CD44 activation enhances acute monoblastic leukemia cell survival via Mcl-1 upregulation.
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[1] M. Zöller. CD44: can a cancer-initiating cell profit from an abundantly expressed molecule? , 2011, Nature Reviews Cancer.
[2] M. Konopleva,et al. Leukemia stem cells and microenvironment: biology and therapeutic targeting. , 2011, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[3] C. Chomienne,et al. CD44-ligation induces, through ERK1/2 pathway, synthesis of cytokines TNF-α and IL-6 required for differentiation of THP-1 monoblastic leukemia cells , 2010, Leukemia.
[4] K. Akashi,et al. FLT3-ITD up-regulates MCL-1 to promote survival of stem cells in acute myeloid leukemia via FLT3-ITD-specific STAT5 activation. , 2009, Blood.
[5] S. Fulda,et al. Adhesion-mediated apoptosis resistance in cancer. , 2009, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[6] Putty-Reddy Sudhir,et al. CD44 Engagement Promotes Matrix-Derived Survival through the CD44-SRC-Integrin Axis in Lipid Rafts , 2008, Molecular and Cellular Biology.
[7] J. Delaunay,et al. Contribution of GM-CSF and IL-8 to the CD44-induced differentiation of acute monoblastic leukemia , 2008, Leukemia.
[8] C. Nakaseko,et al. CD44 and hyaluronan engagement promotes dexamethasone resistance in human myeloma cells , 2008, European journal of haematology.
[9] M. Warr,et al. Unique biology of Mcl-1: therapeutic opportunities in cancer. , 2008, Current molecular medicine.
[10] G. Mills,et al. Activation of integrin-linked kinase is a critical prosurvival pathway induced in leukemic cells by bone marrow-derived stromal cells. , 2007, Cancer research.
[11] C. Jasmin,et al. CD44 ligation induces caspase-independent cell death via a novel calpain/AIF pathway in human erythroleukemia cells , 2006, Oncogene.
[12] L. Bourguignon,et al. Hyaluronan and the interaction between CD44 and epidermal growth factor receptor in oncogenic signaling and chemotherapy resistance in head and neck cancer. , 2006, Archives of otolaryngology--head & neck surgery.
[13] C. Jasmin,et al. CD44 ligation induces apoptosis via caspase- and serine protease-dependent pathways in acute promyelocytic leukemia cells , 2005, Leukemia.
[14] Wolfgang Hiddemann,et al. FLT3-ITD-TKD dual mutants associated with AML confer resistance to FLT3 PTK inhibitors and cytotoxic agents by overexpression of Bcl-x(L). , 2005, Blood.
[15] S. Korsmeyer,et al. Obligate Role of Anti-Apoptotic MCL-1 in the Survival of Hematopoietic Stem Cells , 2005, Science.
[16] K. Tsan,et al. Activation of CD44 facilitates DNA repair in T-cell lymphoma but has differential effects on apoptosis induced by chemotherapeutic agents and ionizing radiation , 2005, Leukemia & lymphoma.
[17] J. Delaunay,et al. The Effect of Anti-CD44 Monoclonal Antibodies on Differentiation and Proliferation of Human Acute Myeloid Leukemia Cells , 2004, Leukemia & lymphoma.
[18] L. Gibson,et al. Regulation of Lymphoid and Myeloid Leukemic Cell Survival: Role of Stromal Cell Adhesion Molecules , 2004, Leukemia & lymphoma.
[19] N. Hanania,et al. Bcl-XL is required for heme synthesis during the chemical induction of erythroid differentiation of murine erythroleukemia cells independently of its antiapoptotic function. , 2003, Blood.
[20] A. Venditti,et al. Amount of spontaneous apoptosis detected by Bax/Bcl-2 ratio predicts outcome in acute myeloid leukemia (AML). , 2003, Blood.
[21] D. Johnson,et al. Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-XLand XIAP in the prolonged survival of monocytic cells , 2003, Leukemia.
[22] K. Koda,et al. CD44 signaling through focal adhesion kinase and its anti‐apoptotic effect , 2002, FEBS letters.
[23] E. Estey,et al. The anti‐apoptotic genes Bcl‐XL and Bcl‐2 are over‐expressed and contribute to chemoresistance of non‐proliferating leukaemic CD34+ cells , 2002, British journal of haematology.
[24] D. Fisher,et al. A CD44 survival pathway triggers chemoresistance via lyn kinase and phosphoinositide 3-kinase/Akt in colon carcinoma cells. , 2001, Cancer research.
[25] L. Altucci,et al. Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL , 2001, Nature Medicine.
[26] F. Appelbaum,et al. Acute myeloid leukemia cells are protected from spontaneous and drug-induced apoptosis by direct contact with a human bone marrow stromal cell line (HS-5). , 2001, Experimental hematology.
[27] A. O'Rourke,et al. Tissue- and epitope-specific mechanisms account for the diverse effects of anti-CD44 antibodies on the maintenance of primitive hematopoietic progenitors in vitro. , 2000, Blood cells, molecules & diseases.
[28] M. Allouche,et al. Ligation of the CD44 adhesion molecule inhibits drug-induced apoptosis in human myeloid leukemia cells. , 2000, Blood.
[29] Christine Chomienne,et al. Ligation of the CD44 adhesion molecule reverses blockage of differentiation in human acute myeloid leukemia , 1999, Nature Medicine.
[30] E. Solary,et al. Selective inhibition of apoptosis by TPA-induced differentiation of U937 leukemic cells , 1999, Cell Death and Differentiation.
[31] H. Kluin-Nelemans,et al. A strong expression of CD44-6v correlates with shorter survival of patients with acute myeloid leukemia. , 1998, Blood.
[32] John Calvin Reed,et al. Elevated expression of the apoptotic regulator Mcl-1 at the time of leukemic relapse. , 1998, Blood.
[33] I. Stamenkovic,et al. Induction of Apoptosis of Metastatic Mammary Carcinoma Cells In Vivo by Disruption of Tumor Cell Surface CD44 Function , 1997, The Journal of experimental medicine.
[34] M. Le Bousse-Kerdilès,et al. CD44 mediates hyaluronan binding by human myeloid KG1A and KG1 cells. , 1994, Blood.
[35] C. Tepper,et al. 1,25-Dihydroxyvitamin D3 protects HL60 cells against apoptosis but down-regulates the expression of the bcl-2 gene. , 1993, Experimental cell research.
[36] J. Magaud,et al. High expression of bcl-2 protein in acute myeloid leukemia cells is associated with poor response to chemotherapy. , 1993, Blood.
[37] Shigeru Tsuchiya,et al. Establishment and characterization of a human acute monocytic leukemia cell line (THP‐1) , 1980, International journal of cancer.
[38] R. Kalluri,et al. Contribution of bone microenvironment to leukemogenesis and leukemia progression , 2009, Leukemia.
[39] Roberta Riccioni,et al. Deregulation of apoptosis in acute myeloid leukemia. , 2007, Haematologica.
[40] P. Herrlich,et al. CD44: From adhesion molecules to signalling regulators , 2003, Nature Reviews Molecular Cell Biology.
[41] C. Jasmin,et al. Effects of anti-CD44 monoclonal antibodies on differentiation and apoptosis of human myeloid leukemia cell lines. , 2002, Blood.
[42] M. Konopleva,et al. Stromal cells prevent apoptosis of AML cells by up-regulation of anti-apoptotic proteins , 2002, Leukemia.