Laceration of the brain which is the outcome of gunshot wounds of the head, depressed fracture of the skull, and cranio-cerebral operations results in meningo-cerebral adhesion. The adjacent brain comes to be vascularized through a scar from extracerebral blood vessels. This is a most important element in the production of posttraumatic epilepsy. Following the last war Wagstaffe (1928) made a critical stildy of the end-results in a series of soldiers who had received severe head injuries. He found that 1.6 per cent. of these patients became epileptic when the dura had not been penetrated, whereas 18.7 per cent. of those whose dura had been perforated developed post-traumatic epilepsy. It seemed obvious from his figures that penetration of the dura rendered epileptiform seizures ten times more likely to occur. Steinthal and Nagel (1926) concluded that severe injul y to the brain resulted in frank epilepsy in 28.9 per cent. and lesser forms of epilepsy in 35.5 per cent., making a total of 64.4 per cent. In the scars that result from such injuries must lie the secret of the high incidence of post-traumatic epilepsy, which may appear at any time up to ten or fifteen years after the injury (Penfield, 1924, 1927). Head injury without penetration of the dura rarely results in epilepsy, although the brain damage may be, and often is, greater. In such cases adhesions, if they form at all, are much less severe, and blood vessels rarely grow down throuLgh the scar and into the brain. The need for a method to exclude the brain from sLuperficial scars is apparent a method of restoring the subdural space that separates with a thin layer of fluid the pachymeninx from the leptomeninx. The use of amniotic membrane prepared as described below (amnioplastin) seems to solve this problem.