Rab5 and Rab7 Control Endocytic Sorting along the Axonal Retrograde Transport Pathway

[1]  Katrin Deinhardt,et al.  Tetanus toxin is internalized by a sequential clathrin-dependent mechanism initiated within lipid microdomains and independent of epsin1 , 2006, The Journal of cell biology.

[2]  E. Simpson,et al.  Als2-deficient mice exhibit disturbances in endosome trafficking associated with motor behavioral abnormalities. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[3]  Michael J Rust,et al.  Ligands for Clathrin-Mediated Endocytosis Are Differentially Sorted into Distinct Populations of Early Endosomes , 2006, Cell.

[4]  Robert H. Brown,et al.  Mice deficient in the Rab5 guanine nucleotide exchange factor ALS2/alsin exhibit age-dependent neurological deficits and altered endosome trafficking. , 2006, Human molecular genetics.

[5]  Giampietro Schiavo,et al.  Tetanus Toxin Is Transported in a Novel Neuronal Compartment Characterized by a Specialized pH Regulation* , 2005, Journal of Biological Chemistry.

[6]  B. Tucker,et al.  A procedure for selecting and culturing subpopulations of neurons from rat dorsal root ganglia using magnetic beads. , 2005, Brain research. Brain research protocols.

[7]  S. Saxena,et al.  The Small GTPase Rab7 Controls the Endosomal Trafficking and Neuritogenic Signaling of the Nerve Growth Factor Receptor TrkA , 2005, The Journal of Neuroscience.

[8]  M. Tremblay,et al.  Rab5 and Rab7, but Not ARF6, Govern the Early Events of HIV-1 Infection in Polarized Human Placental Cells1 , 2005, The Journal of Immunology.

[9]  Y. Kalaidzidis,et al.  Rab Conversion as a Mechanism of Progression from Early to Late Endosomes , 2005, Cell.

[10]  P. Brûlet,et al.  Internalization of a GFP-tetanus toxin C-terminal fragment fusion protein at mature mouse neuromuscular junctions , 2005, Molecular and Cellular Neuroscience.

[11]  A. Helenius,et al.  Rab7 Associates with Early Endosomes to Mediate Sorting and Transport of Semliki Forest Virus to Late Endosomes , 2005, PLoS biology.

[12]  P. Steiner,et al.  Differential endocytic sorting of p75NTR and TrkA in response to NGF: a role for late endosomes in TrkA trafficking , 2005, Molecular and Cellular Neuroscience.

[13]  S. Gamble,et al.  Androgen Receptor Is Targeted to Distinct Subcellular Compartments in Response to Different Therapeutic Antiandrogens , 2004, Clinical Cancer Research.

[14]  R. Orrell,et al.  A novel RAB7 mutation associated with ulcero‐mutilating neuropathy , 2004, Annals of neurology.

[15]  P. Saftig,et al.  Role for Rab7 in maturation of late autophagic vacuoles , 2004, Journal of Cell Science.

[16]  L. Goldstein,et al.  Microtubule-dependent transport in neurons: steps towards an understanding of regulation, function and dysfunction. , 2004, Current opinion in cell biology.

[17]  M. Colombo,et al.  Rab7 is required for the normal progression of the autophagic pathway in mammalian cells , 2004, Journal of Cell Science.

[18]  A. Burlingame,et al.  Differential Proteomics Reveals Multiple Components in Retrogradely Transported Axoplasm After Nerve Injury*S , 2004, Molecular & Cellular Proteomics.

[19]  E. Holzbaur.  Motor neurons rely on motor proteins. , 2004, Trends in cell biology.

[20]  Geoffrey Burnstock,et al.  Treatment with arimoclomol, a coinducer of heat shock proteins, delays disease progression in ALS mice , 2004, Nature Medicine.

[21]  G. Schiavo,et al.  Myosin Va and microtubule-based motors are required for fast axonal retrograde transport of tetanus toxin in motor neurons , 2003, Journal of Cell Science.

[22]  M. Snider.  A role for rab7 GTPase in growth factor-regulated cell nutrition and apoptosis. , 2003, Molecular cell.

[23]  S. Grinstein,et al.  Phagosomes Fuse with Late Endosomes and/or Lysosomes by Extension of Membrane Protrusions along Microtubules: Role of Rab7 and RILP , 2003, Molecular and Cellular Biology.

[24]  W. Mobley,et al.  NGF Signaling in Sensory Neurons Evidence that Early Endosomes Carry NGF Retrograde Signals , 2003, Neuron.

[25]  P. S. Amieux,et al.  Proteolytic Processing of the p75 Neurotrophin Receptor and Two Homologs Generates C-Terminal Fragments with Signaling Capability , 2003, The Journal of Neuroscience.

[26]  Yasushi Hiraoka,et al.  Mutations in Dynein Link Motor Neuron Degeneration to Defects in Retrograde Transport , 2003, Science.

[27]  T. Jovin,et al.  Ligand-Induced Internalization of the p75 Neurotrophin Receptor: A Slow Route to the Signaling Endosome , 2003, The Journal of Neuroscience.

[28]  G. Sobue,et al.  Heat Shock Protein 70 Chaperone Overexpression Ameliorates Phenotypes of the Spinal and Bulbar Muscular Atrophy Transgenic Mouse Model by Reducing Nuclear-Localized Mutant Androgen Receptor Protein , 2003, The Journal of Neuroscience.

[29]  Shin J. Oh,et al.  Mutant dynactin in motor neuron disease , 2003, Nature Genetics.

[30]  H. Hartung,et al.  Mutations in the small GTP-ase late endosomal protein RAB7 cause Charcot-Marie-Tooth type 2B neuropathy. , 2003, American journal of human genetics.

[31]  S. Pfeffer.  Membrane Domains in the Secretory and Endocytic Pathways , 2003, Cell.

[32]  W. Balch,et al.  Rab‐αGDI activity is regulated by a Hsp90 chaperone complex , 2002 .

[33]  G. Schiavo,et al.  Analysis of retrograde transport in motor neurons reveals common endocytic carriers for tetanus toxin and neurotrophin receptor p75NTR , 2002, The Journal of cell biology.

[34]  M. W. Wooten,et al.  Nerve growth factor stimulates the interaction of ZIP/p62 with atypical protein kinase C and targets endosomal localization: Evidence for regulation of nerve growth factor‐induced differentiation , 2001, Journal of cellular biochemistry.

[35]  F. Gisou van der Goot,et al.  The bacterial toxin toolkit , 2001, Nature Reviews Molecular Cell Biology.

[36]  Marino Zerial,et al.  Rab proteins as membrane organizers , 2001, Nature Reviews Molecular Cell Biology.

[37]  R. Parton,et al.  EEA1, a tethering protein of the early sorting endosome, shows a polarized distribution in hippocampal neurons, epithelial cells, and fibroblasts. , 2000, Molecular biology of the cell.

[38]  Bevil R. Conway,et al.  Cell Surface Trk Receptors Mediate NGF-Induced Survival While Internalized Receptors Regulate NGF-Induced Differentiation , 2000, The Journal of Neuroscience.

[39]  B. Deurs,et al.  Rab7: a key to lysosome biogenesis. , 2000, Molecular biology of the cell.

[40]  N. Morrice,et al.  A novel role for Rab5–GDI in ligand sequestration into clathrin-coated pits , 1998, Current Biology.

[41]  R. Campenot,et al.  Retrograde Transport and Steady-State Distribution of 125I-Nerve Growth Factor in Rat Sympathetic Neurons in Compartmented Cultures , 1997, The Journal of Neuroscience.

[42]  M. Zerial,et al.  Inhibition of rab5 GTPase activity stimulates membrane fusion in endocytosis. , 1994, The EMBO journal.

[43]  K. Rex,et al.  Influences of neurotrophins on mammalian motoneurons in vivo. , 1993, Journal of neurobiology.

[44]  Kai Simons,et al.  The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway , 1992, Cell.

[45]  E. McLachlan,et al.  Selective uptake of C-fragment of tetanus toxin by sympathetic preganglionic nerve terminals , 1990, Neuroscience.

[46]  M. Zerial,et al.  Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments , 1990, Cell.

[47]  H. Clark,et al.  Demonstration of the retrograde transport of nerve growth factor receptor in the peripheral and central nervous system , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[48]  P. Grob,et al.  Characterization of the human melanoma nerve growth factor receptor. , 1985, The Journal of biological chemistry.

[49]  R. Campenot,et al.  Binding, internalization, and retrograde transport of 125I-nerve growth factor in cultured rat sympathetic neurons , 1982, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[50]  K. Stöckel,et al.  Comparison between the retrograde axonal transport of nerve growth factor and tetanus toxin in motor, sensory and adrenergic neurons , 1975, Brain Research.

[51]  L. Goldstein,et al.  Microtubule-based transport systems in neurons: the roles of kinesins and dyneins. , 2000, Annual review of neuroscience.

[52]  F. Maxfield,et al.  Membrane transport in the endocytic pathway. , 1995, Current opinion in cell biology.