Development of optical transmitters for high-amplitude focused ultrasound

This paper investigates the use of thin-film optical transmitters to generate focused ultrasound, aiming to develop highamplitude focused ultrasound. Composite films were used as the optoacoustic sources, which consist of carbonnanotubes (CNTs) and elastomeric polymers. As the nano-composites work as excellent optical absorbers and efficient heat converters, thermo-elastic volume deformation within the composites produces strong optoacoustic pressure. These films were formed on concave substrates for optoacoustic generation of the focused ultrasound. A focal waveform was measured using a single-mode fiber-optic hydrophone. A peak positive pressure of ~4 MPa was achieved.

[1]  Lawrence A Crum,et al.  Acoustic characterization of high intensity focused ultrasound fields: a combined measurement and modeling approach. , 2008, The Journal of the Acoustical Society of America.

[2]  Ronald A. Roy,et al.  Applications of Acoustics and Cavitation to Noninvasive Therapy and Drug Delivery , 2008 .

[3]  J. E. Parsons,et al.  Cost-effective assembly of a basic fiber-optic hydrophone for measurement of high-amplitude therapeutic ultrasound fields. , 2006, The Journal of the Acoustical Society of America.

[4]  Hyoung Won Baac,et al.  Design of high-intensity focused ultrasound transmitters based on optoacoustic generation , 2011, 2011 IEEE International Ultrasonics Symposium.

[5]  V. Zharov,et al.  Golden carbon nanotubes as multimodal photoacoustic and photothermal high-contrast molecular agents. , 2009, Nature nanotechnology.

[6]  Yufeng Zhou,et al.  High intensity focused ultrasound in clinical tumor ablation. , 2011, World journal of clinical oncology.

[7]  井上 良紀,et al.  流体力学用語集 非線形音響学(Nonlinear acoustics) , 1995 .

[8]  C. Lafon,et al.  Blood clot disruption in vitro using shockwaves delivered by an extracorporeal generator after pre-exposure to lytic agent. , 2009, Ultrasound in medicine & biology.

[9]  Matthew O'Donnell,et al.  Optical generation of high frequency ultrasound using two-dimensional gold nanostructure , 2006 .

[10]  Matthew O'Donnell,et al.  High-frequency ultrasound array element using thermoelastic expansion in an elastomeric film , 2001 .

[11]  R. Cobbold Foundations of Biomedical Ultrasound , 2006 .

[12]  M. O'Donnell,et al.  Optoacoustic generation of high frequency sound for 3-D ultrasonic imaging in medicine , 2008, The European physical journal. Special topics.

[13]  Robin O Cleveland,et al.  Shock wave technology and application: an update. , 2011, European urology.

[14]  S. Krishnaswamy,et al.  LASER GENERATION OF ULTRASOUND IN FILMS AND COATINGS , 1999 .

[15]  H G Trier,et al.  Rigid piston approximation for computing the transfer function and angular response of a fiber-optic hydrophone. , 2000, The Journal of the Acoustical Society of America.

[16]  Tao Ling,et al.  Carbon nanotube composite optoacoustic transmitters for strong and high frequency ultrasound generation. , 2010, Applied physics letters.