The Chennai glaucoma study: Prevalence and risk factors for glaucoma in cataract operated eyes in urban Chennai

We report the prevalence and risk factors for glaucoma among aphakes and pseudophakes in 3850 subjects who participated in a population-based study in urban south India. The subjects underwent an ophthalmic examination including applanation tonometry, gonioscopy, optic disc evaluation and frequency doubling perimetry. Glaucoma was diagnosed using the International Society of Geographical and Epidemiological Ophthalmology (ISGEO) criteria. Thirty eight, 15 aphakes and 23 pseudophakes (0.99% of 3850 subjects) of the 406 persons who had undergone cataract surgery were diagnosed with glaucoma. Aphakes/pseudophakes were at higher risk of glaucoma as compared to the phakic population (Odds Ratio: 2.71, 95% CI: 1. 94, 3.38, p=0.001). On multivariate analysis, older age and higher intra ocular pressure were risk factors for glaucoma. Blindness attributable to glaucoma was detected in 20% of aphakic and 4.3% of pseudophakic eyes. Glaucoma was a significant cause of morbidity in those who had undergone cataract surgery in this urban population.

[1]  Ramesh S. Ve,et al.  Outcomes of cataract surgery in a rural and urban south Indian population , 2010, Indian journal of ophthalmology.

[2]  Praveen Vashist,et al.  Current status of cataract blindness and Vision 2020: The right to sight initiative in India , 2008, Indian journal of ophthalmology.

[3]  C. McCarty,et al.  Prevalence of primary open-angle glaucoma in an urban south Indian population and comparison with a rural population. The Chennai Glaucoma Study. , 2008, Ophthalmology.

[4]  C. McCarty,et al.  Glaucoma in aphakia and pseudophakia in the Chennai Glaucoma Study , 2005, British Journal of Ophthalmology.

[5]  N. Bharucha,et al.  BMC Public Health BioMed Central Research article Hypertension in the Parsi community of Bombay: a study on prevalence, awareness and compliance to treatment , 2002 .

[6]  C. McCarty,et al.  Methods and design of the Chennai Glaucoma Study , 2003, Ophthalmic epidemiology.

[7]  A. Rotchford,et al.  Glaucoma in Zulus: a population-based cross-sectional survey in a rural district in South Africa. , 2002, Archives of ophthalmology.

[8]  P. Foster,et al.  The definition and classification of glaucoma in prevalence surveys , 2002, The British journal of ophthalmology.

[9]  H R Taylor,et al.  Prevalence and predictors of open-angle glaucoma: results from the visual impairment project. , 2001, Ophthalmology.

[10]  E. Lamb,et al.  New diagnostic criteria for diabetes mellitus: are we any further forward? , 2000, Annals of clinical biochemistry.