What we learned about the role of antenatal magnesium sulfate for the prevention of cerebral palsy.

Based on the convincing case control study of Nelson and Grether which suggested that the administration of magnesium sulfate to mothers prior to early preterm birth might protect their offspring from cerebral palsy, and a pilot study by John Hauth et al. at the University of Alabama at Birmingham, the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network, with co-funding from the National Institute of Neurologic Disorders and Stroke embarked on the Beneficial Effects of Antenatal Magnesium (BEAM) Trial in 1997.

[1]  W. H. Pearse,et al.  American College of Obstetricians and Gynecologists , 2018, Definitions.

[2]  R. Farrell,et al.  #3: Periviable birth. , 2015, American journal of obstetrics and gynecology.

[3]  F. Malone,et al.  Antenatal Magnesium and Cerebral Palsy in Preterm Infants. , 2015, The Journal of pediatrics.

[4]  S. Lasocki,et al.  Implementation of an antenatal magnesium sulfate protocol for fetal neuroprotection in preterm infants , 2015, Scientific Reports.

[5]  M. Rice,et al.  Use and attitudes of obstetricians toward 3 high-risk interventions in MFMU Network hospitals. , 2015, American journal of obstetrics and gynecology.

[6]  F. Malone,et al.  Relation between Birth Weight and Weight and Height at the Age of 2 in Children Born Preterm , 2015, American Journal of Perinatology.

[7]  F. Malone,et al.  Effect of Magnesium Sulfate Administration for Neuroprotection on Latency in Women with Preterm Premature Rupture of Membranes , 2014, American Journal of Perinatology.

[8]  F. Malone,et al.  Length of Latency with Preterm Premature Rupture of Membranes before 32 Weeks' Gestation , 2014, American Journal of Perinatology.

[9]  F. Malone,et al.  Association of cord blood digitalis-like factor and necrotizing enterocolitis. , 2014, American journal of obstetrics and gynecology.

[10]  Dwight J Rouse,et al.  The Association of Cord Serum Cytokines with Neurodevelopmental Outcomes , 2009, American Journal of Perinatology.

[11]  D. Rouse,et al.  Evaluation of the Clinical Use of Magnesium Sulfate for Cerebral Palsy Prevention , 2013 .

[12]  F. Malone,et al.  Association of Polymorphisms in Neuroprotection and Oxidative Stress Genes and Neurodevelopmental Outcomes After Preterm Birth , 2012, Obstetrics and gynecology.

[13]  A. Peaceman,et al.  Association of cord blood magnesium concentration and neonatal resuscitation. , 2012, The Journal of pediatrics.

[14]  J. Thorp,et al.  Association of fetal inflammation and coagulation pathway gene polymorphisms with neurodevelopmental delay at age 2 years. , 2010, American journal of obstetrics and gynecology.

[15]  R. Romero,et al.  Antenatal magnesium sulfate for the prevention of cerebral palsy in preterm infants less than 34 weeks' gestation: a systematic review and metaanalysis. , 2009, American journal of obstetrics and gynecology.

[16]  R. Mittendorf,et al.  Magnesium sulfate for the prevention of cerebral palsy. , 2009, The New England journal of medicine.

[17]  F. Malone,et al.  A randomized, controlled trial of magnesium sulfate for the prevention of cerebral palsy. , 2008, The New England journal of medicine.

[18]  L. Doyle,et al.  Magnesium sulphate for women at risk of preterm birth for neuroprotection of the fetus ( Review ) , 2022 .

[19]  Amanda Honeycutt,et al.  Economic costs associated with mental retardation, cerebral palsy, hearing loss, and vision impairment--United States, 2003. , 2004, MMWR. Morbidity and mortality weekly report.

[20]  B. Khoshnood,et al.  Is tocolytic magnesium sulphate associated with increased total paediatric mortality? , 1997, The Lancet.

[21]  M. Morgan,et al.  Evidence for magnesium sulfate as a tocolytic agent. , 1997, Obstetrical & gynecological survey.

[22]  D. Rouse,et al.  The feasibility of a randomized clinical perinatal trial: maternal magnesium sulfate for the prevention of cerebral palsy. , 1996, American journal of obstetrics and gynecology.

[23]  K. Nelson,et al.  Can magnesium sulfate reduce the risk of cerebral palsy in very low birthweight infants? , 1995, Pediatrics.