A Fidelity-Embedded Regularization Method for Robust Electrical Impedance Tomography

Electrical impedance tomography (EIT) provides functional images of an electrical conductivity distribution inside the human body. Since the 1980s, many potential clinical applications have arisen using inexpensive portable EIT devices. EIT acquires multiple trans-impedance measurements across the body from an array of surface electrodes around a chosen imaging slice. The conductivity image reconstruction from the measured data is a fundamentally ill-posed inverse problem notoriously vulnerable to measurement noise and artifacts. Most available methods invert the ill-conditioned sensitivity or the Jacobian matrix using a regularized least-squares data-fitting technique. Their performances rely on the regularization parameter, which controls the trade-off between fidelity and robustness. For clinical applications of EIT, it would be desirable to develop a method achieving consistent performance over various uncertain data, regardless of the choice of the regularization parameter. Based on the analysis of the structure of the Jacobian matrix, we propose a fidelity-embedded regularization (FER) method and a motion artifact reduction filter. Incorporating the Jacobian matrix in the regularization process, the new FER method with the motion artifact reduction filter offers stable reconstructions of high-fidelity images from noisy data by taking a very large regularization parameter value. The proposed method showed practical merits in experimental studies of chest EIT imaging.

[1]  David Isaacson,et al.  Layer stripping: a direct numerical method for impedance imaging , 1991 .

[2]  G. Uhlmann,et al.  The Calderón problem with partial data , 2004, math/0405486.

[3]  Manuchehr Soleimani,et al.  Structural-functional lung imaging using a combined CT-EIT and a Discrete Cosine Transformation reconstruction method , 2016, Scientific Reports.

[4]  David Isaacson,et al.  NOSER: An algorithm for solving the inverse conductivity problem , 1990, Int. J. Imaging Syst. Technol..

[5]  Steffen Leonhardt,et al.  Chest electrical impedance tomography examination, data analysis, terminology, clinical use and recommendations: consensus statement of the TRanslational EIT developmeNt stuDy group , 2016, Thorax.

[6]  Kari Astala,et al.  Calderon's inverse conductivity problem in the plane , 2006 .

[7]  Willis J. Tompkins,et al.  Comparing Reconstruction Algorithms for Electrical Impedance Tomography , 1987, IEEE Transactions on Biomedical Engineering.

[8]  Robert V. Kohn,et al.  Determining conductivity by boundary measurements , 1984 .

[9]  J. Sylvester,et al.  A global uniqueness theorem for an inverse boundary value problem , 1987 .

[10]  B. Brown,et al.  Applied potential tomography: possible clinical applications. , 1985, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[11]  D. Isaacson Distinguishability of Conductivities by Electric Current Computed Tomography , 1986, IEEE Transactions on Medical Imaging.

[12]  Andreas Kirsch,et al.  Characterization of the shape of a scattering obstacle using the spectral data of the far field operator , 1998 .

[13]  Eung Je Woo,et al.  Imaging of regional air distributions in porcine lungs using high-performance electrical impedance tomography system , 2017, 2017 39th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC).

[14]  D C Barber,et al.  A sensitivity method for electrical impedance tomography. , 1989, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[15]  John G. Webster,et al.  An Impedance Camera for Spatially Specific Measurements of the Thorax , 1978, IEEE Transactions on Biomedical Engineering.

[16]  A. Adler,et al.  Impedance imaging of lung ventilation: do we need to account for chest expansion? , 1996, IEEE Transactions on Biomedical Engineering.

[17]  A. Nachman,et al.  Global uniqueness for a two-dimensional inverse boundary value problem , 1996 .

[18]  William R B Lionheart,et al.  Uses and abuses of EIDORS: an extensible software base for EIT , 2006, Physiological measurement.

[19]  William R B Lionheart EIT reconstruction algorithms: pitfalls, challenges and recent developments. , 2004, Physiological measurement.

[20]  Jie Zhang,et al.  EIT images of ventilation: what contributes to the resistivity changes? , 2005, Physiological measurement.

[21]  Martin Hanke,et al.  Recent progress in electrical impedance tomography , 2003 .

[22]  A. Calderón,et al.  On an inverse boundary value problem , 2006 .

[23]  B. Brown,et al.  Applied potential tomography. , 1989, Journal of the British Interplanetary Society.

[24]  David S. Holder,et al.  Electrical Impedance Tomography : Methods, History and Applications , 2004 .

[25]  E. Woo,et al.  Nonlinear Inverse Problems in Imaging , 2012 .

[26]  David Isaacson,et al.  A direct reconstruction algorithm for electrical impedance tomography , 2002, IEEE Transactions on Medical Imaging.

[27]  Jin Keun Seo,et al.  Regularizing a linearized EIT reconstruction method using a sensitivity-based factorization method , 2014, 1811.07616.

[28]  Samuli Siltanen,et al.  Linear and Nonlinear Inverse Problems with Practical Applications , 2012, Computational science and engineering.

[29]  D. Isaacson,et al.  An implementation of the reconstruction algorithm of A Nachman for the 2D inverse conductivity problem , 2000 .

[30]  J P Kaipio,et al.  Assessment of errors in static electrical impedance tomography with adjacent and trigonometric current patterns. , 1997, Physiological measurement.

[31]  Jari P. Kaipio,et al.  Tikhonov regularization and prior information in electrical impedance tomography , 1998, IEEE Transactions on Medical Imaging.

[32]  Roel Snieder,et al.  Linear and Nonlinear Inverse Problems , 2000 .

[33]  A. Adler,et al.  Reconstruction of conductivity changes and electrode movements based on EIT temporal sequences , 2008, Physiological measurement.

[34]  David S. Holder Electrical impedance tomography , 2005 .

[35]  C. J. Kotre,et al.  A sensitivity coefficient method for the reconstruction of electrical impedance tomograms. , 1989, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[36]  A. Nachman,et al.  Reconstructions from boundary measurements , 1988 .

[37]  M. Soleimani,et al.  Imaging of conductivity changes and electrode movement in EIT , 2006, Physiological measurement.

[38]  Andy Adler,et al.  Uniform background assumption produces misleading lung EIT images , 2013, Physiological measurement.

[39]  Andrea Borsic,et al.  Regularisation methods for imaging from electrical measurements. , 2002 .

[40]  David Isaacson,et al.  Electrical Impedance Tomography , 1999, SIAM Rev..

[41]  B H Brown,et al.  Errors in reconstruction of resistivity images using a linear reconstruction technique. , 1988, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[42]  Michael Vogelius,et al.  A backprojection algorithm for electrical impedance imaging , 1990 .

[43]  Christian Putensen,et al.  Electrical impedance tomography guided ventilation therapy , 2007, Current opinion in critical care.

[44]  Andy Adler,et al.  Total Variation Regularization in Electrical Impedance Tomography , 2007 .

[45]  D. C. Barber,et al.  Three-dimensional electrical impedance tomography , 1996, Nature.

[46]  Steffen Leonhardt,et al.  Assessment of regional lung recruitment and derecruitment during a PEEP trial based on electrical impedance tomography , 2008, Intensive Care Medicine.