Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo
暂无分享,去创建一个
[1] W. Muller,et al. Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo , 2012, Breast Cancer Research.
[2] W. Muller,et al. Mammary epithelial-specific disruption of c-Src impairs cell cycle progression and tumorigenesis , 2011, Proceedings of the National Academy of Sciences.
[3] J. Guan,et al. Compensatory Function of Pyk2 Protein in the Promotion of Focal Adhesion Kinase (FAK)-null Mammary Cancer Stem Cell Tumorigenicity and Metastatic Activity* , 2011, The Journal of Biological Chemistry.
[4] G. Forni,et al. p130Cas is an essential transducer element in ErbB2 transformation , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[5] W. Muller,et al. β1-integrin is dispensable for the induction of ErbB2 mammary tumors but plays a critical role in the metastatic phase of tumor progression , 2010, Proceedings of the National Academy of Sciences.
[6] G. Mills,et al. Integrin-linked kinase has a critical role in ErbB2 mammary tumor progression: implications for human breast cancer , 2010, Oncogene.
[7] G. Mcmahon,et al. Oral delivery of PND-1186 FAK inhibitor decreases tumor growth and spontaneous breast to lung metastasis in pre-clinical models , 2010, Cancer biology & therapy.
[8] G. Mcmahon,et al. PND-1186 FAK inhibitor selectively promotes tumor cell apoptosis in three-dimensional environments , 2010, Cancer biology & therapy.
[9] H. Frierson,et al. Differential requirement for focal adhesion kinase signaling in cancer progression in the transgenic adenocarcinoma of mouse prostate model , 2009, Molecular Cancer Therapeutics.
[10] W. Gerald,et al. Ras- and PI3K-dependent breast tumorigenesis in mice and humans requires focal adhesion kinase signaling. , 2009, The Journal of clinical investigation.
[11] M. Wicha,et al. Mammary epithelial-specific ablation of the focal adhesion kinase suppresses mammary tumorigenesis by affecting mammary cancer stem/progenitor cells. , 2009, Cancer research.
[12] Paolo P. Provenzano,et al. Tumorigenesis and Neoplastic Progression Mammary Epithelial-Specific Disruption of Focal Adhesion Kinase Retards Tumor Formation and Metastasis in a Transgenic Mouse Model of Human Breast Cancer , 2008 .
[13] T. Bismar,et al. Tumorigenesis and Neoplastic Progression Focal Adhesion Kinase-Related Proline-Rich Tyrosine Kinase 2 and Focal Adhesion Kinase Are Co-Overexpressed in Early-Stage and Invasive ErbB2-Positive Breast Cancer and Cooperate for Breast Cancer Cell Tumorigenesis and Invasiveness , 2010 .
[14] D. Haber,et al. Modeling oncogene addiction using RNA interference , 2008, Proceedings of the National Academy of Sciences.
[15] J. Guan,et al. Compensatory role for Pyk2 during angiogenesis in adult mice lacking endothelial cell FAK , 2008, The Journal of cell biology.
[16] T. Pawson,et al. ShcA signalling is essential for tumour progression in mouse models of human breast cancer , 2008, The EMBO journal.
[17] Matthew D. Wessel,et al. Antitumor activity and pharmacology of a selective focal adhesion kinase inhibitor, PF-562,271. , 2008, Cancer research.
[18] R. Cardiff,et al. Mammary epithelial-specific disruption of the focal adhesion kinase blocks mammary tumor progression , 2007, Proceedings of the National Academy of Sciences.
[19] D. Schlaepfer,et al. FAK signaling is critical for ErbB-2/ErbB-3 receptor cooperation for oncogenic transformation and invasion , 2005, The Journal of cell biology.
[20] Joseph Geradts,et al. High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype , 2005, Modern Pathology.
[21] R. Kimmig,et al. High expression of focal adhesion kinase (p125FAK) in node-negative breast cancer is related to overexpression of HER-2/neu and activated Akt kinase but does not predict outcome , 2005, Breast Cancer Research.
[22] S. Grant,et al. Specific deletion of focal adhesion kinase suppresses tumor formation and blocks malignant progression. , 2004, Genes & development.
[23] C. Livasy,et al. Upregulation of focal adhesion kinase (FAK) expression in ductal carcinoma in situ (DCIS) is an early event in breast tumorigenesis , 2004, Breast Cancer Research and Treatment.
[24] W. Muller,et al. Targeted disruption of beta1-integrin in a transgenic mouse model of human breast cancer reveals an essential role in mammary tumor induction. , 2004, Cancer cell.
[25] G. Nemerow,et al. Differential regulation of cell motility and invasion by FAK , 2003, The Journal of cell biology.
[26] L. Koss,et al. Focal adhesion kinase as a marker of malignant phenotype in breast and cervical carcinomas. , 2003, Human pathology.
[27] E. Ruoslahti,et al. Decreased focal adhesion kinase suppresses papilloma formation during experimental mouse skin carcinogenesis. , 2001, Cancer research.
[28] D. Brenner,et al. The Focal Adhesion Kinase Suppresses Transformation-associated, Anchorage-independent Apoptosis in Human Breast Cancer Cells , 2000, The Journal of Biological Chemistry.
[29] C. Smart,et al. The Proliferative and Migratory Activities of Breast Cancer Cells Can Be Differentially Regulated by Heparan Sulfates* , 2000, The Journal of Biological Chemistry.
[30] M. Rudnicki,et al. Amplification of the neu/erbB-2 oncogene in a mouse model of mammary tumorigenesis. , 2000, Proceedings of the National Academy of Sciences of the United States of America.
[31] S. Ethier,et al. ERBB-2 overexpression confers PI 3 ′ kinase-dependent invasion capacity on human mammary epithelial cells , 2000, British Journal of Cancer.
[32] R. Cardiff,et al. Elevated expression of activated forms of Neu/ErbB‐2 and ErbB‐3 are involved in the induction of mammary tumors in transgenic mice: implications for human breast cancer , 1999, The EMBO journal.
[33] Philippe Soriano. Generalized lacZ expression with the ROSA26 Cre reporter strain , 1999, Nature Genetics.