Discovery of the First Potent Inhibitors of Mutant IDH1 That Lower Tumor 2-HG in Vivo.
暂无分享,去创建一个
S. Gross | Shunqi Yan | J. Saunders | K. Kunii | Hua Yang | K. Yen | S. Su | Shengfang Jin | F. Salituro | L. Dang | V. Fantin | K. Straley | Shinsan M. Su | Janeta Popovici-Muller | S. Biller | J. Travins | Shunan Zhang | Qiongqun Pan | Fang Zhao | Derek Shi
[1] G. Reifenberger,et al. IDH1(R132H) mutation increases murine haematopoietic progenitors and alters epigenetics , 2012, Nature.
[2] A. Viale,et al. IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype , 2012, Nature.
[3] S. Berger,et al. IDH mutation impairs histone demethylation and results in a block to cell differentiation , 2012, Nature.
[4] A. Grigoriadis,et al. IDH1 and IDH2 mutations are frequent events in central chondrosarcoma and central and periosteal chondromas but not in other mesenchymal tumours , 2011, The Journal of pathology.
[5] R. Klose,et al. The oncometabolite 2‐hydroxyglutarate inhibits histone lysine demethylases , 2011, EMBO reports.
[6] Bin Wang,et al. Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases. , 2011, Cancer cell.
[7] K. Yen,et al. Cancer-associated IDH mutations: biomarker and therapeutic opportunities , 2010, Oncogene.
[8] Manuela Zucknick,et al. IDH1 and IDH2 mutations are frequent genetic alterations in acute myeloid leukemia and confer adverse prognosis in cytogenetically normal acute myeloid leukemia with NPM1 mutation without FLT3 internal tandem duplication. , 2010, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[9] Hai Yan,et al. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. , 2010, Journal of the National Cancer Institute.
[10] L. Liau,et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate , 2010, Nature.
[11] Bing Yang,et al. Preparation, Physicochemical Properties, and Hemocompatibility of the Composites Based on Biodegradable Poly(Ether-Ester-Urethane) and Phosphorylcholine-Containing Copolymer , 2019, Polymers.
[12] R. McLendon,et al. IDH1 and IDH2 mutations in gliomas. , 2009, The New England journal of medicine.
[13] L. Liau,et al. Cancer-associated IDH1 mutations produce 2-hydroxyglutarate , 2009, Nature.
[14] Christian Mawrin,et al. Type and frequency of IDH1 and IDH2 mutations are related to astrocytic and oligodendroglial differentiation and age: a study of 1,010 diffuse gliomas , 2009, Acta Neuropathologica.
[15] J. Uhm. An Integrated Genomic Analysis of Human Glioblastoma Multiforme , 2009 .
[16] I. Ugi,et al. The Passerini and Ugi Reactions , 1991 .