Age Changes of EEG during Photo- and Auditory Low-Frequency Stimulation and Assessment of fatigue

This research aimed to find age changes of electrical activity during photo- and audio-stimulation 2, 4, 8, 16-Hz, most useful in clinical EEG. Young and Old healthy peers participated in our study. We used “cognitive space” construction method to visualize how close/distant these emotional sounds are according to EEG data. We analysed EEG distances to find correlation with accompanying to EEG changes behavioural changes, possibly related to aging. Our results demonstrated that young people had more pronounced EEG response to photo-stimulation compared than elderly persons. EEG changes to auditory stimuli in older persons are better differentiated from each other and correlated with fatigue scores. The parameters of EEG variability (fractal dimension, frequency and standard deviation of envelope and Hjorth Parameters) were higher in older participants.

[1]  M. Könönen,et al.  Blocking of EEG alpha activity during visual performance in healthy adults. A quantitative study. , 1993, Electroencephalography and clinical neurophysiology.

[2]  A. Roik,et al.  A Neurophysiological Model of the Cognitive Space , 2013, Neuroscience and Behavioral Physiology.

[3]  Christoph M. Michel,et al.  The behavioral significance of coherent resting-state oscillations after stroke , 2012, NeuroImage.

[4]  B. Westmoreland.  Normal and Benign Eeg Patterns , 1982 .

[5]  E. Niedermeyer.  Alpha rhythms as physiological and abnormal phenomena. , 1997, International journal of psychophysiology : official journal of the International Organization of Psychophysiology.

[6]  P. A. Valentine,et al.  Sensory stimulation reduces seizure severity but not afterdischarge duration of partial seizures kindled in the hippocampus at threshold intensities , 2005, Neuroscience Letters.

[7]  M. Neale,et al.  Are Smarter Brains Running Faster? Heritability of Alpha Peak Frequency, IQ, and Their Interrelation , 2001, Behavior genetics.

[8]  G. A. Miller,et al.  Spontaneous brain magnetic activity in schizophrenia patients treated with aripiprazole. , 1998, Psychopharmacology bulletin.

[9]  G. Harding,et al.  Clinical Significance of EEG Abnormalities During Photic Stimulation in Patients with Photosensitive Epilepsy , 1999, Epilepsia.

[10]  Franca Tecchio,et al.  Age-Related Changes in Electroencephalographic Signal Complexity , 2015, PloS one.

[11]  I. C. Bruce,et al.  Unilateral low-frequency stimulation of central piriform cortex delays seizure development induced by amygdaloid kindling in rats , 2006, Neuroscience.

[12]  F H Duffy,et al.  Brain electrical activity in patients with presenile and senile dementia of the Alzheimer type , 1984, Annals of neurology.

[13]  S Shinnar,et al.  Practice Parameter: Evaluating an apparent unprovoked first seizure in adults (an evidence-based review): Report of the Quality Standards Subcommittee of the American Academy of Neurology and the American Epilepsy Society , 2007, Neurology.

[14]  Yi Wang,et al.  Low-frequency stimulation in anterior nucleus of thalamus alleviates kainate-induced chronic epilepsy and modulates the hippocampal EEG rhythm , 2016, Experimental Neurology.

[15]  T. Higuchi.  Approach to an irregular time series on the basis of the fractal theory , 1988 .

[16]  John W. Sammon,et al.  A Nonlinear Mapping for Data Structure Analysis , 1969, IEEE Transactions on Computers.

[17]  P. Wong,et al.  Aging and cortical mechanisms of speech perception in noise , 2009, Neuropsychologia.

[18]  A. Tales,et al.  Evoked potentials reveal age-related compensatory mechanisms in early visual processing , 2013, Neurobiology of Aging.

[19]  Yu-Ri Lee,et al.  A Novel EEG Feature Extraction Method Using Hjorth Parameter , 2014 .

[20]  O. Markand.  Electroencephalogram in Dementia , 1986 .

[21]  J. Polich,et al.  EEG and ERP assessment of normal aging. , 1997, Electroencephalography and clinical neurophysiology.

[22]  N. Kazanina,et al.  Auditory perception in the aging brain: the role of inhibition and facilitation in early processing , 2016, Neurobiology of Aging.

[23]  Jeremy B. Caplan,et al.  Distinguishing rhythmic from non-rhythmic brain activity during rest in healthy neurocognitive aging , 2015, NeuroImage.

[24]  I. Kant,et al.  Measurement of prolonged fatigue in the working population: determination of a cutoff point for the checklist individual strength. , 2000, Journal of occupational health psychology.

[25]  C. Kawas,et al.  Abnormal EEGs in Cognitively and Physically Healthy Oldest Old: Findings From The 90+ Study , 2010, Journal of clinical neurophysiology : official publication of the American Electroencephalographic Society.

[26]  Viktor K. Jirsa,et al.  Brain Dynamics of Aging: Multiscale Variability of EEG Signals at Rest and during an Auditory Oddball Task1,2,3 , 2015, eNeuro.

[27]  M. Kikuchi,et al.  Effects of Scopolamine on Interhemispheric EEG Coherence in Healthy Subjects: Analysis during Rest and Photic Stimulation , 2000, Clinical EEG.

[28]  蘆原 郁,et al.  Hearing threshold for pure tones above 20 kHz , 2003 .

[29]  M M Haglund,et al.  Optical imaging of bipolar cortical stimulation. , 1993, Journal of neurosurgery.

[30]  S. Wang,et al.  Unilateral low-frequency stimulation of central piriform cortex inhibits amygdaloid-kindled seizures in Sprague–Dawley rats , 2007, Neuroscience.

[31]  D. E. Shearer,et al.  Power spectral analysis and cortical coupling of EEG for young and old normal adults , 1985, Neurobiology of Aging.

[32]  Mario Christov,et al.  Auditory event-related brain potentials for an early discrimination between normal and pathological brain aging☆ , 2013, Neural regeneration research.

[33]  Richard L Freyman,et al.  Aging and Speech-on-Speech Masking , 2007, Ear and hearing.

[34]  B. Schneider,et al.  Implications of perceptual deterioration for cognitive aging research. , 2000 .

[35]  T. Mizuno,et al.  Age-related variation in EEG complexity to photic stimulation: A multiscale entropy analysis , 2009, Clinical Neurophysiology.

[36]  S. Rossi,et al.  Clinical neurophysiology of aging brain: From normal aging to neurodegeneration , 2007, Progress in Neurobiology.