Ectopic calcification in pseudoxanthoma elasticum responds to inhibition of tissue-nonspecific alkaline phosphatase
暂无分享,去创建一个
E. Chew | H. Dietz | W. Gahl | C. Ferreira | J. Millán | E. Sergienko | R. Tomlinson | A. Pinkerton | S. G. Ziegler | Chen-Ting Ma | Ludovic Martin | Ryan C. Riddle | R. Riddle | E. MacFarlane
[1] J. Millán,et al. Transgenic Overexpression of Tissue‐Nonspecific Alkaline Phosphatase (TNAP) in Vascular Endothelium Results in Generalized Arterial Calcification , 2015, Journal of the American Heart Association.
[2] J. Millán,et al. Alkaline Phosphatase and Hypophosphatasia , 2015, Calcified Tissue International.
[3] J. Millán,et al. Effects of etidronate on the Enpp1−/− mouse model of generalized arterial calcification of infancy , 2015, International journal of molecular medicine.
[4] J. Millán,et al. Pathophysiological Role of Vascular Smooth Muscle Alkaline Phosphatase in Medial Artery Calcification , 2015, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[5] S. Schulte-Merker,et al. Vitamin K reduces hypermineralisation in zebrafish models of PXE and GACI , 2015, Development.
[6] S. Terry,et al. The effects of bisphosphonates on ectopic soft tissue mineralization caused by mutations in the ABCC6 gene , 2015, Cell cycle.
[7] G. Gerosa,et al. Extracellular pyrophosphate is reduced in aortic interstitial valve cells acquiring a calcifying profile: implications for aortic valve calcification. , 2014, Atherosclerosis.
[8] P. Borst,et al. ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report , 2014, Arteriosclerosis, thrombosis, and vascular biology.
[9] C. Götting,et al. Pyrophosphates as a major inhibitor of matrix calcification in Pseudoxanthoma elasticum. , 2014, Journal of dermatological science.
[10] A. Yoganathan,et al. The role of inorganic pyrophosphate in aortic valve calcification. , 2014, The Journal of heart valve disease.
[11] B. Ponsioen,et al. Zebrafish enpp1 mutants exhibit pathological mineralization, mimicking features of generalized arterial calcification of infancy (GACI) and pseudoxanthoma elasticum (PXE) , 2014, Disease Models & Mechanisms.
[12] P. Borst,et al. ABCC6 prevents ectopic mineralization seen in pseudoxanthoma elasticum by inducing cellular nucleotide release , 2013, Proceedings of the National Academy of Sciences.
[13] G. Szakács,et al. ABCC6 Is a Basolateral Plasma Membrane Protein , 2013, Circulation research.
[14] R. Tiozzo,et al. Matrix gla protein and alkaline phosphatase are differently modulated in human dermal fibroblasts from PXE patients and controls. , 2013, The Journal of investigative dermatology.
[15] J. Millán,et al. Severe skeletal toxicity from protracted etidronate therapy for generalized arterial calcification of infancy , 2013, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[16] J. Sundberg,et al. A single nucleotide polymorphism in the Abcc6 gene associates with connective tissue mineralization in mice similar to targeted models for pseudoxanthoma elasticum , 2012, The Journal of investigative dermatology.
[17] E. Sergienko,et al. A method for direct assessment of tissue-nonspecific alkaline phosphatase (TNAP) inhibitors in blood samples. , 2013, Methods in molecular biology.
[18] G. Leftheriotis,et al. Quantification of the calcification phenotype of Abcc6-deficient mice with microcomputed tomography. , 2012, The American journal of pathology.
[19] M. McCulloch,et al. Generalized arterial calcification of infancy and pseudoxanthoma elasticum can be caused by mutations in either ENPP1 or ABCC6. , 2012, American journal of human genetics.
[20] T. Markello,et al. NT5E mutations and arterial calcifications. , 2011, The New England journal of medicine.
[21] M. Zylka,et al. NT5E mutations and arterial calcifications. , 2011, The New England journal of medicine.
[22] M. Zylka,et al. NT5E mutations and arterial calcifications. , 2011, The New England journal of medicine.
[23] Ralph Müller,et al. Guidelines for assessment of bone microstructure in rodents using micro–computed tomography , 2010, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[24] J. Uitto,et al. Parabiotic heterogenetic pairing of Abcc6-/-/Rag1-/- mice and their wild-type counterparts halts ectopic mineralization in a murine model of pseudoxanthoma elasticum. , 2010, The American journal of pathology.
[25] W. C. O'Neill,et al. Plasma pyrophosphate and vascular calcification in chronic kidney disease. , 2010, Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association.
[26] Brock T Brown,et al. Discovery and validation of a series of aryl sulfonamides as selective inhibitors of tissue-nonspecific alkaline phosphatase (TNAP). , 2009, Journal of medicinal chemistry.
[27] J. Uitto,et al. Pseudoxanthoma elasticum is a metabolic disease. , 2009, The Journal of investigative dermatology.
[28] B. Clarke,et al. Bisphosphonates: mechanism of action and role in clinical practice. , 2008, Mayo Clinic proceedings.
[29] J. Millán,et al. Novel Inhibitors of Alkaline Phosphatase Suppress Vascular Smooth Muscle Cell Calcification , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[30] L. Schurgers,et al. Matrix Gla protein is involved in elastic fiber calcification in the dermis of pseudoxanthoma elasticum patients , 2007, Laboratory Investigation.
[31] Mary L Bouxsein,et al. Age‐Related Changes in Trabecular Architecture Differ in Female and Male C57BL/6J Mice , 2007, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[32] M. Bouxsein,et al. Age-Related Changes in Trabecular Architecture Differ in Female and Male C 57 BL / 6 J Mice * , 2007 .
[33] J. Uitto,et al. Pseudoxanthoma elasticum: a metabolic disease? , 2006, The Journal of investigative dermatology.
[34] V. Douet,et al. Serum factors from pseudoxanthoma elasticum patients alter elastic fiber formation in vitro. , 2006, The Journal of investigative dermatology.
[35] H. Fleisch,et al. Effect of ethane-1-hydroxy-1,1-diphosphonate (EHDP) and dichloromethylene diphosphonate (Cl2MDP) on the calcification and resorption of cartilage and bone in the tibial epiphysis and metaphysis of rats , 1973, Calcified Tissue Research.
[36] J. Uitto,et al. Tissue-specific expression of the ABCC6 gene. , 2005, The Journal of investigative dermatology.
[37] J. Sundberg,et al. Targeted Ablation of the Abcc6 Gene Results in Ectopic Mineralization of Connective Tissues , 2005, Molecular and Cellular Biology.
[38] W. C. O'Neill,et al. Reduced plasma pyrophosphate levels in hemodialysis patients. , 2005, Journal of the American Society of Nephrology : JASN.
[39] W. C. O'Neill,et al. Phosphate-induced vascular calcification: role of pyrophosphate and osteopontin. , 2004, Journal of the American Society of Nephrology : JASN.
[40] R. Terkeltaub,et al. Concerted regulation of inorganic pyrophosphate and osteopontin by akp2, enpp1, and ank: an integrated model of the pathogenesis of mineralization disorders. , 2004, The American journal of pathology.
[41] R. Terkeltaub,et al. Mutations in ENPP1 are associated with 'idiopathic' infantile arterial calcification , 2003, Nature Genetics.
[42] B. Sarkadi,et al. Loss of ATP-dependent Transport Activity in Pseudoxanthoma Elasticum-associated Mutants of Human ABCC6 (MRP6)* , 2002, The Journal of Biological Chemistry.
[43] R. Terkeltaub. Inorganic pyrophosphate generation and disposition in pathophysiology. , 2001, American journal of physiology. Cell physiology.
[44] P. Price,et al. Bisphosphonates Alendronate and Ibandronate Inhibit Artery Calcification at Doses Comparable to Those That Inhibit Bone Resorption , 2001, Arteriosclerosis, thrombosis, and vascular biology.
[45] P. Schauerte,et al. Low levels of urinary inorganic pyrophosphate indicating systemic pyrophosphate deficiency in a boy with idiopathic infantile arterial calcification , 2000, Acta paediatrica.
[46] R. Terkeltaub,et al. Mitochondrial oxidative phosphorylation is a downstream regulator of nitric oxide effects on chondrocyte matrix synthesis and mineralization. , 2000, Arthritis and rheumatism.
[47] Jerilyn A. Walker,et al. Preparation of PCR-quality mouse genomic DNA with hot sodium hydroxide and tris (HotSHOT). , 2000, BioTechniques.
[48] M. Kool,et al. Mutations in ABCC6 cause pseudoxanthoma elasticum , 2000, Nature Genetics.
[49] S. Terry,et al. Mutations in a gene encoding an ABC transporter cause pseudoxanthoma elasticum , 2000, Nature Genetics.
[50] R. Tiozzo,et al. Abnormal phenotype of in vitro dermal fibroblasts from patients with Pseudoxanthoma elasticum (PXE). , 2000, Biochimica et biophysica acta.
[51] R. Terkeltaub,et al. Differential mechanisms of inorganic pyrophosphate production by plasma cell membrane glycoprotein-1 and B10 in chondrocytes. , 1999, Arthritis and rheumatism.
[52] A. Stuart. Idiopathic arterial calcification of infancy and pyrophosphate deficiency. , 1993, The Journal of pediatrics.
[53] G. De Luca,et al. Pseudoxanthoma elasticum (PXE): ultrastructural and biochemical study on proteoglycan and proteoglycan-associated material produced by skin fibroblasts in vitro. , 1988, Collagen and related research.
[54] D. Leys,et al. Generalized Arterial Calcification of Infancy , 1957, British medical journal.