Protective effects of alogliptin against TNF‐&agr;‐induced degradation of extracellular matrix in human chondrocytes

[1]  Bríain ó. Hartaigh Serum , 2019, Encyclopedia of Behavioral Medicine.

[2]  Guoqing Li,et al.  Protective effects of gemigliptin against type II collagen degradation in human chondrocytes. , 2018, Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie.

[3]  G. Hofmann,et al.  Human osteochondritis dissecans fragment-derived chondrocyte characteristics ex vivo, after monolayer expansion-induced de-differentiation, and after re-differentiation in alginate bead culture , 2018, BMC Musculoskeletal Disorders.

[4]  B. Moradi,et al.  M1/M2 macrophages induce chondral MMP/ADAMTS enzyme secretion in a direct co-culture experiment , 2018 .

[5]  C. Schönfeld,et al.  Novel Insights into the Pathogenesis of Osteoarthritis. , 2017, Current rheumatology reviews.

[6]  A. Filiberti,et al.  Immune Contributions to Osteoarthritis , 2017, Current Osteoporosis Reports.

[7]  Lin Wang,et al.  Estradiol and proinflammatory cytokines stimulate ISG20 expression in synovial fibroblasts of patients with osteoarthritis. , 2017, Intractable & rare diseases research.

[8]  Yoshio Kobayashi,et al.  DPP-4 inhibition protects human umbilical vein endothelial cells from hypoxia-induced vascular barrier impairment. , 2017, Journal of pharmacological sciences.

[9]  Xiao-zhou Ying,et al.  Silibinin protects against osteoarthritis through inhibiting the inflammatory response and cartilage matrix degradation in vitro and in vivo , 2017, Oncotarget.

[10]  B. Poulet Models to define the stages of articular cartilage degradation in osteoarthritis development , 2017, International journal of experimental pathology.

[11]  Hyun Jae Lee,et al.  Effect of oleanolic acid on the activity, secretion and gene expression of matrix metalloproteinase-3 in articular chondrocytes in vitro and the production of matrix metalloproteinase-3 in vivo , 2017, The Korean journal of physiology & pharmacology : official journal of the Korean Physiological Society and the Korean Society of Pharmacology.

[12]  Wenhao Zheng,et al.  Butein inhibits IL‐1&bgr;‐induced inflammatory response in human osteoarthritis chondrocytes and slows the progression of osteoarthritis in mice , 2017, International immunopharmacology.

[13]  S. Kaneko,et al.  DPP-4 Inhibition by Linagliptin Attenuates Obesity-Related Inflammation and Insulin Resistance by Regulating M1/M2 Macrophage Polarization , 2016, Diabetes.

[14]  M. Chopra,et al.  Pharmacophore development and screening for discovery of potential inhibitors of ADAMTS-4 for osteoarthritis therapy , 2016, Journal of Molecular Modeling.

[15]  K. Staines,et al.  New developments in osteoarthritis and cartilage biology. , 2016, Current opinion in pharmacology.

[16]  D. Yabe,et al.  Alogliptin for the treatment of type 2 diabetes: a drug safety evaluation , 2016, Expert opinion on drug safety.

[17]  Dean M. Messing,et al.  Discovery of N-(4-Fluoro-3-methoxybenzyl)-6-(2-(((2S,5R)-5-(hydroxymethyl)-1,4-dioxan-2-yl)methyl)-2H-tetrazol-5-yl)-2-methylpyrimidine-4-carboxamide. A Highly Selective and Orally Bioavailable Matrix Metalloproteinase-13 Inhibitor for the Potential Treatment of Osteoarthritis. , 2016, Journal of medicinal chemistry.

[18]  J. Saklatvala,et al.  Brief Report: JNK‐2 Controls Aggrecan Degradation in Murine Articular Cartilage and the Development of Experimental Osteoarthritis , 2015, Arthritis & rheumatology.

[19]  Zhongyi Sun,et al.  IL-1β promotes ADAMTS enzyme-mediated aggrecan degradation through NF-κB in human intervertebral disc , 2015, Journal of Orthopaedic Surgery and Research.

[20]  K. Uchida,et al.  CD11c+ macrophages and levels of TNF‐α and MMP‐3 are increased in synovial and adipose tissues of osteoarthritic mice with hyperlipidaemia , 2015, Clinical and experimental immunology.

[21]  C. Malemud Biologic basis of osteoarthritis: state of the evidence , 2015, Current opinion in rheumatology.

[22]  R. Trawick,et al.  Serum cytokines are increased and circulating micronutrients are not altered in subjects with early compared to advanced knee osteoarthritis. , 2014, Cytokine.

[23]  S. Miyamoto,et al.  Dipeptidyl peptidase-4 inhibitor ameliorates early renal injury through its anti-inflammatory action in a rat model of type 1 diabetes. , 2014, Biochemical and biophysical research communications.

[24]  N. Sugano,et al.  Synovial joint fluid cytokine levels in hip disease. , 2014, Rheumatology.

[25]  Krishna Dalal,et al.  ADAMTS‐4 and ADAMTS‐5: Key enzymes in osteoarthritis , 2011, Journal of cellular biochemistry.

[26]  M. Goldring,et al.  Inflammation in osteoarthritis , 2011, Current opinion in rheumatology.

[27]  Wan‐Lin Wu,et al.  Advanced glycation end products cause collagen II reduction by activating Janus kinase/signal transducer and activator of transcription 3 pathway in porcine chondrocytes. , 2011, Rheumatology.

[28]  Joshua J. Neumiller Differential chemistry (structure), mechanism of action, and pharmacology of GLP-1 receptor agonists and DPP-4 inhibitors. , 2009, Journal of the American Pharmacists Association : JAPhA.

[29]  B. Bresnihan,et al.  Human rheumatoid arthritis tissue production of IL-17A drives matrix and cartilage degradation: synergy with tumour necrosis factor-α, Oncostatin M and response to biologic therapies , 2009, Arthritis research & therapy.

[30]  S. Jimenez,et al.  NF-κB as a potential therapeutic target in osteoarthritis and rheumatoid arthritis , 2006 .

[31]  L. Duong,et al.  The role of subchondral bone remodeling in osteoarthritis: reduction of cartilage degeneration and prevention of osteophyte formation by alendronate in the rat anterior cruciate ligament transection model. , 2004, Arthritis and rheumatism.

[32]  C. Brinckerhoff,et al.  Interleukin-1 induction of collagenase 3 (matrix metalloproteinase 13) gene expression in chondrocytes requires p38, c-Jun N-terminal kinase, and nuclear factor kappaB: differential regulation of collagenase 1 and collagenase 3. , 2000, Arthritis and rheumatism.

[33]  A. Baker,et al.  Nuclear factor kappaB activity is essential for matrix metalloproteinase-1 and -3 upregulation in rabbit dermal fibroblasts. , 1999, Biochemical and biophysical research communications.

[34]  E. Zandi,et al.  The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.