Lateralized automatic auditory processing of phonetic versus musical information: A PET study

Previous positron emission tomography (PET) and functional magnetic resonance imaging (fMRI) studies show that during attentive listening, processing of phonetic information is associated with higher activity in the left auditory cortex than in the right auditory cortex while the opposite is true for musical information. The present PET study determined whether automatically activated neural mechanisms for phonetic and musical information are lateralized. To this end, subjects engaged in a visual word classification task were presented with phonetic sound sequences consisting of frequent (P = 0.8) and infrequent (P = 0.2) phonemes and with musical sound sequences consisting of frequent (P = 0.8) and infrequent (P = 0.2) chords. The phonemes and chords were matched in spectral complexity as well as in the magnitude of frequency difference between the frequent and infrequent sounds (/e/ vs. /o/; A major vs. A minor). In addition, control sequences, consisting of either frequent (/e/; A major) or infrequent sounds (/o/; A minor) were employed in separate blocks. When sound sequences consisted of intermixed frequent and infrequent sounds, automatic phonetic processing was lateralized to the left hemisphere and musical to the right hemisphere. This lateralization, however, did not occur in control blocks with one type of sound (frequent or infrequent). The data thus indicate that automatic activation of lateralized neuronal circuits requires sound comparison based on short‐term sound representations. Hum. Brain Mapping 10:74–79, 2000. © 2000 Wiley‐Liss, Inc.

[1]  J. Mazziotta,et al.  Tomographic mapping of human cerebral metabolism , 1981, Neurology.

[2]  J. Mazziotta,et al.  Brain Mapping: The Methods , 2002 .

[3]  Paavo Alku,et al.  Glottal wave analysis with Pitch Synchronous Iterative Adaptive Inverse Filtering , 1991, Speech Commun..

[4]  R. Ilmoniemi,et al.  Functional Specialization of the Human Auditory Cortex in Processing Phonetic and Musical Sounds: A Magnetoencephalographic (MEG) Study , 1999, NeuroImage.

[5]  F. Chollet,et al.  Differential fMRI Responses in the Left Posterior Superior Temporal Gyrus and Left Supramarginal Gyrus to Habituation and Change Detection in Syllables and Tones , 1999, NeuroImage.

[6]  M. Tervaniemi,et al.  Development of a memory trace for a complex sound in the human brain. , 1993, Neuroreport.

[7]  M. Torrens.  Co-Planar Stereotaxic Atlas of the Human Brain—3-Dimensional Proportional System: An Approach to Cerebral Imaging, J. Talairach, P. Tournoux. Georg Thieme Verlag, New York (1988), 122 pp., 130 figs. DM 268 , 1990 .

[8]  Alan C. Evans,et al.  Lateralization of phonetic and pitch discrimination in speech processing. , 1992, Science.

[9]  J. Baron,et al.  Topographic EEG activations during timbre and pitch discrimination tasks using musical sounds , 1995, Neuropsychologia.

[10]  Risto Näätänen,et al.  Timbre Similarity: Convergence of Neural, Behavioral, and Computational Approaches , 1998 .

[11]  O Bertrand,et al.  Analysis of speech sounds is left-hemisphere predominant at 100-150ms after sound onset. , 1999, Neuroreport.

[12]  R. Ilmoniemi,et al.  Processing of complex sounds in the human auditory cortex as revealed by magnetic brain responses. , 1996, Psychophysiology.

[13]  C. Wernicke.  Der aphasische Symptomencomplex: Eine psychologische Studie auf anatomischer Basis , 1874 .

[14]  E. Schröger.  On the detection of auditory deviations: a pre-attentive activation model. , 1997, Psychophysiology.

[15]  Risto Näätänen,et al.  Magnetoencephalography in studies of human cognitive brain function , 1994, Trends in Neurosciences.

[16]  Juha Virtanen,et al.  Hemispheric lateralization in preattentive processing of speech sounds , 1998, Neuroscience Letters.

[17]  K. Reinikainen,et al.  Attentive novelty detection in humans is governed by pre-attentive sensory memory , 1994, Nature.

[18]  R Näätänen,et al.  The musical brain: brain waves reveal the neurophysiological basis of musicality in human subjects , 1997, Neuroscience Letters.

[19]  I. Peretz,et al.  Left ear advantage in pitch perception of complex tones without energy at the fundamental frequency , 1996, Neuropsychologia.

[20]  Risto N t nen.  Attention and brain function , 1992 .

[21]  M. Mintun,et al.  A Noninvasive Approach to Quantitative Functional Brain Mapping with H215O and Positron Emission Tomography , 1984, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.

[22]  Paavo Alku,et al.  Background acoustic noise and the hemispheric lateralization of speech processing in the human brain: magnetic mismatch negativity study , 1998, Neuroscience Letters.

[23]  R. Ilmoniemi,et al.  Language-specific phoneme representations revealed by electric and magnetic brain responses , 1997, Nature.

[24]  R. Ilmoniemi,et al.  Magnetoencephalography-theory, instrumentation, and applications to noninvasive studies of the working human brain , 1993 .

[25]  A. Friederici,et al.  Noise affects auditory and linguistic processing differently: an MEG study , 2000, Neuroreport.

[26]  A Jesmanowicz,et al.  Lateralized human brain language systems demonstrated by task subtraction functional magnetic resonance imaging. , 1995, Archives of neurology.

[27]  P. T. Fox,et al.  Positron emission tomographic studies of the cortical anatomy of single-word processing , 1988, Nature.

[28]  D. V. von Cramon,et al.  Combining electrophysiological and hemodynamic measures of the auditory oddball. , 1999, Psychophysiology.

[29]  A. Syrota,et al.  The Cortical Representation of Speech , 1993, Journal of Cognitive Neuroscience.

[30]  K. Alho.  Cerebral Generators of Mismatch Negativity (MMN) and Its Magnetic Counterpart (MMNm) Elicited by Sound Changes , 1995, Ear and hearing.

[31]  J. Tichy,et al.  Amusia , 1894, British medical journal.