Effects of chronic exposure to an anabolic androgenic steroid cocktail on α5-receptor-mediated GABAergic transmission and neural signaling in the forebrain of female mice

[1]  R. Pearce,et al.  GABAA receptor alpha5 subunits contribute to GABAA,slow synaptic inhibition in mouse hippocampus. , 2009, Journal of neurophysiology.

[2]  K. Ressler,et al.  Training‐induced changes in the expression of GABAA‐associated genes in the amygdala after the acquisition and extinction of Pavlovian fear , 2007, The European journal of neuroscience.

[3]  L. Henderson.  Steroid modulation of GABAA receptor-mediated transmission in the hypothalamus: Effects on reproductive function , 2007, Neuropharmacology.

[4]  B. L. Jones,et al.  Sex- and age-specific effects of anabolic androgenic steroids on reproductive behaviors and on GABAergic transmission in neuroendocrine control regions , 2006, Brain Research.

[5]  A. D. De Blas,et al.  Synaptic and nonsynaptic localization of GABAA receptors containing the α5 subunit in the rat brain , 2006 .

[6]  G. Dawson,et al.  L-655,708 enhances cognition in rats but is not proconvulsant at a dose selective for α5-containing GABAA receptors , 2006, Neuropharmacology.

[7]  G. Carboni,et al.  Neurosteroids regulate mouse aggression induced by anabolic androgenic steroids , 2006, Neuroreport.

[8]  B. L. Jones,et al.  Mechanisms of anabolic androgenic steroid inhibition of mammalian ɛ‐subunit‐containing GABAA receptors , 2006 .

[9]  I. Módy,et al.  Hippocampal network hyperactivity after selective reduction of tonic inhibition in GABA A receptor alpha5 subunit-deficient mice. , 2006, Journal of neurophysiology.

[10]  N Collinson,et al.  An Inverse Agonist Selective for α5 Subunit-Containing GABAA Receptors Enhances Cognition , 2006, Journal of Pharmacology and Experimental Therapeutics.

[11]  B. L. Jones,et al.  Sex-specific effects of chronic anabolic androgenic steroid treatment on GABAA receptor expression and function in adolescent mice , 2005, Neuroscience.

[12]  L. Coolen,et al.  Do similar neural systems subserve aggressive and sexual behaviour in male rats? Insights from c-Fos and pharmacological studies. , 2005, European journal of pharmacology.

[13]  D. Kullmann,et al.  Multiple and Plastic Receptors Mediate Tonic GABAA Receptor Currents in the Hippocampus , 2005, The Journal of Neuroscience.

[14]  B. L. Jones,et al.  Role of the α subunit in the modulation of GABAA receptors by anabolic androgenic steroids , 2005, Neuropharmacology.

[15]  B. Kampa,et al.  Synaptic integration in dendritic trees. , 2005, Journal of neurobiology.

[16]  J. Goodson.  The vertebrate social behavior network: Evolutionary themes and variations , 2005, Hormones and Behavior.

[17]  S. Gammie.  Current models and future directions for understanding the neural circuitries of maternal behaviors in rodents. , 2005, Behavioral and cognitive neuroscience reviews.

[18]  M. Farrant,et al.  Variations on an inhibitory theme: phasic and tonic activation of GABAA receptors , 2005, Nature Reviews Neuroscience.

[19]  V. V. Dolgov,et al.  GABAA receptors containing the α5 subunit mediate the trace effect in aversive and appetitive conditioning and extinction of conditioned fear , 2004, The European journal of neuroscience.

[20]  D. Kullmann,et al.  Tonically active GABAA receptors: modulating gain and maintaining the tone , 2004, Trends in Neurosciences.

[21]  B. Orser,et al.  Tonic inhibition in mouse hippocampal CA1 pyramidal neurons is mediated by α5 subunit-containing γ-aminobutyric acid type A receptors , 2004 .

[22]  L. Henderson,et al.  Behavioral and physiological responses to anabolic-androgenic steroids , 2003, Neuroscience & Biobehavioral Reviews.

[23]  Russell G Foster,et al.  Experimental validation of novel and conventional approaches to quantitative real-time PCR data analysis. , 2003, Nucleic acids research.

[24]  L. Demers,et al.  Measures of aggression and mood changes in male weightlifters with and without androgenic anabolic steroid use. , 2003, Journal of forensic sciences.

[25]  D. Leysen,et al.  Tibolone is not converted by human aromatase to 7α-methyl-17α-ethynylestradiol (7α-MEE): Analyses with sensitive bioassays for estrogens and androgens and with LC-MSMS , 2003, Steroids.

[26]  E. Burón,et al.  Anxiogenic-like activity of L-655,708, a selective ligand for the benzodiazepine site of GABAA receptors which contain the alpha-5 subunit, in the elevated plus-maze test , 2002, Progress in Neuro-Psychopharmacology and Biological Psychiatry.

[27]  T. Umbreit,et al.  Effects of 17α-methyltestosterone on uterine morphology and heat shock protein expression are mediated through estrogen and androgen receptors , 2002, The Journal of Steroid Biochemistry and Molecular Biology.

[28]  L. Henderson,et al.  Anabolic androgenic steroids induce age-, sex-, and dose-dependent changes in GABAA receptor subunit mRNAs in the mouse forebrain , 2002, Neuropharmacology.

[29]  B. L. Jones,et al.  Mechanisms of anabolic androgenic steroid modulation of α1β3γ2L GABAA receptors , 2002, Neuropharmacology.

[30]  T. V. Sewards,et al.  Fear and power-dominance drive motivation: neural representations and pathways mediating sensory and mnemonic inputs, and outputs to premotor structures , 2002, Neuroscience & Biobehavioral Reviews.

[31]  F. Kuenzi,et al.  Enhanced Learning and Memory and Altered GABAergic Synaptic Transmission in Mice Lacking the α5 Subunit of the GABAAReceptor , 2002, The Journal of Neuroscience.

[32]  K. Vogt,et al.  Trace fear conditioning involves hippocampal α5 GABAA receptors , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[33]  L. Henderson,et al.  The function and the expression of forebrain GABA(A) receptors change with hormonal state in the adult mouse. , 2002, Journal of neurobiology.

[34]  Thomas D. Schmittgen,et al.  Analysis of relative gene expression data using real-time quantitative PCR and the 2(-Delta Delta C(T)) Method. , 2001, Methods.

[35]  A. Dobs,et al.  Clinical review 138: Anabolic-androgenic steroid therapy in the treatment of chronic diseases. , 2001, The Journal of clinical endocrinology and metabolism.

[36]  N. Shahidi.  A review of the chemistry, biological action, and clinical applications of anabolic-androgenic steroids. , 2001, Clinical therapeutics.

[37]  George Paxinos,et al.  The Mouse Brain in Stereotaxic Coordinates , 2001 .

[38]  Hagai Bergman,et al.  The neuronal refractory period causes a short-term peak in the autocorrelation function , 2001, Journal of Neuroscience Methods.

[39]  C. Yesalis.  Anabolic Steroids in Sport and Exercise , 2000 .

[40]  Akira Kato,et al.  Neuronal activity in female rat preoptic area associated with sexually motivated behavior , 2000, Brain Research.

[41]  E. Kouri,et al.  Effects of supraphysiologic doses of testosterone on mood and aggression in normal men: a randomized controlled trial. , 2000, Archives of general psychiatry.

[42]  A. Gruber,et al.  Psychiatric and Medical Effects of Anabolic-Androgenic Steroid Use in Women , 1999, Psychotherapy and Psychosomatics.

[43]  I. Soltesz,et al.  GABA(A) receptor-mediated miniature postsynaptic currents and alpha-subunit expression in developing cortical neurons. , 1999, Journal of neurophysiology.

[44]  S. Newman.  The Medial Extended Amygdala in Male Reproductive Behavior A Node in the Mammalian Social Behavior Network , 1999, Annals of the New York Academy of Sciences.

[45]  S. Robinson,et al.  Inhibition of Estrogen-Induced Sexual Receptivity by Androgens: Role of the Androgen Receptor , 1998, Hormones and Behavior.

[46]  Deborah Dewar,et al.  Rat and Human Hippocampal α5 Subunit-Containing γ-Aminobutyric AcidA Receptors Have α5β3γ2 Pharmacological Characteristics , 1998 .

[47]  A. S. Clark,et al.  Stanozolol, Oxymetholone, and Testosterone Cypionate Effects on the Rat Estrous Cycle , 1998, Physiology & Behavior.

[48]  M. Selmanoff,et al.  Castration Decreases Single Cell Levels of mRNA Encoding Glutamic Acid Decarboxylase in the Diagonal Band of Broca and the Sexually Dimorphic Nucleus of the Preoptic Area , 1997, Journal of neuroendocrinology.

[49]  M. Häusser,et al.  Tonic Synaptic Inhibition Modulates Neuronal Output Pattern and Spatiotemporal Synaptic Integration , 1997, Neuron.

[50]  W. Franke,et al.  Hormonal doping and androgenization of athletes: a secret program of the German Democratic Republic government. , 1997, Clinical chemistry.

[51]  A. S. Clark,et al.  The Effects of 17α-Methyltestosterone, Methandrostenolone, and Nandrolone Decanoate on the Rat Estrous Cycle , 1997, Physiology & Behavior.

[52]  M. Leshem,et al.  Hemodialysis increases the preference for salt in soup , 1997, Physiology & Behavior.

[53]  P. Leeson,et al.  [3H]L-655,708, a Novel Ligand Selective for the Benzodiazepine Site of GABAA Receptors which Contain the α5 Subunit , 1996, Neuropharmacology.

[54]  R. Moore,et al.  The sexually dimorphic nucleus of the hypothalamus contains GABA neurons in rat and man , 1996, Brain Research.

[55]  Y. Sakuma,et al.  Diametrically opposite effects of estrogen on the excitability of female rat medial and lateral preoptic neurons with axons to the midbrain locomotor region , 1995, Neuroscience Research.

[56]  Y. Sakuma.  Estrogen-Induced Changes in the Neural Impulse Flow from the Female Rat Preoptic Region , 1994, Hormones and Behavior.

[57]  S. Ojeda,et al.  Androgens regulate aromatase cytochrome P450 messenger ribonucleic acid in rat brain. , 1994, Endocrinology.

[58]  O. Wolkowitz,et al.  Neuropsychiatric effects of anabolic steroids in male normal volunteers. , 1993, JAMA.

[59]  W. Yates,et al.  Illicit anabolic steroid use in athletes , 1990, The American journal of sports medicine.

[60]  M. McCarthy,et al.  Increased GABAergic transmission in medial hypothalamus facilitates lordosis but has the opposite effect in preoptic area , 1990, Brain Research.

[61]  D. Katz,et al.  Affective and psychotic symptoms associated with anabolic steroid use. , 1988, The American journal of psychiatry.

[62]  R. Mb,et al.  Adverse effects of anabolic steroids in athletes. , 1987 .

[63]  R. Dyer,et al.  Stimulation of single unit activity in the preoptic area and anterior hypothalamus, and secretion of luteinizing hormone, by ovarian steroids in ovariectomized rats with diencephalic islands , 1982, Proceedings of the Royal Society of London. Series B. Biological Sciences.

[64]  D. Pfaff,et al.  Single unit recording in hypothalamus and preoptic area of estrogen-treated and untreated ovariectomized female rats , 1976, Brain Research.

[65]  K. Ryan.  Biological aromatization of steroids. , 1959, The Journal of biological chemistry.

[66]  E. Hull,et al.  Male Sexual Behavior , 2010 .

[67]  Donald W. Pfaff,et al.  Hormones, brain, and behavior , 2009 .

[68]  L. Henderson,et al.  37 – Androgen Actions on Receptors and Channels: Regulation of Electrical Excitability and Synaptic Transmission , 2009 .

[69]  A. Thomson,et al.  Synaptic a 5 Subunit--Containing GABA A Receptors Mediate IPSPs Elicited by Dendrite-Preferring Cells in Rat Neocortex , 2008 .

[70]  T Sitalaximi,et al.  Autosomal microsatellite profile of three socially diverse ethnic Tamil populations of India. , 2003, Journal of forensic sciences.

[71]  J. Blaustein,et al.  Feminine Sexual Behavior , 2002 .

[72]  Michael Davis,et al.  The amygdala: vigilance and emotion , 2001, Molecular Psychiatry.

[73]  L. Henderson,et al.  Properties and sex-specific differences of GABAA receptors in neurons expressing gamma1 subunit mRNA in the preoptic area of the rat. , 1999, Journal of neurophysiology.

[74]  O. Rønnekleiv,et al.  Anatomic distribution and regulation of aromatase gene expression in the rat brain. , 1998, Biology of reproduction.

[75]  S. Winters,et al.  Androgens: endocrine physiology and pharmacology. , 1990, NIDA research monograph.

[76]  L. Martini,et al.  The 5alpha-reduction of testosterone in the neuroendocrine structures. Biochemical and physiological implications. , 1982, Endocrine reviews.

[77]  R. Gorski,et al.  Effects of estrogen on neuronal excitability in the hippocampal-septal-hypothalamic system. , 1975, Neuroendocrinology.

[78]  C. Gray,et al.  The metabolism of [1,2-3H]17-alpha-methyltestosterone in human subjects. , 1967, The Journal of endocrinology.