Small Molecule Inhibition of cAMP Response Element Binding Protein in Human Acute Myeloid Leukemia Cells

[1]  K. Klempnauer,et al.  Naphthol AS-E Phosphate Inhibits the Activity of the Transcription Factor Myb by Blocking the Interaction with the KIX Domain of the Coactivator p300 , 2015, Molecular Cancer Therapeutics.

[2]  Yan Gao,et al.  A small-molecule inhibitor of the aberrant transcription factor CBFβ-SMMHC delays leukemia in mice , 2015, Science.

[3]  K. Sakamoto,et al.  Replication factor C3 is a CREB Target Gene that Regulates Cell Cycle Progression through Modulation of Chromatin Loading of PCNA , 2014, Leukemia.

[4]  T. Kawashima,et al.  Health conditions and quality of life in survivors of childhood acute myeloid leukemia comparing post remission chemotherapy to BMT: A report from the children's oncology group , 2014, Pediatric blood & cancer.

[5]  Bingbing X. Li,et al.  Identification, synthesis and evaluation of substituted benzofurazans as inhibitors of CREB-mediated gene transcription. , 2013, Bioorganic & medicinal chemistry letters.

[6]  C. Nguyên,et al.  Small molecule inhibition of CBP/catenin interactions eliminates drug resistant clones in acute lymphoblastic leukemia , 2013, Oncogene.

[7]  Sean C. Bendall,et al.  Normalization of mass cytometry data with bead standards , 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[8]  G. Basso,et al.  MicroRNA-34b promoter hypermethylation induces CREB overexpression and contributes to myeloid transformation , 2013, Haematologica.

[9]  F. Ferrara,et al.  Acute myeloid leukaemia in adults , 2013, The Lancet.

[10]  David G Hendrickson,et al.  Differential analysis of gene regulation at transcript resolution with RNA-seq , 2012, Nature Biotechnology.

[11]  Kinrin Yamanaka,et al.  Structure-activity relationship studies of naphthol AS-E and its derivatives as anticancer agents by inhibiting CREB-mediated gene transcription. , 2012, Bioorganic & medicinal chemistry.

[12]  D. Johnston,et al.  Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel. , 2012, Blood.

[13]  M. Pellegrini,et al.  Reorganization of the host epigenome by a viral oncogene , 2012, Genome research.

[14]  Erin F. Simonds,et al.  A platinum‐based covalent viability reagent for single‐cell mass cytometry , 2012, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[15]  Min Jiang,et al.  Design, synthesis, and biological evaluation of conformationally constrained analogues of naphthol AS-E as inhibitors of CREB-mediated gene transcription. , 2012, Journal of medicinal chemistry.

[16]  Jolanta Grembecka,et al.  Menin-MLL inhibitors reverse oncogenic activity of MLL fusion proteins in leukemia. , 2012, Nature chemical biology.

[17]  H. Miettinen.  Regulation of Human Formyl Peptide Receptor 1 Synthesis: Role of Single Nucleotide Polymorphisms, Transcription Factors, and Inflammatory Mediators , 2011, PloS one.

[18]  J. van Helden,et al.  RSAT peak-motifs: motif analysis in full-size ChIP-seq datasets , 2011, Nucleic acids research.

[19]  Sean C. Bendall,et al.  Single-Cell Mass Cytometry of Differential Immune and Drug Responses Across a Human Hematopoietic Continuum , 2011, Science.

[20]  I. Weissman,et al.  Human acute myelogenous leukemia stem cells revisited: there's more than meets the eye. , 2011, Cancer cell.

[21]  Bingbing X. Li,et al.  Discovery of a Small‐Molecule Inhibitor of the KIX–KID Interaction , 2009, Chembiochem : a European journal of chemical biology.

[22]  Lior Pachter,et al.  Sequence Analysis , 2020, Definitions.

[23]  V. Noé,et al.  Transcriptional regulation of the 5'-flanking region of the human transcription factor Sp3 gene by NF-1, c-Myb, B-Myb, AP-1 and E2F. , 2008, Biochimica et biophysica acta.

[24]  K. Sakamoto,et al.  CREB is a critical regulator of normal hematopoiesis and leukemogenesis. , 2008, Blood.

[25]  G. Basso,et al.  cAMP response element binding protein (CREB) overexpression CREB has been described as critical for leukemia progression , 2007, Haematologica.

[26]  John Calvin Reed,et al.  Mechanisms of apoptosis sensitivity and resistance to the BH3 mimetic ABT-737 in acute myeloid leukemia. , 2006, Cancer cell.

[27]  K. Sakamoto,et al.  Role of cyclic AMP response element binding protein in human leukemias , 2005, Cancer.

[28]  M. Conkright,et al.  CREB: the unindicted cancer co-conspirator. , 2005, Trends in cell biology.

[29]  D. Gilliland,et al.  Drug therapy for acute myeloid leukemia. , 2005, Blood.

[30]  N. Rao,et al.  The role of CREB as a proto-oncogene in hematopoiesis and in acute myeloid leukemia. , 2005, Cancer cell.

[31]  Richard G. Jenner,et al.  Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[32]  K. Gardner,et al.  Identification of small-molecule antagonists that inhibit an activator: coactivator interaction. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[33]  B. Vanwinkle,et al.  Diazoxide-mediated Preconditioning against Apoptosis Involves Activation of cAMP-response Element-binding Protein (CREB) and NFκB* , 2004, Journal of Biological Chemistry.

[34]  A. Loonen,et al.  An Extracellular Signal-Regulated Kinase 1- and 2-Dependent Program of Chromatin Trafficking of c-Fos and Fra-1 Is Required for Cyclin D1 Expression during Cell Cycle Reentry , 2004, Molecular and Cellular Biology.

[35]  M. Inouye,et al.  Transcriptional regulation of the human NaPi-IIb cotransporter by EGF in Caco-2 cells involves c-myb. , 2003, American journal of physiology. Cell physiology.

[36]  R. Hipskind,et al.  Oct-1 Potentiates CREB-Driven Cyclin D1 Promoter Activation via a Phospho-CREB- and CREB Binding Protein-Independent Mechanism , 2002, Molecular and Cellular Biology.

[37]  C. Ball,et al.  Identification of genes periodically expressed in the human cell cycle and their expression in tumors. , 2002, Molecular biology of the cell.

[38]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[39]  R. Goodman,et al.  CREB-binding Protein and p300 in Transcriptional Regulation* , 2001, The Journal of Biological Chemistry.

[40]  J. Blenis,et al.  Granulocyte-macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK. , 2000, Blood.

[41]  Min-Liang Kuo,et al.  The Antiapoptotic Gene mcl-1 Is Up-Regulated by the Phosphatidylinositol 3-Kinase/Akt Signaling Pathway through a Transcription Factor Complex Containing CREB , 1999, Molecular and Cellular Biology.

[42]  H. Dyson,et al.  Structural analyses of CREB-CBP transcriptional activator-coactivator complexes by NMR spectroscopy: implications for mapping the boundaries of structural domains. , 1999, Journal of molecular biology.

[43]  Peter E Wright,et al.  Solution Structure of the KIX Domain of CBP Bound to the Transactivation Domain of CREB: A Model for Activator:Coactivator Interactions , 1997, Cell.

[44]  J. Dick,et al.  Human acute myeloid leukemia is organized as a hierarchy that originates from a primitive hematopoietic cell , 1997, Nature Medicine.

[45]  K. Sakamoto,et al.  Granulocyte-Macrophage Colony-stimulating Factor Induces the Transcriptional Activation of egr-1 through a Protein Kinase A-independent Signaling Pathway (*) , 1995, The Journal of Biological Chemistry.

[46]  M Naguib,et al.  Analysis of drug interactions. , 1995, Anesthesia and analgesia.

[47]  C. Molina,et al.  Cell cycle regulation of cyclin A gene expression by the cyclic AMP-responsive transcription factors CREB and CREM , 1995, Molecular and cellular biology.

[48]  H. Lee,et al.  Granulocyte-macrophage colony-stimulating factor and interleukin-3 signaling pathways converge on the CREB-binding site in the human egr-1 promoter , 1994, Molecular and cellular biology.

[49]  D. Pattabiraman,et al.  Role and potential for therapeutic targeting of MYB in leukemia , 2013, Leukemia.

[50]  Matthew Greenwood,et al.  Anti-apoptosis and cell survival: a review. , 2011, Biochimica et biophysica acta.