal of neuropathology and experimental neurology.

[263]  Anton J. Enright,et al.  Materials and Methods Figs. S1 to S4 Tables S1 to S5 References and Notes Micrornas Regulate Brain Morphogenesis in Zebrafish , 2022 .

[264]  Lena Smirnova,et al.  Regulation of miRNA expression during neural cell specification , 2005, The European journal of neuroscience.

[265]  Mark Gerstein,et al.  The temporal patterning microRNA let-7 regulates several transcription factors at the larval to adult transition in C. elegans. , 2005, Developmental cell.

[266]  M. Byrom,et al.  Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and apoptosis , 2005, Nucleic acids research.

[267]  J. Castle,et al.  Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs , 2005, Nature.

[268]  V. Kim,et al.  The Drosha-DGCR8 complex in primary microRNA processing. , 2004, Genes & development.

[269]  R. Shiekhattar,et al.  The Microprocessor complex mediates the genesis of microRNAs , 2004, Nature.

[270]  A. Bradley,et al.  Identification of mammalian microRNA host genes and transcription units. , 2004, Genome research.

[271]  T. Tuschl,et al.  Mechanisms of gene silencing by double-stranded RNA , 2004, Nature.

[272]  Pasko Rakic,et al.  Microarray analysis of microRNA expression in the developing mammalian brain , 2004, Genome Biology.

[273]  U. Kutay,et al.  Nuclear Export of MicroRNA Precursors , 2004, Science.

[274]  D. Bartel,et al.  MicroRNAs Modulate Hematopoietic Lineage Differentiation , 2004, Science.

[275]  V. Ambros,et al.  Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation , 2004, Genome Biology.

[276]  V. Kim,et al.  The nuclear RNase III Drosha initiates microRNA processing , 2003, Nature.

[277]  M. Campbell,et al.  PANTHER: a library of protein families and subfamilies indexed by function. , 2003, Genome research.

[278]  A. Goffinet,et al.  Reelin and brain development , 2003, Nature Reviews Neuroscience.

[279]  A. Rougvie,et al.  The Caenorhabditis elegans hunchback-like gene lin-57/hbl-1 controls developmental time and is regulated by microRNAs. , 2003, Developmental cell.

[280]  Zhihua Liu,et al.  CASK and its target gene Reelin were co-upregulated in human esophageal carcinoma. , 2002, Cancer letters.

[281]  Joseph L Goldstein,et al.  SREBPs: activators of the complete program of cholesterol and fatty acid synthesis in the liver. , 2002, The Journal of clinical investigation.

[282]  Y Li,et al.  [Mitochondria and apoptosis]. , 2000, Zhonghua yu fang yi xue za zhi [Chinese journal of preventive medicine].

[283]  F. Slack,et al.  The lin-41 RBCC gene acts in the C. elegans heterochronic pathway between the let-7 regulatory RNA and the LIN-29 transcription factor. , 2000, Molecular cell.

[284]  Y. Berwald‐Netter,et al.  A Novel CNS Gene Required for Neuronal Migration and Involved in X-Linked Subcortical Laminar Heterotopia and Lissencephaly Syndrome , 1998, Cell.

[285]  G. Ruvkun,et al.  Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans , 1993, Cell.

[286]  V. Ambros,et al.  The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14 , 1993, Cell.

[287]  A. Strasser,et al.  Novel primitive lymphoid tumours induced in transgenic mice by cooperation between myc and bcl-2 , 1990, Nature.