Mems and Neurosurgery

Neurosurgery is the branch of medicine that concerns itself with the diagnosis and surgical treatment of disorders affecting the nervous system, both centrally and peripherally. The central nervous system consists of the brain and spinal cord (Figure 6.1). It is not capable of full regeneration after injury, which is in striking contrast to the peripheral nervous system. The brain and spinal cord are the higher processing centers that regulate and control the peripheral nervous system. The latter is directly responsible for movement, speech, and action. Thus, it is the neurosurgeon’s charge to restore and preserve these functions. The neurosurgeon surgically tackles such entities as head trauma, brain injuries, spinal cord injuries, degenerative spine disease, aneurysms, tumors, and congenital malformations of the brain, skull, and spine.

[1]  Neurosurgery for Parkinson's disease. , 2001, Seminars in neurology.

[2]  M Ferrari,et al.  Microfabricated immunoisolating biocapsules. , 1998, Biotechnology and bioengineering.

[3]  J. Goodrich History of spine surgery in the ancient and medieval worlds. , 2004, Neurosurgical focus.

[4]  M. A. Johnson,et al.  Chronic recording of regenerating VIIIth nerve axons with a sieve electrode. , 2000, Journal of neurophysiology.

[5]  R. Drucker-Colín,et al.  Cell Transplantation for Parkinson's Disease: Present Status , 2004, Cellular and Molecular Neurobiology.

[6]  Henry Brem,et al.  Recent Advances in Brain Tumor Therapy: Local Intracerebral Drug Delivery by Polymers , 2004, Investigational New Drugs.

[7]  Henry Helvajian,et al.  Microengineering aerospace systems , 1999 .

[8]  M. Kaps,et al.  Feasibility and validity of transcranial duplex sonography in patients with acute stroke , 2002, Journal of neurology, neurosurgery, and psychiatry.

[9]  K. Najafi,et al.  Solid-state microsensors for cortical nerve recordings , 1994, IEEE Engineering in Medicine and Biology Magazine.

[10]  G. Martin Was Hippocrates a beginner at trepanning and where did he learn? , 2000, Journal of Clinical Neuroscience.

[11]  E. Montgomery Two advances in the management of Parkinson disease. , 2002, Cleveland Clinic journal of medicine.

[12]  E. Rossitch,et al.  The history of trephination in Africa with a discussion of its current status and continuing practice. , 1994, Surgical neurology.

[13]  Y. Tai,et al.  The neurochip: a new multielectrode device for stimulating and recording from cultured neurons , 1999, Journal of Neuroscience Methods.

[14]  Shuvo Roy,et al.  Miniature high frequency focused ultrasonic transducers for minimally invasive imaging procedures , 2003 .

[15]  M. Apuzzo,et al.  The Genesis of Neurosurgery and the Evolution of the Neurosurgical Operative Environment: Part II—Concepts for Future Development, 2003 and Beyond , 2003, Neurosurgery.

[16]  D. Groothuis,et al.  The blood-brain and blood-tumor barriers: a review of strategies for increasing drug delivery. , 2000, Neuro-oncology.

[17]  Rutkow Im Moments in surgical history. Trephination: how did they do it? , 2000 .

[18]  O. Lindvall,et al.  Stem cell therapy for human neurodegenerative disorders–how to make it work , 2004, Nature Medicine.

[19]  K. Wise,et al.  A high-yield IC-compatible multichannel recording array , 1985, IEEE Transactions on Electron Devices.

[20]  S. E. Gindi,et al.  Neurosurgery in Egypt: past, present, and future-from pyramids to radiosurgery. , 2002 .

[21]  W. Kohnen,et al.  Development of a long-lasting ventricular catheter impregnated with a combination of antibiotics. , 2003, Biomaterials.

[22]  D. Sakas,et al.  Hydrocephalus According to Byzantine Writers , 2004, Neurosurgery.

[23]  J. Drake,et al.  The shunt book , 1995 .

[24]  G. Kotzar,et al.  Evaluation of MEMS materials of construction for implantable medical devices. , 2002, Biomaterials.

[25]  James M. Bower,et al.  Plasma-etched neural probes , 1996 .

[26]  B. Brinkmann,et al.  Arrow Wounds: Major Stimulus in the History of Surgery , 2001, World Journal of Surgery.

[27]  Shuvo Roy,et al.  An in vivo Biocompatibility Assessment of MEMS Materials for Spinal Fusion Monitoring , 2003 .

[28]  I. Pople,et al.  HYDROCEPHALUS AND SHUNTS: WHAT THE NEUROLOGIST SHOULD KNOW , 2002, Journal of neurology, neurosurgery, and psychiatry.

[29]  A. Fleischman,et al.  Silicon dermabrasion tools for skin resurfacing applications. , 2003, Medical engineering & physics.

[30]  E. Laws,et al.  Neurosurgery's man of the century: Harvey Cushing--the man and his legacy. , 1999, Neurosurgery.

[31]  Jung Kyung Kim,et al.  Development of MEMS-based Cerebrospinal Fluid Shunt System , 2003 .

[32]  Haas Lf Papyrus of Ebers and Smith. , 1999 .

[33]  D. Campillo Neurosurgical pathology in prehistory , 2005, Acta Neurochirurgica.

[34]  D L Polla,et al.  Microdevices in medicine. , 2000, Annual review of biomedical engineering.

[35]  A. Fleischman,et al.  Microelectromechanical Systems and Neurosurgery: A New Era in a New Millennium , 2001, Neurosurgery.

[36]  Richard D. Guyer,et al.  Intervertebral Disc Prostheses , 2003, Spine.

[37]  A. Fleischman,et al.  Micromachines in Spine Surgery , 2004, Spine.

[38]  Shuvo Roy,et al.  Cytotoxicity Evaluation of Microsystems Materials Using Human Cells , 2003 .

[39]  D. McDonnell,et al.  History of spinal surgery: one neurosurgeon's perspective. , 2004, Neurosurgical focus.

[40]  J. Stone Paul Broca and the first craniotomy based on cerebral localization. , 1991, Journal of neurosurgery.

[41]  P H Peckham,et al.  At the interface: convergence of neural regeneration and neural prostheses for restoration of function. , 2001, Journal of rehabilitation research and development.

[42]  David J. Edell,et al.  A Peripheral Nerve Information Transducer for Amputees: Long-Term Multichannel Recordings from Rabbit Peripheral Nerves , 1986, IEEE Transactions on Biomedical Engineering.

[43]  P. Black,et al.  Harvey Cushing at the Peter Bent Brigham Hospital. , 1999, Neurosurgery.

[44]  M. Allen,et al.  Microfabricated microneedles for gene and drug delivery. , 2000, Annual review of biomedical engineering.

[45]  M. Apuzzo,et al.  The Genesis of Neurosurgery and the Evolution of the Neurosurgical Operative Environment: Part I—Prehistory to 2003 , 2003, Neurosurgery.

[46]  E. Benzel Biomechanics of Spine Stabilization , 1994 .

[47]  Roger Bayston,et al.  Mode of action of an antimicrobial biomaterial for use in hydrocephalus shunts. , 2004, The Journal of antimicrobial chemotherapy.

[49]  J. Hetke,et al.  Strength characterization of silicon microprobes in neurophysiological tissues , 1990, IEEE Transactions on Biomedical Engineering.

[50]  W. Ko,et al.  Intracranial Pressure Telemetry System Using Semicustom Integrated Circuits , 1986, IEEE Transactions on Biomedical Engineering.

[51]  Jiping He,et al.  Polyimide-based intracortical neural implant with improved structural stiffness , 2004 .

[52]  B. Schlosshauer,et al.  Towards micro electrode implants: in vitro guidance of rat spinal cord neurites through polyimide sieves by Schwann cells , 2001, Brain Research.

[53]  U. von Smekal,et al.  Stone age skull surgery in Mecklenburg-Vorpommern: a systematic study. , 1999, Neurosurgery.

[54]  J. Drake,et al.  CSF shunts 50 years on – past, present and future , 2000, Child's Nervous System.

[55]  S. Greenblatt The crucial decade: modern neurosurgery's definitive development in Harvey Cushing's early research and practice, 1900 to 1910. , 1997, Journal of neurosurgery.

[56]  G. Kovacs,et al.  Regeneration microelectrode array for peripheral nerve recording and stimulation , 1992, IEEE Transactions on Biomedical Engineering.

[57]  Wen H. Ko,et al.  Cerebrospinal fluid control system , 1988 .

[58]  R. Penn,et al.  Long-term testing of an intracranial pressure monitoring device. , 2000, Journal of neurosurgery.

[59]  D. Edell,et al.  Factors influencing the biocompatibility of insertable silicon microshafts in cerebral cortex , 1992, IEEE Transactions on Biomedical Engineering.

[60]  Justin C. Williams,et al.  Flexible polyimide-based intracortical electrode arrays with bioactive capability , 2001, IEEE Transactions on Biomedical Engineering.

[61]  Peter S. Donzelli,et al.  Real-Time In Vivo Loading in the Lumbar Spine: Part 1. Interbody Implant: Load Cell Design and Preliminary Results , 2000, Spine.