Minimally invasive proximal interphalangeal joint arthrodesis using a locking compression plate and tissue engineering in horses: a pilot study.

This pilot study assessed the efficacy of 2 minimally invasive techniques for proximal interphalangeal (PIP) joint arthrodesis in horses. The PIP joints of both forelimbs (n = 6) were stabilized with locking compression plates (LCP) using a minimally invasive technique (LCP technique). Subsequently, for 1 randomly selected PIP joint of each horse, surgical drilling (SurD) was performed and tissue engineering (TE) was applied (LCP/SurD/TE technique). Minimally invasive PIP joint arthrodesis with LCP demonstrated low postoperative infection rates. Gross and histological evaluations revealed considerable destruction of the articular cartilage in the LCP/SurD/TE-treated joints. In contrast, almost no destruction of the cartilage was observed in the LCP-treated joints. Our results suggest that the LCP technique alone is not sufficient for PIP joint arthrodesis and that the LCP/SurD/TE technique may be useful for PIP joint arthrodesis in horses.

[1]  Y. Tabata,et al.  In vivo osteoinductivity of gelatin β-tri-calcium phosphate sponge and bone morphogenetic protein-2 on an equine third metacarpal bone defect. , 2012, Research in veterinary science.

[2]  L. Panizzi,et al.  Evaluation of a minimally invasive arthrodesis technique for the carpometacarpal joint in horses. , 2011, Veterinary surgery : VS.

[3]  J. Carmalt,et al.  Evaluation of ethyl alcohol for use in a minimally invasive technique for equine proximal interphalangeal joint arthrodesis. , 2011, Veterinary surgery : VS.

[4]  R. Boston,et al.  Orthopedic infections in equine long bone fractures and arthrodeses treated by internal fixation: 192 cases (1990-2006). , 2010, Veterinary surgery : VS.

[5]  L. Berg,et al.  Current and future regenerative medicine - principles, concepts, and therapeutic use of stem cell therapy and tissue engineering in equine medicine. , 2009, The Canadian veterinary journal = La revue veterinaire canadienne.

[6]  J. Lillich,et al.  A limited surgical approach for pastern arthrodesis in horses with severe osteoarthritis , 2009, Veterinary and Comparative Orthopaedics and Traumatology.

[7]  D. Richardson.  Less invasive techniques for equine fracture repair and arthrodesis. , 2008, The Veterinary clinics of North America. Equine practice.

[8]  Tarun Goswami,et al.  A review of locking compression plate biomechanics and their advantages as internal fixators in fracture healing. , 2007, Clinical biomechanics.

[9]  D. Richardson,et al.  Minimally invasive plate fixation of lower limb injury in horses: 32 cases (1999-2003). , 2010, Equine veterinary journal.

[10]  G. Baxter,et al.  Comparison of intra-articular drilling and diode laser treatment for arthrodesis of the distal tarsal joints in normal horses. , 2010, Equine veterinary journal.

[11]  C. Kawcak,et al.  Comparison of three methods for arthrodesis of the distal intertarsal and tarsometatarsal joints in horses. , 2005, Veterinary surgery : VS.

[12]  Yasuhiko Tabata,et al.  Osteogenic differentiation of mesenchymal stem cells in biodegradable sponges composed of gelatin and beta-tricalcium phosphate. , 2005, Biomaterials.

[13]  Ulrich Dieter,et al.  Biomechanical testing of the LCP--how can stability in locked internal fixators be controlled? , 2003, Injury.

[14]  P. Aspenberg,et al.  Arthrodesis by percutaneous fixation: Patellofemoral arthrodesis in rabbits without debridement of the joint , 2002, Acta orthopaedica Scandinavica.

[15]  A. Allen,et al.  An evaluation of chemical arthrodesis of the proximal interphalangeal joint in the horse by using monoiodoacetate. , 2000, Canadian journal of veterinary research = Revue canadienne de recherche veterinaire.

[16]  U. Rydholm,et al.  Percutaneous ankle arthrodesis in the rheumatoid patient without débridement of the joint , 1998 .

[17]  P. Morley,et al.  An examination of the occurrence of surgical wound infection following equine orthopaedic surgery (1981-1990). , 1994, Equine veterinary journal.

[18]  J. Cummings,et al.  Substance P immunohistochemical study of the sensory innervation of normal subchondral bone in the equine metacarpophalangeal joint. , 1994, American journal of veterinary research.